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Questions and Answers
What classification does Methimazole fall under?
What classification does Methimazole fall under?
- Antihypertensive
- Antithyroid drug (correct)
- Antibiotic
- Analgesic
What is the action of Methimazole?
What is the action of Methimazole?
Inhibits synthesis of thyroid hormones
What is the typical dosage range for Methimazole?
What is the typical dosage range for Methimazole?
5-15 mg/day
What is the pregnancy category of Methimazole?
What is the pregnancy category of Methimazole?
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Does Methimazole cross the placenta or enter breast milk?
Does Methimazole cross the placenta or enter breast milk?
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What are some common side effects of Methimazole?
What are some common side effects of Methimazole?
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What are the nursing implications when administering Methimazole?
What are the nursing implications when administering Methimazole?
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Study Notes
Methimazole (Tapazole) Overview
- Classified as an antithyroid drug, used in the management of hyperthyroidism.
- Main action involves inhibiting the synthesis of thyroid hormones, helping to lower excessive hormone levels.
Dosage Information
- Typical dosage range is between 5 to 15 mg per day, tailored to individual patient needs and response.
Pregnancy Considerations
- Classified as Category D for pregnancy, indicating there is positive evidence of risk to the fetus.
Distribution Characteristics
- Methimazole crosses the placenta, meaning it can affect a developing fetus.
- It is also found in breast milk, posing potential exposure to nursing infants.
Side Effects
- Common side effects include paresthesias (tingling sensations), rash, nausea, vomiting, loss of taste, and more serious conditions like agranulocytosis (dangerously low white blood cell count), thrombocytopenia (low platelet count), and myalgia (muscle pain).
Nursing Implications
- Nursing staff should monitor patients for signs of bone marrow depression and bleeding tendencies.
- The use of barrier contraceptives is recommended for patients to prevent pregnancy during treatment.
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