13 Questions
Which term refers to the manner in which a disease develops?
Pathogenesis
What is the concept that describes the relationship between normal microbiota and host?
Normal infection
Which term refers to the ability of an infectious agent to cause disease?
Pathogenicity
What is the term for a microorganism that is able to cause disease in a plant, animal, or insect?
Pathogen
Which book provides information on Pharmaceutical Microbiology?
Denyer, Hodges, Gorman & Gilmore's Hugo and Russell's Pharmaceutical Microbiology
What is the measure of the extent to which an organism can inflict disease?
Virulence
Which term refers to the process whereby organisms enter host cell or tissue and spread in the body?
Invasion
What is the measure of the dose of an agent that kills 50% of the animals in a test group?
LD50
What is the number of pathogenic microbes entering a host called?
Dose
Which term refers to the ability to breach host defenses?
Infectivity
What is the term for a usually harmless microorganism that becomes pathogenic under favorable conditions?
Opportunistic pathogen
Which term refers to the ability to produce a toxin that contributes to the development of disease?
Toxigenicity
What is the number of microorganisms which kill 50% of host tissue cells (or 50% of animals in a test group) called?
"Lethal dose 50 (LD50)"
Study Notes
Disease Development and Microbiology
- Pathogenesis refers to the manner in which a disease develops.
Microbiota and Host Relationship
- Symbiosis describes the relationship between normal microbiota and host.
Infectious Agent Characteristics
- Virulence refers to the ability of an infectious agent to cause disease.
- Pathogen is a term for a microorganism that is able to cause disease in a plant, animal, or insect.
Pharmaceutical Microbiology Resource
- The book "Pharmaceutical Microbiology" provides information on pharmaceutical microbiology.
Disease Severity and Microbial Infection
- Virulence is the measure of the extent to which an organism can inflict disease.
- Inoculum is the number of pathogenic microbes entering a host.
- Invasiveness refers to the ability to breach host defenses.
Microbial Toxins and Infection
- Toxigenicity refers to the ability to produce a toxin that contributes to the development of disease.
- Opportunistic pathogen is a usually harmless microorganism that becomes pathogenic under favorable conditions.
Infection and Toxicity Measures
- LD50 (Lethal Dose 50) is the measure of the dose of an agent that kills 50% of the animals in a test group.
- ID50 (Infective Dose 50) is the number of microorganisms which kill 50% of host tissue cells (or 50% of animals in a test group).
Explore the principles of disease and the interaction between microorganisms and their host. Understand the relationship concept of normal microbiota, infection, and disease pathology. Learn to classify, describe, and establish the causes and ways of acquiring infectious diseases.
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