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Questions and Answers
Which domains of the alpha chain in class I MHC molecules form the walls and peptide-binding cleft?
Which domains of the alpha chain in class I MHC molecules form the walls and peptide-binding cleft?
- Alpha1 and alpha3
- Alpha2 and alpha4
- Alpha2 and alpha3
- Alpha1 and alpha2 (correct)
Which domains of the alpha chain in class I MHC molecules contain the polymorphic residues?
Which domains of the alpha chain in class I MHC molecules contain the polymorphic residues?
- Alpha1 and alpha3
- Alpha1 and alpha2 (correct)
- Alpha3 and alpha4
- Alpha2 and alpha3
What is the function of the invariant alpha3 domain in class I MHC molecules?
What is the function of the invariant alpha3 domain in class I MHC molecules?
- It contains the peptide-binding cleft
- It binds to the CD8 T cell coreceptor (correct)
- It binds to the CD4 T cell coreceptor
- It determines the subunit composition
Which domains of class II MHC molecules contain the binding site for the CD4 T cell coreceptor?
Which domains of class II MHC molecules contain the binding site for the CD4 T cell coreceptor?
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What is the function of CD8 coreceptor in T cell activation?
What is the function of CD8 coreceptor in T cell activation?
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What is the size range of peptides that can be accommodated by the cleft formed by the α1 and β1 domains of class II MHC molecules?
What is the size range of peptides that can be accommodated by the cleft formed by the α1 and β1 domains of class II MHC molecules?
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