18 Questions
What analogy is used to describe how bacteria develop resistance by producing a substance that fights against the antibiotic?
Lock and key
How is the concept of altering the structure of drug target molecules explained in the context of bacteria developing resistance?
Changing locks so the key no longer fits
What process leads to resistance development through advantageous random mutations?
Selection
In what way do bacteria develop resistance by causing drug inactivation?
Breaking down the antibiotic or making it inactive
How does excessive use of antibiotics lead to the dominance of resistant strains in a bacterial population?
By killing susceptible strains and allowing resistant strains to survive
Infections acquired in a healthcare setting, known as nosocomial infections, are often resistant due to what factor?
Usage of broad-spectrum antibiotics
What is the significance of high lactate levels in the blood during a severe infection?
Indicator of metabolic stress due to impaired oxygen delivery
In the context of antibiotic therapy, what do Broad Spectrum antibiotics target?
A wide variety of organisms
Which class of antibiotics disrupts bacterial protein synthesis and is reserved for serious systemic infections?
Aminoglycosides
Which mechanism of action do Bacteriostatic antibiotics primarily employ?
Inhibit bacterial synthesis of DNA and RNA
Which antibiotic is contraindicated in individuals under 18 years old and those with Myasthenia gravis?
Ciprofloxacin
What are the most common side effects associated with fluoroquinolones?
GI disturbances and superinfections
What is the role of creatinine in assessing kidney function?
Reflects the filtration efficiency of the kidneys
Which class of antibiotics inhibits DNA synthesis by bacterial enzymes?
Fluoroquinolones
What type of antibiotic would be most appropriate for an infection caused by a wide range of organisms?
Broad Spectrum antibiotic
How does septic shock contribute to the body's tissues not receiving adequate oxygen?
By promoting anaerobic metabolism in cells
What key nursing consideration is advised for individuals receiving aminoglycosides?
Instruct to take full prescribed treatment
What neurological disorder involves the body's immune system attacking its peripheral nervous system?
Guillain-Barré syndrome
Explore the relationship between metabolic stress, lactate levels, and the severity of infections or shock. Learn how high lactate levels in the blood can indicate tissue oxygen deprivation during severe infections.
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