Metabolism: Electron Transport Chain
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Metabolism: Electron Transport Chain

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Questions and Answers

What is the primary function of the electron transport chain in metabolism?

  • To break down fatty acids into acetyl-CoA
  • To convert pyruvate into lactate
  • To synthesize glucose from carbon dioxide
  • To produce ATP through oxidative phosphorylation (correct)
  • Which component indicated by 'Q-Cyt-' is involved in the electron transport chain?

  • Ubiquinone (coenzyme Q) (correct)
  • Coenzyme A
  • Cytochrome c
  • NADH
  • What is the concentration of protons ([H+]) mentioned in the context of the electron transport chain?

  • 50 mM
  • 10 mM (correct)
  • 5 mM
  • 1 mM
  • Which enzyme is labeled as 'Succinate D.H.' and plays a role in the electron transport chain?

    <p>Succinate dehydrogenase</p> Signup and view all the answers

    What is one of the main products of the electron transport chain operation?

    <p>ATP</p> Signup and view all the answers

    In the electron transport chain, what role does the proton gradient play?

    <p>It powers ATP synthase to generate ATP</p> Signup and view all the answers

    Which molecule is a key electron carrier in the process involving NAD+?

    <p>CoQ</p> Signup and view all the answers

    What role does FMN play in the electron transport chain?

    <p>It acts as an electron carrier.</p> Signup and view all the answers

    Which of the following molecules receives electrons directly from FMN?

    <p>CoQ</p> Signup and view all the answers

    Which component is primarily responsible for the transfer of electrons to O2 in the electron transport chain?

    <p>Cytochrome Oxidase</p> Signup and view all the answers

    What is the reduced form of CoQ known as in the electron transport chain?

    <p>CoQH2</p> Signup and view all the answers

    What does NAD+ primarily do in cellular respiration?

    <p>It accepts electrons and is reduced to NADH.</p> Signup and view all the answers

    What type of enzyme is represented by the term 'Oxidoreductase' in the provided content?

    <p>Enzyme that catalyzes oxidation-reduction reactions</p> Signup and view all the answers

    In the reaction depicted, which component is primarily responsible for electron transfer?

    <p>Cyt-c</p> Signup and view all the answers

    Which compound is directly reduced when NADH is oxidized in the process outlined?

    <p>CoQ</p> Signup and view all the answers

    What role does CoQ play in the biochemical process illustrated?

    <p>It shuttles electrons between enzyme complexes</p> Signup and view all the answers

    Which statement correctly describes the overall function of the enzymes and molecules presented?

    <p>They are involved in cellular respiration and energy production</p> Signup and view all the answers

    What is the resultant molecule when glucose is oxidized in the context provided?

    <p>Pyruvate</p> Signup and view all the answers

    What is the primary purpose of the electron transport chain in cellular metabolism?

    <p>To transport electrons to oxygen and produce ATP</p> Signup and view all the answers

    Which component enhances the efficiency of electron transport alongside cyt-c?

    <p>Cyt-b</p> Signup and view all the answers

    What is the role of NAD+ in the provided biochemical process?

    <p>It is a precursor to NADH.</p> Signup and view all the answers

    Which molecule is formed alongside 2 NADH during the biochemical reactions?

    <p>Malate</p> Signup and view all the answers

    What is the significance of FMN in the provided biochemical pathway?

    <p>It acts as a cofactor in various redox reactions.</p> Signup and view all the answers

    What are the end products of the conversion of pyruvate in this process?

    <p>Malate and NADH</p> Signup and view all the answers

    How many molecules of NADH are generated in this pathway?

    <p>Two molecules</p> Signup and view all the answers

    Which of the following compounds can be considered an oxidizing agent in this biochemical process?

    <p>NAD+</p> Signup and view all the answers

    Which compound is indicated as having two protons ($H^+$) associated with it?

    <p>OAA</p> Signup and view all the answers

    What role does FADH play in the process outlined?

    <p>It accepts electrons and is reduced to FAD.</p> Signup and view all the answers

    What do the terms DHAP and Glycerol refer to in this metabolic context?

    <p>They are intermediates in glycolysis.</p> Signup and view all the answers

    Which enzyme is suggested to interact with malate in this process?

    <p>Malate dehydrogenase</p> Signup and view all the answers

    Which molecule is produced when pyruvate is converted during metabolism?

    <p>Acetyl CoA</p> Signup and view all the answers

    What is the role of NAD+ in the metabolic process described?

    <p>It is reduced to form NADH.</p> Signup and view all the answers

    Which process involves the conversion of fatty acids into Acetyl CoA?

    <p>B-oxidation</p> Signup and view all the answers

    Which compound can be generated from the conversion of glutamate?

    <p>Aspartate</p> Signup and view all the answers

    What is the final product of the shuttle mechanism involving Glycerol-3-P?

    <p>FADH2</p> Signup and view all the answers

    Which of the following statements about NADH is correct?

    <p>NADH is produced during B-oxidation.</p> Signup and view all the answers

    Which oxidized form of organic compounds is represented by OAA?

    <p>Oxaloacetate</p> Signup and view all the answers

    During which metabolic phase are NADH and FADH2 primarily produced?

    <p>Krebs Cycle</p> Signup and view all the answers

    Which amino acid is directly linked to the production of Aspartate?

    <p>Glutamate</p> Signup and view all the answers

    In the metabolic pathway described, what is the fate of Acetyl CoA?

    <p>It enters the Krebs Cycle.</p> Signup and view all the answers

    Study Notes

    Overview of the Electron Transport Chain (ETC)

    • Core component of cellular respiration, occurring in the inner mitochondrial membrane.
    • Involves the transfer of electrons through a series of protein complexes to produce ATP.

    Key Elements

    • NADH and FADH₂ are the primary electron carriers; they donate electrons to the electron transport chain.
    • Coenzyme Q (CoQ) plays a crucial role in transferring electrons from the complexes to cytochromes.

    Electron Transport Process

    • NADH dehydrogenase (Complex I) accepts electrons from NADH, releasing protons (H⁺) into the mitochondrial matrix.
    • Succinate dehydrogenase (Complex II) oxidizes succinate to fumarate and transfers electrons from FADH₂ to CoQ.
    • Cytochrome b and cytochrome c are involved in the transfer of electrons further along the chain, contributing to the proton gradient.

    Proton Gradient and ATP Synthesis

    • The movement of electrons through ETC complexes causes protons to be pumped from the mitochondrial matrix into the intermembrane space, creating a proton gradient.
    • This gradient is utilized by ATP synthase to produce ATP through chemiosmosis.

    Important Metabolites and Intermediates

    • Pyruvate is converted into acetyl-CoA, entering the Krebs cycle to further contribute to NADH and FADH₂ production.
    • Malate and aspartate serve as important intermediates linking various metabolic pathways, maintaining the balance of NADH and NAD⁺ in mitochondria.

    Hydrogen Ion Concentration

    • An internal [H⁺] concentration of 10 mM is critical for maintaining the proton gradient necessary for ATP production.

    Metabolic Pathways Involvement

    • Fatty acid oxidation (β-oxidation) generates additional FADH₂ that enters the ETC.
    • Glycerol-3-phosphate shuttle transfers reducing equivalents from cytosolic NADH into mitochondria, enhancing productivity of the ETC.

    Factors Affecting ETC

    • Oxygen acts as the final electron acceptor at cytochrome oxidase, forming water.
    • Inhibition or malfunction of any ETC component can lead to reduced ATP production and increased production of reactive oxygen species (ROS).

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    Description

    Test your knowledge on the Electron Transport Chain, an essential part of metabolism. This quiz explores the key components and processes involved in energy production within cells. Perfect for students studying biochemistry or cellular biology.

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