MHC Genes and Proteins Quiz
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Questions and Answers

Which of the following cell types express class II molecules?

  • All nucleated cells
  • Dendritic cells, macrophages, and B lymphocytes
  • Only B lymphocytes
  • Thymic epithelial cells and endothelial cells (correct)

What is the significance of codominant expression of MHC genes?

  • It ensures that only one allele inherited from a parent is expressed
  • It enables individuals to succumb easily to newly encountered microbes
  • It maximizes the number of HLA proteins expressed by each individual (correct)
  • It allows for the expression of a large number of peptides

What is the difference in expression pattern between class I and class II molecules?

  • Class I molecules are expressed on all nucleated cells, while class II molecules are expressed mainly on dendritic cells, macrophages, and B lymphocytes (correct)
  • Class I molecules are expressed on thymic epithelial cells and endothelial cells, while class II molecules are expressed mainly on dendritic cells, macrophages, and B lymphocytes
  • Class I molecules are not expressed on any cell types, while class II molecules are expressed on all nucleated cells
  • Class I molecules are expressed mainly on dendritic cells, macrophages, and B lymphocytes, while class II molecules are expressed on all nucleated cells

Which of the following statements about MHC genes is true?

<p>MHC genes are the most polymorphic of all proteins in mammals (B)</p> Signup and view all the answers

How are MHC alleles inherited?

<p>Inherited from both parents (D)</p> Signup and view all the answers

What is the significance of MHC polymorphism?

<p>It ensures that a population can deal with the diversity of microbes (B)</p> Signup and view all the answers

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