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Microbiology: Virology - Pathogenesis & Lab Diagnosis of Viral Infections

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21 Questions

What is the stage of the infectious disease cycle where the host is infectious but does not exhibit clinical signs?

Subclinical infectious period

Which of the following best describes the relationship between pathogenicity and virulence?

Pathogenicity is a qualitative measure of a virus's ability to cause disease, while virulence is a quantitative measure of the severity of the disease caused.

What is the term used to describe the range of tissues that a virus can infect?

Tissue tropism

Which of the following factors can influence a virus's tissue tropism?

All of the above

Why are highly virulent avian influenza strains able to infect a wider range of tissues in birds compared to mammals?

Avian influenza viruses can replicate more efficiently in the intestinal tract of birds.

What is the stage of the infectious disease cycle where the host exhibits clinical signs of the disease?

Clinical period

Which of the following patterns of infection is characterized by the virus remaining in the host's body in a dormant state, with periodic reactivation and shedding of the virus?

Latent infection

Which of the following patterns of infection is characterized by the virus remaining in the host's body without causing any clinical signs, but with the potential to reactivate and cause disease?

Persistent asymptomatic infection

What type of cell cultures are transformed and immortal?

Continuous cell lines

Which type of cell culture can grow for up to 100 generations?

Diploid cell strains

What are the three main types of cell cultures used for viral diagnosis?

Primary, diploid, and continuous

What is the purpose of using immunoassays or molecular assays in viral diagnosis?

To detect noncytopathic infected cells

What is the main limitation of using respiratory fluids for viral diagnosis?

Not suitable for feces and vesicle fluid

Which of the following is a key step in the laboratory diagnosis of viral infections?

All of the above

What is the purpose of interpreting positive laboratory test results in the context of the clinical history and signs?

To ensure the accuracy of the laboratory test

What is the main advantage of using continuous cell lines for viral diagnosis?

They are transformed and immortal

What is a potential consequence of mutations in the HA that allow it to be cleaved by furins?

Development of cancer

What is one of the pathogenesis mechanisms associated with host cell damage?

Immune suppression

Which method is used for the detection and identification of viral nucleic acids?

Detection of viral antigens

What are the advantages of using electron microscopy for diagnosing viral infections?

Rapid diagnosis

What is a disadvantage associated with electron microscopy in diagnosing viral infections?

Low sensitivity

Explore the pathogenesis stages and laboratory diagnosis of viral infections in virology with Dr. Darryn Knobel. Learn about the infectious period, incubation period, clinical signs, and more.

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