Microbiology and Infectious Diseases Quiz

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Questions and Answers

What is the primary habitat of Borellia recurrentis?

  • Human blood
  • Wild rodents and small mammals (correct)
  • Tropical forests
  • Urban environments

What condition is associated with infestations of head lice, body lice, or pubic lice?

  • Chronic itching
  • Pediculosis (correct)
  • Scabies
  • Dermatitis

How do body lice primarily attach their eggs?

  • Directly on the skin
  • In bedding materials
  • To the seams of clothing (correct)
  • To the base of human hair

What is NOT a potential condition spread by body lice?

<p>Cholera (D)</p> Signup and view all the answers

What symptoms are associated with tick-borne illness after being bitten?

<p>Sudden fever, chills, and nausea (C)</p> Signup and view all the answers

How do lice transmit Borellia organisms to humans?

<p>Through mucous membranes after being crushed (D)</p> Signup and view all the answers

What is the recommended action for a person exhibiting symptoms of tick-borne illness?

<p>Seek immediate medical treatment (A)</p> Signup and view all the answers

In what type of conditions do body lice infestations tend to spread rapidly?

<p>Crowded environments with poor hygiene (D)</p> Signup and view all the answers

Which of the following pollutants can be biodegraded by Acinetobacter strains?

<p>Chlorinated biphenyl (A), Benzene (B)</p> Signup and view all the answers

What type of bacteria is primarily represented in the family Enterobacteriaceae?

<p>Bacilli (D)</p> Signup and view all the answers

What is the primary metabolic characteristic of Enterobacter bacteria?

<p>Ferment sugars (B)</p> Signup and view all the answers

Which site is a common location for infections caused by pathogenic strains of Enterobacter?

<p>Urinary tract (B)</p> Signup and view all the answers

What condition can result from the release of endotoxins by dead bacterial cells?

<p>Endotoxic shock (B)</p> Signup and view all the answers

Which type of genetic material do Acinetobacter strains utilize in the degradation of phenol?

<p>Chromosomal DNA (C)</p> Signup and view all the answers

What is one function of Type I fimbriae found in Enterobacter bacteria?

<p>Adhesion to hosts (B)</p> Signup and view all the answers

Which of these is not a characteristic of Enterobacter bacteria?

<p>Strict aerobes (A)</p> Signup and view all the answers

Which organism is primarily responsible for human shigellosis?

<p>Shigella dysenteriae (D)</p> Signup and view all the answers

What are common symptoms associated with Shigella infection?

<p>Profuse diarrhea with blood (B)</p> Signup and view all the answers

What type of bacteria is Vibrio cholera?

<p>Comma-shaped bacterium (A)</p> Signup and view all the answers

How is cholera primarily transmitted?

<p>Fecal contamination of food and water (A)</p> Signup and view all the answers

What happens to a person with untreated cholera due to dehydration?

<p>They produce 10-20 liters of diarrhea a day (A)</p> Signup and view all the answers

Which marine organism is known to have a symbiotic relationship with Vibrionaceae bacteria?

<p>Puffer fish (C)</p> Signup and view all the answers

What type of toxin is synthesized by some species in the Family Vibrionaceae?

<p>Neurotoxin (D)</p> Signup and view all the answers

Which of the following food items is a potential source of salmonella contamination?

<p>Milk (B)</p> Signup and view all the answers

What is the primary role of E.coli in infants shortly after birth?

<p>It colonizes the gastrointestinal tract. (D)</p> Signup and view all the answers

Which E.coli strain is primarily responsible for causing diarrhea in children in the developing world?

<p>Enterotoxigenic E.coli (ETEC) (D)</p> Signup and view all the answers

What serious condition can be caused by the O157:H7 strain of E.coli?

<p>Hemolytic-uremic syndrome (C)</p> Signup and view all the answers

What characteristic is NOT associated with fecal coliform bacteria?

<p>Oxidase positive (A)</p> Signup and view all the answers

How do E.coli bacteria typically escape the intestinal tract?

<p>By perforations in the intestinal lining (D)</p> Signup and view all the answers

Which bacterium is commonly used as an indicator of fecal contamination?

<p>Escherichia coli (A)</p> Signup and view all the answers

Which of the following E.coli strains is known for causing profuse diarrhea similar to shigellosis?

<p>Enteroinvasive E.coli (EIEC) (D)</p> Signup and view all the answers

What type of toxins can E.coli bacteria produce?

<p>Both heat-stable and heat-labile enterotoxins (C)</p> Signup and view all the answers

What complication can result from neonatal gonococcal conjunctivitis if left untreated?

<p>Corneal scarring or perforation (C)</p> Signup and view all the answers

Which of the following conditions is a potential outcome of untreated N.gonorrhea infection in females?

<p>Infertility due to pelvic inflammatory disease (B)</p> Signup and view all the answers

What is a characteristic feature of Acinetobacter baumannii?

<p>Non-motile and oxidase-negative (B)</p> Signup and view all the answers

Acinetobacter species are primarily found in which types of environments?

<p>Water, sewage, and soil (C)</p> Signup and view all the answers

How do Acinetobacter species contribute to infections in hospitals?

<p>They can survive on medical equipment and human skin. (C)</p> Signup and view all the answers

What percentage of females infected with N.gonorrhea may experience infertility due to complications?

<p>10 to 20% (D)</p> Signup and view all the answers

What is a common characteristic of Acinetobacter species observed under magnification?

<p>Coccobacillary morphology occurring in pairs (C)</p> Signup and view all the answers

What is a potential consequence of a disseminated N.gonorrhea infection?

<p>Meningitis or endocarditis (B)</p> Signup and view all the answers

What temperature and duration is recommended to ensure food is safe from Salmonella infection?

<p>75 °C for at least 10 minutes (C)</p> Signup and view all the answers

Which symptom is NOT typically associated with Typhoid fever?

<p>Intense migraines (A)</p> Signup and view all the answers

What was the significant impact of Mary Mallon on public health regarding Typhoid fever?

<p>She was the first identified asymptomatic carrier. (A)</p> Signup and view all the answers

Which source of infection is NOT recognized for spreading Salmonella?

<p>Wild plants (A)</p> Signup and view all the answers

What is one of the key characteristics of untreated Typhoid fever?

<p>Progressive fever over weeks (D)</p> Signup and view all the answers

What is a common behavior that contributes to Salmonella outbreaks in institutional kitchens?

<p>Poor kitchen hygiene practices (C)</p> Signup and view all the answers

Which of the following is a vector for Salmonella transmission?

<p>Aquatic vertebrates (D)</p> Signup and view all the answers

At what temperature should food be heated to kill bacteria within one hour?

<p>55 °C (C)</p> Signup and view all the answers

Flashcards

Borrelia recurrentis

A spirochete bacterium that causes louse-borne relapsing fever in humans. It is transmitted by the human body louse (Pediculus humanus corporis).

Pediculosis

A condition where a person is infested with head lice, body lice, or pubic lice.

Pediculus humanus corporis

The human body louse, a parasite that transmits Borrelia recurrentis, causing relapsing fever in humans.

Body lice are vectors

The human body louse is a vector of epidemic typhus (Rickettsia prowazekii), trench fever (Bartonella quintana) and relapsing fever (Borrelia recurrentis).

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Relapsing fever cycle

The cycle of symptoms in relapsing fever, where the fever and other symptoms appear, disappear, and reappear again at intervals.

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Severe symptoms of relapsing fever

Relapsing fever is often accompanied by severe symptoms, including severe jaundice (yellowing of skin), mental changes, bleeding, and an abnormal ECG pattern.

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Transmission of relapsing fever

Relapsing fever is transmitted when an infected louse bites a person and the organism enters through mucous membranes or skin abrasions.

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Relapsing fever outbreaks occur in specific conditions

Relapsing fever is most common in crowded and unsanitary living conditions where hygiene is poor. Outbreaks occur during war, natural disasters, and in prisons.

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Gonorrheal Conjunctivitis

An inflammation of the conjunctiva (membrane lining the inner surface of the eyelid and covering the sclera) commonly occurring in newborns and preventable with silver nitrate or antibiotic treatment.

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Pelvic Inflammatory Disease (PID)

Inflammation and scarring within the fallopian tubes, potentially leading to infertility, caused by untreated gonorrhea spreading from the cervix into the pelvic area.

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Acinetobacter baumannii

A species of bacteria causing various infections, especially among hospitalized patients, often found in water, sewage, and soil.

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Acinetobacter's Environmental Adaptability

The ability of Acinetobacter to thrive on various surfaces, making them a common source of hospital-acquired infections.

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Urethritis

Inflammation of the urethra, the tube that carries urine from the bladder to the outside of the body.

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Prostatitis

Inflammation of the prostate gland, often caused by bacterial infection.

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Orchitis

Inflammation of the testicles, often caused by bacterial infection.

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Proctitis

A bacterial infection of the rectum, which can also occur in individuals engaged in anal sex.

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What is Acinetobacter known for?

Acinetobacter is a genus of bacteria known for its ability to break down various pollutants, including hydrocarbons, pesticides, and heavy metals. They contribute to bioremediation by detoxifying contaminated environments.

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How does Acinetobacter contribute to bioremediation?

Acinetobacter can utilize pollutants like biphenyl, chlorinated biphenyl, and phenol as energy sources, breaking them down to less harmful substances.

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What is Enterobacteriaceae?

Enterobacteriaceae is a family of bacteria commonly found in the intestines of humans and other animals, as well as in water and soil. They are often rod-shaped, gram-negative, and capable of fermenting sugars.

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Describe the characteristics of Enterobacteriaceae.

Members of Enterobacteriaceae are typically rod-shaped, gram-negative, and have the ability to ferment sugar, producing lactic acid and other byproducts.

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What does 'facultative anaerobe' mean in the context of Enterobacteriaceae?

Many Enterobacteriaceae are facultative anaerobes, meaning they can survive with or without oxygen.

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What is Enterobacter?

Enterobacter, a genus within Enterobacteriaceae, is known to cause opportunistic infections, particularly in immunocompromised individuals.

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What are endotoxins?

Endotoxins are released by dead bacterial cells and can cause systemic infection, leading to endotoxic shock, which can be fatal.

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What is Escherichia?

Escherichia, a common fecal coliform, is another example of a bacterium within the Enterobacteriaceae family.

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Heat kills Salmonella

Salmonella bacteria are killed by heat, perishing after an hour at 55°C (131°F) or half an hour at 60°C (140°F).

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Safe food temperature

To ensure Salmonella destruction, food should be heated for at least 10 minutes at 75°C (167°F) so that the center reaches this temperature.

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Typhoid fever symptoms

Typhoid fever, caused by Salmonella Typhi, is characterized by a gradual fever reaching 40°C (104°F), sweating, and stomach problems.

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Typhoid fever stages

Typhoid fever, untreated, progresses in four stages, each lasting about a week.

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Typhoid Mary

Mary Mallon, nicknamed "Typhoid Mary", was the first asymptomatic carrier of Salmonella Typhi in the US, infecting 53 people, with 3 deaths, while working as a cook.

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Salmonella sources

Sources include contaminated food, poor kitchen hygiene, excretions from infected individuals or animals, polluted water, and unhygienically thawed poultry.

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Salmonella's survival

Salmonella bacteria can survive for weeks in dry environments and months in water, often contaminating water sources.

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Salmonella carriers

Birds and reptiles, especially aquatic turtles, are key carriers of Salmonella bacteria.

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What is the role of E. coli in the human gut?

E. coli is a type of bacteria that normally lives in the human gut and helps with digestion. It is a facultative anaerobe, meaning it can live with or without oxygen.

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What are some ways E. coli can cause illness?

E. coli can cause food poisoning, especially if you eat unwashed vegetables or undercooked meat. A serious strain called O157:H7 can cause severe complications like kidney failure.

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How does pathogenic E. coli cause diarrhea?

E. coli can produce toxins that cause diarrhea. These toxins can be heat-stable (not destroyed by heat) or heat-labile (destroyed by heat).

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What are fecal coliforms?

Fecal coliforms are bacteria that are found in feces. Their presence in water can indicate contamination with human or animal waste.

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What is Enterotoxigenic E. coli (ETEC) known for?

ETEC strains cause diarrhea, especially in children in developing countries. They don't invade the gut lining, but produce toxins that cause watery diarrhea.

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What is Enteropathogenic E. coli (EPEC) known for?

EPEC strains can cause diarrhea by attaching to the lining of the intestines and altering the cells. This can lead to changes in the gut that cause diarrhea.

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What is Enteroinvasive E. coli (EIEC) known for?

EIEC strains cause diarrhea similar to shigellosis. This type of E. coli infects the colon and causes inflammation and bloody diarrhea.

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What is Enterohemorrhagic E. coli (EHEC) known for?

EHEC strains can cause severe diarrhea with blood and abdominal cramps. This type of E. coli is often associated with outbreaks from contaminated food, especially undercooked meat.

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Salmonella

A bacterium commonly found in poultry, cattle, and sheep, often contaminating food like milk, meat, and sometimes cracked eggs.

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Shigella dysenteriae

A type of bacteria that specifically causes dysentery in humans and apes.

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Vibrionaceae

A bacterial genus commonly found in fresh and saltwater environments, with some species causing illness in humans.

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Tetrodotoxin (TTX)

A powerful neurotoxin naturally found in certain marine creatures like Pufferfish. Produced by bacteria of the Vibrionaceae family.

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Vibrio cholerae

The causative agent of cholera, a serious diarrheal disease.

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Cholera

A disease characterized by severe watery diarrhea and dehydration, caused by the bacterium Vibrio cholerae.

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Cholera Transmission

The primary route of transmission for cholera is through contaminated food and water, often due to poor sanitation.

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Seafood Contamination

Seafood like oysters and mussels can become contaminated with Vibrio cholerae, posing a risk of infection.

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Study Notes

GRAM-NEGATIVE BACTERIA

  • General Characteristics:
    • Simple morphology, cellular arrangement
    • Do not form complex structures
    • Reproduce by transverse binary fission
    • Mostly heterotrophic, some saprophytes or parasites, some highly pathogenic or opportunistic
  • Spiriochetes:
    • Helical shape, flexible
    • Periplasmic flagella
    • Difficult to visualize with light microscopy (dark field microscopy needed)
    • Swim best in viscous media
    • Treponema pallidum:
      • Causes syphilis in humans
      • Transmitted sexually, transplacentally
      • Motile spirochete, corkscrew motion through viscous mediums (like mucus)
      • Stages of syphilis: primary (chancre), secondary (rash), latent (asymptomatic), tertiary (damage)
      • Diagnosis with blood tests; treatable with antibiotics (penicillin G, ceftriaxone)

Other Gram-Negative Bacteria

  • Borrelia recurrentis
    • Pathogen causing louse-borne or tick-borne relapsing fever
    • Parasite of wild rodents and small mammals
    • Microaerophilic
    • Transmission via lice bites
    • Symptoms include fever, chills, headaches, rash (2-9 days)
    • Treatable with antibiotics
  • Leptospira interrogans
    • Parasite, causes leptospirosis
    • Gram-negative spirochete
    • Periplasmic flagellum
    • Sources: alkaline water, soil, urine
    • Transmission: infected animal urine, contaminated water
    • Symptoms: flu-like, jaundice, liver and kidney damage
    • Transmission
    • Person to person or animal to person
    • Contaminated water
  • Campylobacter jejuni
    • Curved, helical-shaped
    • Gram-negative, non-sporeforming
    • Microaerophilic
    • Sources: contaminated water and food (especially poultry and undercooked meat)
    • Symptoms: severe debilitating food poisoning
  • Pseudomonas aeruginosa
    • Wide range of organic material for food consumption
    • Can be found in normal flora and in medical equipment
    • Causes infections (burns, cystic fibrosis, external ear infections, medical devices)
  • Legionella
    • Opportunistic pathogen
    • Inhaled from mist droplets (e.g. cooling towers, hot tubs)
    • Causes Legionnaires' disease, flu-like symptoms, pneumonia, and sometimes bronchitis.
  • Neisseria gonorrhoeae
    • Gram-negative diplococci
    • Causes gonorrhoea (sexually transmitted infection)
    • Symptoms: discharge, pain, inflammation
  • Acinetobacter
    • Saprophytic, found in water, soil, sewage
    • Opportunistic pathogen in hospitalized patients
  • Salmonella
    • Facultative anaerobes, rod-shaped bacteria
    • Causes food poisoning, including typhoid fever
  • Shigella
    • Gram-negative, facultatively anaerobic, rod shaped bacteria
    • Usually fecal-oral transmission
    • Causes dysentery
  • Vibrio cholerae
    • Gram-negative, curved rod shape bacterium
    • Causes cholera, a severe diarrheal infection
  • Haemophilus influenzae
    • Causes ear infections, eye infections (conjunctivitis)
  • The Rickettsias
    • Obligate intracellular parasites
    • Transferred via vectors (lice, fleas, ticks)
    • Cause diverse diseases such as typhus, spotted fever, and Rocky Mountain spotted fever.
  • Chlamydia
    • Gram-negative intracellular bacterium
    • Sexually transmitted (C. trachomatis)
    • Causes trachoma, an eye infection
    • Causes pelvic inflammatory disease
    • Q-fever: caused by Coxiella burnetii; it has similar form as Rickettsia;

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