Methimazole Overview and Indications

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Questions and Answers

What is the generic name for Methimazole?

  • Tapazole
  • Antithyroid drug
  • Methimazole (correct)
  • Hyperthyroidism

What is the trade name for Methimazole?

  • Thyroid hormone
  • Tapazole (correct)
  • Antithyroid drug
  • Methimazole

What is the classification of Methimazole?

Antithyroid drug

Methimazole is administered to adults at an initial dose of ______ mg/day.

<p>15-60</p> Signup and view all the answers

What is one of the actions of Methimazole?

<p>Inhibits the synthesis of thyroid hormones (A)</p> Signup and view all the answers

Which of the following is NOT a use for Methimazole?

<p>Diabetes (B)</p> Signup and view all the answers

Methimazole is contraindicated in patients with a known allergy to antithyroid products.

<p>True (A)</p> Signup and view all the answers

What are some adverse effects of Methimazole?

<p>Paresthesias, vertigo, nausea (B)</p> Signup and view all the answers

What is one nursing implication for administering Methimazole?

<p>Give drug in three equal doses a day</p> Signup and view all the answers

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Study Notes

Methimazole Overview

  • Generic Name: Methimazole
  • Trade Name: Tapazole

Classification

  • Drug Class: Antithyroid drug

Dosage Information

  • Adults: Start with 15-60 mg/day orally in three doses; maintenance is 5-15 mg/day
  • Pediatrics: Initial dose of 0.4 mg/kg/day orally; maintenance is approximately half the initial dose

Mechanism of Action

  • Primary Action: Inhibits the synthesis of thyroid hormones, helping to manage thyroid-related conditions

Indications

  • Clinical Uses: Effective for treating hyperthyroidism, Graves' Disease, and thyrotoxic crisis

Contraindications

  • Considerations: Not suitable for individuals with allergies to antithyroid products and during pregnancy; caution advised in cases of bone marrow depression

Adverse Effects

  • Potential Reactions: May cause paresthesias, neuritis, vertigo, drowsiness, depression, skin rashes, and gastrointestinal distress
  • Other Effects: Loss of taste, nephritis, myalgia, edema, lymphadenopathy, and drug fever

Nursing Implications

  • Administration Guidelines: Administer in three equal doses per day; breastfeeding is discouraged while on this medication
  • Patient Advice: Inform the patient about the increased risk of bleeding; confirm the patient's pregnancy status before initiation of therapy

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