Metaplasia in Pathology
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Questions and Answers

What is the primary characteristic of metaplasia?

  • Complete degeneration of tissue.
  • Uncontrolled cell division leading to cancer.
  • Reversible transformation of one differentiated cell type to another. (correct)
  • Permanent transformation of cell types.
  • Which of the following is a type of metaplasia that occurs in response to smoking?

  • Squamous metaplasia (correct)
  • Columnar metaplasia
  • Fibrous metaplasia
  • Glandular metaplasia
  • What is one of the primary causes of metaplasia?

  • Genetic mutations
  • Chronic irritation or inflammation (correct)
  • Acute infections
  • Increased tissue perfusion
  • Which of the following clinical significances are associated with metaplasia?

    <p>It can be a precursor to dysplasia and cancer.</p> Signup and view all the answers

    How can metaplasia typically be diagnosed?

    <p>Histological examination through biopsy.</p> Signup and view all the answers

    Study Notes

    Metaplasia Definition

    • A reversible change in which one adult cell type is replaced by another adult cell type

    Examples of Metaplasia

    • Squamous metaplasia in the respiratory tract of smokers
      • Normal ciliated columnar epithelium is replaced by stratified squamous epithelium
    • Barrett's esophagus
      • The normal squamous epithelium of the lower esophagus is replaced by columnar epithelium

    Causes of Metaplasia

    • Chronic irritation or injury
    • Cigarette smoke
    • Gastroesophageal reflux disease (GERD)
    • Vitamin A deficiency

    Clinical Significance of Metaplasia

    • It can be a precursor to cancer
    • Can be a sign of other underlying medical conditions
    • The new cell type may not function as well as the original cell type.

    Diagnosing Metaplasia

    • Biopsy
    • Microscopic examination

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    Description

    This quiz focuses on the key characteristics, causes, and clinical significance of metaplasia, an important concept in pathology. Test your knowledge on types of metaplasia related to smoking and its diagnosis. Perfect for students and professionals in the medical field.

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