6 Questions
Which domains of the alpha chain in class I MHC molecules form the walls and peptide-binding cleft?
Alpha1 and alpha2
Which domains of the alpha chain in class I MHC molecules contain the polymorphic residues?
Alpha1 and alpha2
What is the function of the invariant alpha3 domain in class I MHC molecules?
It binds to the CD8 T cell coreceptor
Which domains of class II MHC molecules contain the binding site for the CD4 T cell coreceptor?
α2 and β2 domains
What is the function of CD8 coreceptor in T cell activation?
It binds to class I MHC molecules
What is the size range of peptides that can be accommodated by the cleft formed by the α1 and β1 domains of class II MHC molecules?
Between 10 and 30 residues
Test your knowledge on Class I and Class II MHC molecules, their subunit compositions, and overall structures with this quiz. Keywords: MHC, peptide-binding cleft, α chain, β2-microglobulin, subunit composition, overall structure.
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