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Histocompatibility Antigens in Transplantation

10 Questions

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Histocompatibility Antigens in Transplantation

Created by

@UnrestrictedWormhole

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Questions and Answers

What is the primary biological function of the HLA system?

To induce autoimmune diseases

To facilitate organ transplantation

To cause drug hypersensitivity reactions

To protect the body from pathogens and malignancy (correct)

Which of the following is NOT a potential detrimental effect of the HLA system at the individual level?

Protection from infectious diseases (correct)

Drug hypersensitivity reactions

Multiple autoimmune diseases

Transplant rejection

Which of the following HLA-associated diseases is NOT mentioned in the text?

Celiac disease

Parkinson's disease (correct)

Narcolepsy

Ankylosing spondylitis (AS)

What is the primary purpose of crossmatching against donor cells in the transplantation process?

<p>To detect sensitization to HLA antigens in the recipient</p> Signup and view all the answers

Which of the following is NOT a method of HLA typing mentioned in the text?

<p>Genetic sequencing</p> Signup and view all the answers

What is the primary purpose of identifying donor-specific antibodies in the recipient during the transplantation process?

<p>To determine the level of sensitization in the recipient</p> Signup and view all the answers

Which of the following statements about the HLA system is NOT true?

<p>It is not associated with any autoimmune diseases</p> Signup and view all the answers

What is the primary purpose of donor searches in the transplantation process?

<p>To identify suitable HSCT donors</p> Signup and view all the answers

Which of the following is NOT a potential application of an HLA laboratory in 2024?

<p>Development of new HLA typing technologies</p> Signup and view all the answers

Which of the following HLA-associated conditions is NOT mentioned in the text?

<p>Multiple sclerosis</p> Signup and view all the answers

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