Pathology: Fibrinoid Necrosis and Metaplasia
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Questions and Answers

What is Fibrinoid necrosis?

It is a type of necrosis characterized by a circumferential bright pink area caused by immune reactions where antigen-antibody complexes deposit in blood vessel walls.

Fibrinoid necrosis usually occurs in __________.

immune reactions

What kind of epithelium does the normal cervix have?

  • Simple Cuboidal Epithelium
  • Keratinized Squamous Epithelium
  • Columnar Epithelium
  • Non-keratinized Squamous Epithelium (correct)

What is Endocervical Squamous Metaplasia?

<p>It is a condition where normal columnar epithelium is replaced by squamous epithelium in response to irritation.</p> Signup and view all the answers

Squamous metaplasia can develop into dysplasia.

<p>True (A)</p> Signup and view all the answers

What is Acute cholecystitis?

<p>It is an acute inflammation of the gallbladder.</p> Signup and view all the answers

Study Notes

Fibrinoid Necrosis

  • Characterized by pink fibrinous material
  • Occurs in immune reactions where antigen-antibody complexes deposit in blood vessel walls
  • Can also occur in severe hypertension
  • Inflammation/vasculitis (neutrophils) are often present

Endocervical Squamous Metaplasia

  • Normal cervix has a smooth, glistening mucosal surface with a small rim of vaginal cuff
  • Cervical os is small and round in nulliparous women
  • The os has a fish-mouth shape after pregnancies
  • Normal cervix has a non-keratinized squamous epithelium on the outside and columnar epithelium on the inside
  • Squamous metaplasia occurs when there is irritation
  • The histological image shows normal endocervical epithelium and metaplastic squamous epithelium
  • If the entire metaplastic cell development results in dysplasia, it becomes Carcinoma in-situ
  • Cells are typical and not atypical because it is only metaplasia, not dysplasia

Acute Cholecystitis

  • Acute inflammation of the gallbladder
  • Gross features include:
    • Congestion
    • Redness
    • Wall thickness

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Description

Explore the key concepts of fibrinoid necrosis and endocervical squamous metaplasia, along with the implications of these conditions in pathology. This quiz covers physiological changes, inflammation responses, and histological features observed in these conditions.

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