Metformin: Indications, Contraindications, and Side Effects
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Questions and Answers

What is the indication for Metformin?

  • Heart failure
  • Type 2 diabetes and gestational diabetes (correct)
  • Hypertension
  • Type 1 diabetes

What is a contra-indication for Metformin?

  • Severe infection
  • Liver problems (correct)
  • Circulation problems
  • Heart attack

What is the normal dose and frequency for Metformin?

  • 500 mg twice daily (correct)
  • 250 mg once daily
  • 1 g once daily
  • 2 g twice daily

What is a common or very common side effect of Metformin?

<p>Gastrointestinal disorder (A)</p> Signup and view all the answers

Which medication is recommended for preventing heart disease, heart attacks, and strokes?

<p>Atorvastatin (B)</p> Signup and view all the answers

What is a common side effect of Gliclazide?

<p>Hypoglycaemia (C)</p> Signup and view all the answers

Which medication should be avoided in severe kidney or liver disease and during pregnancy?

<p>Gliclazide (B)</p> Signup and view all the answers

What is a rare side effect of Atorvastatin?

<p>Memory loss (A)</p> Signup and view all the answers

Which medication should be used with caution in those with mild to moderate renal impairment due to the hazard of hypoglycaemia?

<p>Gliclazide (B)</p> Signup and view all the answers

What is a common side effect of Paracetamol when administered orally?

<p>Dyspepsia (D)</p> Signup and view all the answers

Which medication is classified as an analgesic and antipyretic?

<p>Paracetamol (B)</p> Signup and view all the answers

What should be avoided where possible in acute porphyrias, severe kidney or liver disease, and during pregnancy?

<p>Gliclazide (C)</p> Signup and view all the answers

Which medication should be used with caution in chronic kidney disease for primary and secondary prevention of cardiovascular events?

<p>Atorvastatin (A)</p> Signup and view all the answers

Which medication may cause constipation and sleep disorders as common side effects?

<p>Atorvastatin (C)</p> Signup and view all the answers

What is a rare side effect of Paracetamol with intravenous use?

<p>Malaise (A)</p> Signup and view all the answers

What serious condition is a contra-indication for the use of Metformin?

<p>Acute metabolic acidosis (A)</p> Signup and view all the answers

Which potential side effect of Metformin requires discontinuation of the medication?

<p>Hepatitis (B)</p> Signup and view all the answers

What should be avoided where possible in individuals taking Metformin?

<p>Tissue hypoxia (D)</p> Signup and view all the answers

What is the initial normal dose and frequency for Metformin?

<p>500 mg once daily (C)</p> Signup and view all the answers

Which medication should be avoided in individuals with acute porphyrias, severe kidney or liver disease, and during pregnancy?

<p>Gliclazide (C)</p> Signup and view all the answers

What is a rare side effect of Atorvastatin?

<p>Lupus-like syndrome (C)</p> Signup and view all the answers

What is a common or very common side effect of Metformin?

<p>Hypoglycaemia (D)</p> Signup and view all the answers

What is the indication for Metformin?

<p>Managing type 2 diabetes (A)</p> Signup and view all the answers

What is a common side effect of Gliclazide?

<p>Nausea (D)</p> Signup and view all the answers

What is a rare side effect of Paracetamol with intravenous use?

<p>Angioedema (B)</p> Signup and view all the answers

What should be avoided where possible in individuals with severe renal impairment?

<p>Gliclazide (C)</p> Signup and view all the answers

Which medication is classified as an analgesic and antipyretic?

<p>Paracetamol (D)</p> Signup and view all the answers

What is a contra-indication for Metformin?

<p>Hypersensitivity in liver or renal failure (B)</p> Signup and view all the answers

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