Dyslipidemia: Abnormal Lipid Metabolism

Which of the following is characteristic of dyslipidemia?

Which lipoprotein is NOT mentioned as part of plasma lipoproteins?

What is the threshold for total cholesterol (TC) to be considered dyslipidemia according to the WHO?

What is the atherogenic index (AI) value above which dyslipidemia is defined according to the WHO?

Which of the following is NOT a characteristic of lipoproteins?

Which of the following HDL-C levels indicates dyslipidemia in women according to the WHO?

Dyslipidemia: Definition and Characteristics

A metabolic disease characterized by abnormal lipid metabolism
Hallmarked by elevated levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG), and decreased levels of high-density lipoprotein cholesterol (HDL-C)

Lipid Transport and Metabolism

Lipids are transported by lipoproteins, complex particles consisting of a central core of cholesterol esters and triglycerides, surrounded by free cholesterol, apolipoproteins, and phospholipids
Plasma lipoproteins include chylomicrons, chylomicron remnants, very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL-C), high-density lipoprotein (HDL-C), and lipoprotein-a (Lp-a)

World Health Organization (WHO) Definition

Dyslipidemia is defined as the presence of any of the following conditions:
- Total cholesterol (TC) > 200 mg/dl (> 5.2 mmol/l)
- Triglyceride (TG) > 150 mg/dl (> 1.7 mmol/l)
- Low-density lipoprotein cholesterol (LDL-C) > 135 mg/dl (> 3.5 mmol/l)
- High-density lipoprotein cholesterol (HDL-C) < 35 mg/dl (< 0.9 mmol/l in men) or < 40 mg/dl (< 1.0 mmol/l in women)
- Atherogenic index (AI) > 5

This quiz covers the basics of dyslipidemia, a metabolic disease characterized by abnormal lipid levels, and its role in cardiovascular disease. Learn about the importance of lipoproteins in lipid transport and the implications of dyslipidemia on health.