Microbiology Chapter 15 Quiz: Immunity and Immunization

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Questions and Answers

B and T cells can only recognize and bind antigen that has been processed and presented on MHC molecules.

False

Select the line of defense that displays immunologic memory.

Third line defenses (correct)

Nonspecific line defenses

Second line defenses

First line defenses

Cell surface markers play important roles in the specific immune response for the recognition of both self and nonself molecules.

True

Select the statements that accurately reflect the process of antigen binding of B and T cells.

The antigen receptor on a B cell is an antibody molecule. Signup and view all the answers

Choose the phrase that describes MHC class I molecules.

Expressed on all human nucleated cells Signup and view all the answers

The specific immune response:

Involves memory of antigens from previous exposure. Signup and view all the answers

T cells:

Are responsible for cell-mediated immunity. Signup and view all the answers

Antigens:

Are molecules that can be recognized by B- or T-cells. Signup and view all the answers

After repeated exposure to foreign material, nonspecific immunity:

Continues to react the same way. Signup and view all the answers

_______ with antigen fragments displayed on their surfaces are known as antigen-presenting cells (APCs).

Macrophages Signup and view all the answers

When activated by antigen-presenting cells, helper T-cells release what cytokine that activates B-cells and cytotoxic T-cells?

Interleukin-2 Signup and view all the answers

Cytotoxic T-cells know that a cell is infected because:

It has antigens from the disease-causing microbe on its surface. Signup and view all the answers

B-cells differentiate into what type of cells that make antibodies?

plasma cells Signup and view all the answers

Antigen-presenting cells release what cytokine to activate helper T-cells?

Interleukin-1 Signup and view all the answers

A child with a genetic disorder that does not allow immature B-cells to develop would therefore not be able to make what?

antibodies Signup and view all the answers

Cytotoxic T-cells kill target cells by:

Exposing them to chemicals which induces apoptosis. Signup and view all the answers

The antibody producing progeny cells of a B-cell clone are called what?

plasma cells Signup and view all the answers

Characteristics of good antigens include all of the following EXCEPT:

Large, repetitive molecules Signup and view all the answers

There are no antigens that can stimulate B-cells directly.

False Signup and view all the answers

Study Notes

Specific Immunity and Immunization

B and T cells can recognize and bind to antigens without MHC processing; therefore, the statement is false.
The third line of defense in immunity is characterized by immunologic memory, allowing for faster responses upon re-exposure.
Cell surface markers are vital for the specificity of the immune response, enabling recognition of self versus nonself molecules.
B cells have antibody molecules as their antigen receptors, while T cells require MHC to bind processed antigens.
MHC class I molecules are expressed on all human nucleated cells, playing a critical role in antigen presentation.
The specific immune response, unlike the first two lines of defense, involves memory of previously encountered antigens.
T cells are primarily responsible for cell-mediated immunity, distinguishing their role from B-cells which produce antibodies.
Antigens are defined as molecules recognized by B or T cells, not limited to microbes but applicable to various potential threats.
Nonspecific immunity remains consistent in its response level even after repeated exposure to similar foreign material.
Macrophages serve as antigen-presenting cells (APCs) by displaying antigen fragments on their surfaces for T cell recognition.
Activated helper T-cells release interleukin-2, crucial for the activation of B-cells and cytotoxic T-cells in the immune response.
Cytotoxic T-cells detect infections through disease-associated antigens displayed on infected cell surfaces.
B-cells differentiate into plasma cells, which are responsible for antibody production in response to antigens.
APCs also release interleukin-1 to activate helper T-cells, linking innate recognition with adaptive immune response.
A genetic disorder preventing the development of immature B-cells results in an inability to produce antibodies, critical for adaptive immunity.
Cytotoxic T-cells induce apoptosis in target cells through the release of cytotoxic chemicals, ensuring elimination of infected cells.
The progeny of B-cell clones responsible for antibody production are known as plasma cells.
Good antigens are typically large and diverse but large, repetitive molecules do not stimulate a strong immune response compared to others like whole cells or viruses.
Contrary to the belief, some antigens can stimulate B-cells directly; thus, the statement claiming otherwise is false.

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Description

Test your knowledge with this quiz on specific immunity and immunization from Microbiology Chapter 15. Explore concepts such as B and T cells, lines of defense, and immunologic memory. Perfect for students looking to reinforce their understanding of immunological principles.