Questions and Answers
Which of these are examples of biguanides?
What are biguanides used to treat?
Type 2 diabetes
What is the main pharmacological action of biguanides?
Reduces production of glucose within the liver through suppression of glucogenesis.
Common side effects of biguanides include ______.
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Concurrent use of iodine-containing contrast for diagnostic tests may result in acute renal failure when using biguanides.
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Alcohol decreases the risk of lactic acidosis when taking biguanides.
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Study Notes
Biguanides Overview
- Biguanides are a class of oral medications used to treat type 2 diabetes, primarily represented by metformin (Glucophage).
- These drugs impact glucose production from digestion.
Pharmacological Action
- Biguanides reduce liver glucose production through the suppression of gluconeogenesis.
Side Effects
- Common side effects include:
- Metallic taste
- Diarrhea
- Anorexia
- Nausea
- Vomiting
- Vitamin B-12 and folic acid deficiencies
- Altered absorption of nutrients
Nursing Implications
- Use of iodine-containing contrast agents in diagnostic tests may lead to acute renal failure when combined with biguanides.
Important Interactions
- Alcohol consumption with biguanides elevates the risk of lactic acidosis, a condition of excess lactic acid in the body.
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Description
Explore the pharmacology of biguanides, a key class of oral diabetes medications, primarily represented by metformin. This quiz provides essential information about their usage, action, and examples. Perfect for students of pharmacology and medicine.
