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Questions and Answers
What is the primary amino acid involved in the biosynthesis of penicillin?
What is the primary amino acid involved in the biosynthesis of penicillin?
- Valine
- Cysteine
- Phenylalanine
- L-α-aminoadipate (correct)
What is the primary reason for adding phenyl-alanine or phenyl acetic acid during penicillin fermentation?
What is the primary reason for adding phenyl-alanine or phenyl acetic acid during penicillin fermentation?
- To enhance the growth of Penicillium chrysogenum
- To increase the yield of penicillin
- To produce only the desired penicillin G (correct)
- To reduce the production of pigments
Which of the following is NOT a characteristic of Penicillium notatum?
Which of the following is NOT a characteristic of Penicillium notatum?
- Low yield of penicillin
- High yield of penicillin
- Production of pigments
- Non-pigmented (correct)
What is the main advantage of using Penicillium chrysogenum mutants in penicillin production?
What is the main advantage of using Penicillium chrysogenum mutants in penicillin production?
Which of the following is an example of a secondary metabolite produced by microorganisms?
Which of the following is an example of a secondary metabolite produced by microorganisms?
What is the primary function of CaCO3 and KH2PO4 in penicillin fermentation?
What is the primary function of CaCO3 and KH2PO4 in penicillin fermentation?
What is the advantage of using fungal spores for steroid transformation?
What is the advantage of using fungal spores for steroid transformation?
What is the result of incubating Streptomyces spores with chloramphenicol?
What is the result of incubating Streptomyces spores with chloramphenicol?
What is the optimal incubation time for spore-catalyzed chloramphenicol transformation activity?
What is the optimal incubation time for spore-catalyzed chloramphenicol transformation activity?
What is the effect of adding glucose or acetate to the spores during incubation?
What is the effect of adding glucose or acetate to the spores during incubation?
What is the role of penicillin G acylase in biotransformation?
What is the role of penicillin G acylase in biotransformation?
What is the benefit of using microbial fermentation for antibiotic production?
What is the benefit of using microbial fermentation for antibiotic production?
What is the primary role of penicillin acylase in the industrial production of β-lactam antibiotics?
What is the primary role of penicillin acylase in the industrial production of β-lactam antibiotics?
What is the difference between fermentation and biotransformation?
What is the difference between fermentation and biotransformation?
Which of the following microorganisms is used in the industrial production of penicillin acylase?
Which of the following microorganisms is used in the industrial production of penicillin acylase?
What is the product of penicillin acylase hydrolysis of penicillin G?
What is the product of penicillin acylase hydrolysis of penicillin G?
What is the primary application of enzymatic biotransformation in the industrial production of β-lactam antibiotics?
What is the primary application of enzymatic biotransformation in the industrial production of β-lactam antibiotics?
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