18 Questions
What is the main function of Cytochrome oxidase in the Electron Transport Chain?
Transfer electrons to oxygen
Which enzyme is responsible for catalyzing the oxidation-reduction reactions in the respiratory chain?
Oxidoreductases
What is the consequence of the oxidation of a compound in a redox reaction?
Removal of electrons
What role do Dehydrogenases play in the Electron Transport Chain?
Transfer electrons without oxygen involvement
Which enzyme catalyzes the removal of hydrogen, using oxygen as a hydrogen acceptor?
Oxidases
In the context of ETC inhibitors, what is a common function of most inhibitors?
Disrupt proton gradient formation
Which of the following correctly describes the role of the proton gradient in ATP synthesis?
Protons pump across the inner mitochondrial membrane, creating an electrical and pH gradient, which drives the rotation of the F1 domain of ATP synthase, leading to ATP production.
Which of the following is an inhibitor of Complex IV (cytochrome c oxidase) in the electron transport chain?
Carbon monoxide (CO)
Which of the following is a correct statement about uncouplers in the electron transport chain?
Uncouplers dissipate the electrochemical gradient across the inner mitochondrial membrane without generating ATP.
What is the primary role of oligomycin in the context of the electron transport chain and ATP synthesis?
It binds to the F0 domain of ATP synthase, preventing the re-entry of protons into the matrix and inhibiting ATP synthesis.
Which of the following statements is correct regarding mitochondrial DNA (mtDNA)?
mtDNA has a higher mutation rate compared to nuclear DNA, which can lead to mitochondrial diseases.
Which of the following is a correct statement regarding the inhibitors of the electron transport chain?
Cyanide (CN) is an inhibitor of Complex III in the electron transport chain.
Which of the following accurately describes the role of the F0 domain of ATP synthase in oxidative phosphorylation?
It couples the energy from the proton gradient to the phosphorylation of ADP to ATP.
Which of the following statements accurately describes the role of uncouplers in the electron transport chain?
They facilitate the dissipation of the proton gradient across the inner mitochondrial membrane without ATP synthesis.
Which of the following is a correct statement regarding the proton gradient generated by the electron transport chain?
The proton gradient provides the energy for the synthesis of ATP from ADP and inorganic phosphate.
Which of the following is an example of a respiratory chain inhibitor?
Oligomycin
Which of the following complexes of the electron transport chain is directly involved in pumping protons across the inner mitochondrial membrane?
Both Complex I and Complex III
Which of the following statements accurately describes the role of cytochromes in the electron transport chain?
Cytochromes facilitate the transfer of electrons between the complexes of the electron transport chain.
Test your knowledge on the components and function of the mitochondrial electron transport chain. Explore how the proton gradient drives ATP production through phosphorylation of ADP. Learn about inhibitors of the respiratory chain and their impact on cellular respiration.
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