Podcast
Questions and Answers
What is the primary characteristic of metaplasia?
What is the primary characteristic of metaplasia?
- Complete degeneration of tissue.
- Uncontrolled cell division leading to cancer.
- Reversible transformation of one differentiated cell type to another. (correct)
- Permanent transformation of cell types.
Which of the following is a type of metaplasia that occurs in response to smoking?
Which of the following is a type of metaplasia that occurs in response to smoking?
- Squamous metaplasia (correct)
- Columnar metaplasia
- Fibrous metaplasia
- Glandular metaplasia
What is one of the primary causes of metaplasia?
What is one of the primary causes of metaplasia?
- Genetic mutations
- Chronic irritation or inflammation (correct)
- Acute infections
- Increased tissue perfusion
Which of the following clinical significances are associated with metaplasia?
Which of the following clinical significances are associated with metaplasia?
How can metaplasia typically be diagnosed?
How can metaplasia typically be diagnosed?
Flashcards
Metaplasia Definition
Metaplasia Definition
Reversible transformation of one differentiated cell type to another.
Smoking-Related Metaplasia
Smoking-Related Metaplasia
Squamous metaplasia in the respiratory tract from chronic smoking.
Cause of Metaplasia
Cause of Metaplasia
Chronic irritation or inflammation.
Metaplasia Clinical Significance
Metaplasia Clinical Significance
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Metaplasia Diagnosis
Metaplasia Diagnosis
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Metaplasia Reversible?
Metaplasia Reversible?
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Dysplasia
Dysplasia
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Barrett's Esophagus
Barrett's Esophagus
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Study Notes
Metaplasia Definition
- A reversible change in which one adult cell type is replaced by another adult cell type
Examples of Metaplasia
- Squamous metaplasia in the respiratory tract of smokers
- Normal ciliated columnar epithelium is replaced by stratified squamous epithelium
- Barrett's esophagus
- The normal squamous epithelium of the lower esophagus is replaced by columnar epithelium
Causes of Metaplasia
- Chronic irritation or injury
- Cigarette smoke
- Gastroesophageal reflux disease (GERD)
- Vitamin A deficiency
Clinical Significance of Metaplasia
- It can be a precursor to cancer
- Can be a sign of other underlying medical conditions
- The new cell type may not function as well as the original cell type.
Diagnosing Metaplasia
- Biopsy
- Microscopic examination
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