10 Questions
What is the primary mechanism that can lead to the accumulation of fat in the liver?
Interference with the formation and release of lipoproteins from the cell due to a block in phospholipid synthesis caused by choline deficiency
Which of the following is NOT a potential cause of fatty liver mentioned in the text?
Increased transport of free fatty acids from adipose tissue
What is the characteristic gross appearance of a severely affected fatty liver?
Uniformly yellow with a greasy texture
What is the microscopic appearance of the fat accumulation in fatty liver?
Both large, discrete droplets and many tiny foamy droplets
What is the term used to describe the accumulation of adipose cells in a tissue where they are not normally present?
Fatty infiltration
What is the major organ involved in fat metabolism?
Liver
How are lipids transported to the liver from adipose tissue?
As free fatty acids
What is the term for the abnormal accumulation of triglycerides in parenchymal cells?
Steatosis
What are excess triglycerides within the liver often complexed with to be secreted?
Lipid acceptor proteins
What can result from defects in any one of the events from fatty acid entry to lipoprotein exit?
Excess accumulation of triglycerides
Explore the abnormal accumulation of major classes of lipids in cells, including triglycerides, cholesterol/cholesterol esters, and phospholipids. Learn about steatosis, fatty degeneration, and the common locations of lesions in parenchymal cells.
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