Inhibitors of Electron Transport Chain and Oxidative Phosphorylation
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Questions and Answers

In ATP synthesis, what happens when the γ subunit rotates by 120° in a counterclockwise direction?

  • Forms a proton gradient
  • Halts ATP release
  • Converts the T-form subunit into the O-form (correct)
  • Allows ATP to be synthesized

    • What is the main role of the proton gradient in ATP synthesis?

  • Interconverting ADP and Pi
  • Forming ATP directly
  • Releasing ATP from the synthase (correct)
  • Allowing ATP to be synthesized

    • Which system introduces electrons from cytoplasmic NADH into the electron transport chain?

  • Krebs cycle
  • Glycolysis pathway
  • Malate–aspartate shuttle (correct)
  • Oxidative phosphorylation

    • How is electron motion across the membrane related to ATP synthesis?

    <p>Drives the rotation of the c ring</p> Signup and view all the answers

    What is the ATP yield ratio for NADH in terms of ATP produced?

    <p>2.5 ATP per NADH</p> Signup and view all the answers

    How does ADP enter the mitochondrial matrix?

    <p>Through an antiporter</p> Signup and view all the answers

    What is the main function of Iron–sulfur proteins (FeSPs) in the electron transport chain?

    <p>Promote the flow of electrons</p> Signup and view all the answers

    Which molecule is essential as a reactant for ATP synthesis?

    <p>Molecular O2</p> Signup and view all the answers

    What is the role of ATPase in ATP synthesis?

    <p>Creates a proton-rich environment</p> Signup and view all the answers

    Which molecular assembly carries out the oxidative phosphorylation of ADP or the synthesis of ATP?

    <p>ATP synthase</p> Signup and view all the answers

    According to chemiosmotic coupling, what couples electron transport and ATP synthesis in the mitochondria?

    <p>Proton gradient (proton-motive force)</p> Signup and view all the answers

    Which mechanism leads to the release of tightly bound ATP from ATP synthase?

    <p>Proton flow through ATP synthase</p> Signup and view all the answers

    What is the main function of the Electron-transport chain (ETC) and Oxidative Phosphorylation?

    <p>Generating ATP</p> Signup and view all the answers

    What is the role of the Proton Gradient in oxidative phosphorylation?

    <p>Creating a pH gradient within the mitochondrion</p> Signup and view all the answers

    Which structure in the cell is responsible for hosting the Electron-transport chain and Oxidative Phosphorylation processes?

    <p>Mitochondria</p> Signup and view all the answers

    What drives electron transfer in the Reduction Potentials of ETC?

    <p>Reduction potential of redox couples</p> Signup and view all the answers

    Which process depends on the coupling between oxidation and phosphorylation?

    <p>Oxidative Phosphorylation</p> Signup and view all the answers

    What is a common inhibitor that can block Electron-transport chain (ETC) and ATP synthase?

    <p>Cyanide</p> Signup and view all the answers

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