Metabolic Disorders of Lipids

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Questions and Answers

What is the primary mechanism that can lead to the accumulation of fat in the liver?

  • Decreased absorption of fatty acids from the intestine
  • Interference with the formation and release of lipoproteins from the cell due to a block in phospholipid synthesis caused by choline deficiency (correct)
  • Decreased release of free fatty acids from adipose tissue
  • Increased oxidation of fatty acids in the liver

Which of the following is NOT a potential cause of fatty liver mentioned in the text?

  • Dietary deficiency of certain amino acids
  • Increased transport of free fatty acids from adipose tissue (correct)
  • Blockage of oxidation of fatty acids in the liver
  • Inhibition of protein synthesis in the endoplasmic reticulum

What is the characteristic gross appearance of a severely affected fatty liver?

  • Uniformly brown with a normal texture
  • Enlarged with a firm, rubbery texture
  • Uniformly yellow with a greasy texture (correct)
  • Mottled with pale and normal brown areas

What is the microscopic appearance of the fat accumulation in fatty liver?

<p>Both large, discrete droplets and many tiny foamy droplets (C)</p> Signup and view all the answers

What is the term used to describe the accumulation of adipose cells in a tissue where they are not normally present?

<p>Fatty infiltration (A)</p> Signup and view all the answers

What is the major organ involved in fat metabolism?

<p>Liver (B)</p> Signup and view all the answers

How are lipids transported to the liver from adipose tissue?

<p>As free fatty acids (C)</p> Signup and view all the answers

What is the term for the abnormal accumulation of triglycerides in parenchymal cells?

<p>Steatosis (C)</p> Signup and view all the answers

What are excess triglycerides within the liver often complexed with to be secreted?

<p>Lipid acceptor proteins (D)</p> Signup and view all the answers

What can result from defects in any one of the events from fatty acid entry to lipoprotein exit?

<p>Excess accumulation of triglycerides (A)</p> Signup and view all the answers

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