Methanol Poisoning and Antidote Quiz

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Questions and Answers

What is the antidote for methanol poisoning?

  • fomepizole (correct)
  • Acetaminophen
  • Ethanol
  • Ibuprofen

How does ethanol act as an antidote for methanol poisoning?

  • It neutralizes the acidity of methanol
  • It enhances the absorption of methanol in the body
  • It directly binds to methanol molecules
  • It competes for the same metabolic pathway as methanol (correct)

Why is it important to administer ethanol as an antidote for methanol poisoning?

  • To reduce the absorption of methanol in the body
  • To reverse the central nervous system effects of methanol
  • To increase the rate of methanol metabolism
  • To prevent the formation of toxic byproducts (correct)

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Study Notes

Methanol Poisoning Antidote

  • The antidote for methanol poisoning is ethanol.

Ethanol as an Antidote

  • Ethanol acts as a competitive inhibitor of the enzyme alcohol dehydrogenase, blocking the conversion of methanol to its toxic metabolites.
  • Ethanol has a higher affinity for alcohol dehydrogenase than methanol, thereby inhibiting the metabolism of methanol.

Administration of Ethanol

  • It is important to administer ethanol as an antidote for methanol poisoning to prevent the formation of toxic metabolites, which can cause blindness, seizure, and even death.
  • Timely administration of ethanol can help reduce the risk of these severe complications.

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