Methimazole Overview and Indications

What is the generic name for Methimazole?

What is the trade name for Methimazole?

What is the classification of Methimazole?

Methimazole is administered to adults at an initial dose of ______ mg/day.

What is one of the actions of Methimazole?

Which of the following is NOT a use for Methimazole?

Methimazole is contraindicated in patients with a known allergy to antithyroid products.

What are some adverse effects of Methimazole?

What is one nursing implication for administering Methimazole?

Methimazole Overview

Generic Name: Methimazole
Trade Name: Tapazole

Classification

Drug Class: Antithyroid drug

Dosage Information

Adults: Start with 15-60 mg/day orally in three doses; maintenance is 5-15 mg/day
Pediatrics: Initial dose of 0.4 mg/kg/day orally; maintenance is approximately half the initial dose

Mechanism of Action

Primary Action: Inhibits the synthesis of thyroid hormones, helping to manage thyroid-related conditions

Indications

Clinical Uses: Effective for treating hyperthyroidism, Graves' Disease, and thyrotoxic crisis

Contraindications

Considerations: Not suitable for individuals with allergies to antithyroid products and during pregnancy; caution advised in cases of bone marrow depression

Adverse Effects

Potential Reactions: May cause paresthesias, neuritis, vertigo, drowsiness, depression, skin rashes, and gastrointestinal distress
Other Effects: Loss of taste, nephritis, myalgia, edema, lymphadenopathy, and drug fever

Nursing Implications

Administration Guidelines: Administer in three equal doses per day; breastfeeding is discouraged while on this medication
Patient Advice: Inform the patient about the increased risk of bleeding; confirm the patient's pregnancy status before initiation of therapy

This quiz covers the key aspects of Methimazole, including its classification as an antithyroid drug, dosage information for adults and pediatrics, and its clinical uses in treating thyroid conditions. Additionally, it highlights contraindications and potential adverse effects associated with the medication.