Microbe-Host Interaction and Principles of Disease

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Questions and Answers

Which term refers to the manner in which a disease develops?

  • Microbiota
  • Pathogenesis (correct)
  • Pathogen
  • Pathogenicity

What is the concept that describes the relationship between normal microbiota and host?

  • Normal infection (correct)
  • Pathogenicity
  • Pathogenesis
  • Koch’s postulates

Which term refers to the ability of an infectious agent to cause disease?

  • Pathogenicity (correct)
  • Pathogen
  • Pathogenesis
  • Microbiota

What is the term for a microorganism that is able to cause disease in a plant, animal, or insect?

<p>Pathogen (C)</p> Signup and view all the answers

Which book provides information on Pharmaceutical Microbiology?

<p>Denyer, Hodges, Gorman &amp; Gilmore's Hugo and Russell's Pharmaceutical Microbiology (C)</p> Signup and view all the answers

What is the measure of the extent to which an organism can inflict disease?

<p>Virulence (B)</p> Signup and view all the answers

Which term refers to the process whereby organisms enter host cell or tissue and spread in the body?

<p>Invasion (C)</p> Signup and view all the answers

What is the measure of the dose of an agent that kills 50% of the animals in a test group?

<p>LD50 (D)</p> Signup and view all the answers

What is the number of pathogenic microbes entering a host called?

<p>Dose (D)</p> Signup and view all the answers

Which term refers to the ability to breach host defenses?

<p>Infectivity (C)</p> Signup and view all the answers

What is the term for a usually harmless microorganism that becomes pathogenic under favorable conditions?

<p>Opportunistic pathogen (C)</p> Signup and view all the answers

Which term refers to the ability to produce a toxin that contributes to the development of disease?

<p>Toxigenicity (D)</p> Signup and view all the answers

What is the number of microorganisms which kill 50% of host tissue cells (or 50% of animals in a test group) called?

<p>&quot;Lethal dose 50 (LD50)&quot; (C)</p> Signup and view all the answers

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Study Notes

Disease Development and Microbiology

  • Pathogenesis refers to the manner in which a disease develops.

Microbiota and Host Relationship

  • Symbiosis describes the relationship between normal microbiota and host.

Infectious Agent Characteristics

  • Virulence refers to the ability of an infectious agent to cause disease.
  • Pathogen is a term for a microorganism that is able to cause disease in a plant, animal, or insect.

Pharmaceutical Microbiology Resource

  • The book "Pharmaceutical Microbiology" provides information on pharmaceutical microbiology.

Disease Severity and Microbial Infection

  • Virulence is the measure of the extent to which an organism can inflict disease.
  • Inoculum is the number of pathogenic microbes entering a host.
  • Invasiveness refers to the ability to breach host defenses.

Microbial Toxins and Infection

  • Toxigenicity refers to the ability to produce a toxin that contributes to the development of disease.
  • Opportunistic pathogen is a usually harmless microorganism that becomes pathogenic under favorable conditions.

Infection and Toxicity Measures

  • LD50 (Lethal Dose 50) is the measure of the dose of an agent that kills 50% of the animals in a test group.
  • ID50 (Infective Dose 50) is the number of microorganisms which kill 50% of host tissue cells (or 50% of animals in a test group).

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