Inhibitors of Electron Transport Chain and Oxidative Phosphorylation
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Questions and Answers

In ATP synthesis, what happens when the γ subunit rotates by 120° in a counterclockwise direction?

  • Forms a proton gradient
  • Halts ATP release
  • Converts the T-form subunit into the O-form (correct)
  • Allows ATP to be synthesized

What is the main role of the proton gradient in ATP synthesis?

  • Interconverting ADP and Pi
  • Forming ATP directly
  • Releasing ATP from the synthase (correct)
  • Allowing ATP to be synthesized

Which system introduces electrons from cytoplasmic NADH into the electron transport chain?

  • Krebs cycle
  • Glycolysis pathway
  • Malate–aspartate shuttle (correct)
  • Oxidative phosphorylation

How is electron motion across the membrane related to ATP synthesis?

<p>Drives the rotation of the c ring (A)</p> Signup and view all the answers

What is the ATP yield ratio for NADH in terms of ATP produced?

<p>2.5 ATP per NADH (B)</p> Signup and view all the answers

How does ADP enter the mitochondrial matrix?

<p>Through an antiporter (D)</p> Signup and view all the answers

What is the main function of Iron–sulfur proteins (FeSPs) in the electron transport chain?

<p>Promote the flow of electrons (D)</p> Signup and view all the answers

Which molecule is essential as a reactant for ATP synthesis?

<p>Molecular O2 (D)</p> Signup and view all the answers

What is the role of ATPase in ATP synthesis?

<p>Creates a proton-rich environment (C)</p> Signup and view all the answers

Which molecular assembly carries out the oxidative phosphorylation of ADP or the synthesis of ATP?

<p>ATP synthase (C)</p> Signup and view all the answers

According to chemiosmotic coupling, what couples electron transport and ATP synthesis in the mitochondria?

<p>Proton gradient (proton-motive force) (B)</p> Signup and view all the answers

Which mechanism leads to the release of tightly bound ATP from ATP synthase?

<p>Proton flow through ATP synthase (C)</p> Signup and view all the answers

What is the main function of the Electron-transport chain (ETC) and Oxidative Phosphorylation?

<p>Generating ATP (C)</p> Signup and view all the answers

What is the role of the Proton Gradient in oxidative phosphorylation?

<p>Creating a pH gradient within the mitochondrion (B)</p> Signup and view all the answers

Which structure in the cell is responsible for hosting the Electron-transport chain and Oxidative Phosphorylation processes?

<p>Mitochondria (D)</p> Signup and view all the answers

What drives electron transfer in the Reduction Potentials of ETC?

<p>Reduction potential of redox couples (A)</p> Signup and view all the answers

Which process depends on the coupling between oxidation and phosphorylation?

<p>Oxidative Phosphorylation (A)</p> Signup and view all the answers

What is a common inhibitor that can block Electron-transport chain (ETC) and ATP synthase?

<p>Cyanide (C)</p> Signup and view all the answers

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