Inhibitors of Electron Transport Chain and Oxidative Phosphorylation

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18 Questions

In ATP synthesis, what happens when the γ subunit rotates by 120° in a counterclockwise direction?

Converts the T-form subunit into the O-form

What is the main role of the proton gradient in ATP synthesis?

Releasing ATP from the synthase

Which system introduces electrons from cytoplasmic NADH into the electron transport chain?

Malate–aspartate shuttle

How is electron motion across the membrane related to ATP synthesis?

Drives the rotation of the c ring

What is the ATP yield ratio for NADH in terms of ATP produced?

2.5 ATP per NADH

How does ADP enter the mitochondrial matrix?

Through an antiporter

What is the main function of Iron–sulfur proteins (FeSPs) in the electron transport chain?

Promote the flow of electrons

Which molecule is essential as a reactant for ATP synthesis?

Molecular O2

What is the role of ATPase in ATP synthesis?

Creates a proton-rich environment

Which molecular assembly carries out the oxidative phosphorylation of ADP or the synthesis of ATP?

ATP synthase

According to chemiosmotic coupling, what couples electron transport and ATP synthesis in the mitochondria?

Proton gradient (proton-motive force)

Which mechanism leads to the release of tightly bound ATP from ATP synthase?

Proton flow through ATP synthase

What is the main function of the Electron-transport chain (ETC) and Oxidative Phosphorylation?

Generating ATP

What is the role of the Proton Gradient in oxidative phosphorylation?

Creating a pH gradient within the mitochondrion

Which structure in the cell is responsible for hosting the Electron-transport chain and Oxidative Phosphorylation processes?

Mitochondria

What drives electron transfer in the Reduction Potentials of ETC?

Reduction potential of redox couples

Which process depends on the coupling between oxidation and phosphorylation?

Oxidative Phosphorylation

What is a common inhibitor that can block Electron-transport chain (ETC) and ATP synthase?

Cyanide

This quiz focuses on identifying inhibitors that can block the electron transport chain and oxidative phosphorylation processes in mitochondria. Topics covered include ETC, oxidative phosphorylation, and proton gradient.

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