Podcast
Questions and Answers
Which of the following is a characteristic of an autosomal recessive disorder?
Which of the following is a characteristic of an autosomal recessive disorder?
Huntington's Disease is an example of a recessive disorder.
Huntington's Disease is an example of a recessive disorder.
False (B)
What is the primary function of CRISPR technology in genetic engineering?
What is the primary function of CRISPR technology in genetic engineering?
CRISPR technology allows for precise editing of DNA sequences, enabling targeted changes to genes.
A _ is an individual who carries one copy of a recessive allele but does not display the associated trait.
A _ is an individual who carries one copy of a recessive allele but does not display the associated trait.
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Match the following terms with their corresponding descriptions:
Match the following terms with their corresponding descriptions:
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What is the expected phenotype ratio of the F2 generation in a monohybrid cross between two heterozygous individuals?
What is the expected phenotype ratio of the F2 generation in a monohybrid cross between two heterozygous individuals?
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A homozygous individual possesses two identical alleles for a specific trait.
A homozygous individual possesses two identical alleles for a specific trait.
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What is the purpose of crossing over during meiosis?
What is the purpose of crossing over during meiosis?
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The process of cell division that produces two genetically identical daughter cells is called ______.
The process of cell division that produces two genetically identical daughter cells is called ______.
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Match the following genetic terms with their definitions:
Match the following genetic terms with their definitions:
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Which of the following best describes the role of meiosis in sexual reproduction?
Which of the following best describes the role of meiosis in sexual reproduction?
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Incomplete dominance occurs when the heterozygous phenotype is a blend of both parental phenotypes.
Incomplete dominance occurs when the heterozygous phenotype is a blend of both parental phenotypes.
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Explain the difference between mitosis and meiosis in terms of the number of daughter cells produced and their genetic composition.
Explain the difference between mitosis and meiosis in terms of the number of daughter cells produced and their genetic composition.
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Flashcards
Mendel's F2 Generation
Mendel's F2 Generation
75% tall plants and 25% short plants from a cross.
Dominant Allele
Dominant Allele
An allele that masks the effect of a recessive allele.
Homozygous
Homozygous
An organism with two identical alleles (e.g., AA or aa).
Heterozygous
Heterozygous
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Phenotype
Phenotype
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Meiosis
Meiosis
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Crossing Over
Crossing Over
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Sickle Cell Anemia
Sickle Cell Anemia
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Hemophilia
Hemophilia
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Huntington's Disease
Huntington's Disease
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Autosomal Recessive Trait
Autosomal Recessive Trait
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CRISPR
CRISPR
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Tumors
Tumors
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Study Notes
Mendel's Experiments
- Mendel studied trait inheritance in pea plants.
- F1 generation: All plants displayed the dominant trait (e.g., tall).
- F2 generation demonstrated a 3:1 ratio of dominant to recessive traits (e.g., 75% tall, 25% short).
- The tall allele (T) is dominant over the short allele (t).
Punnett Squares & Probability
- Punnett squares predict genotype and phenotype ratios.
- Dominant allele (A) masks the recessive allele (a).
- Recessive alleles are expressed when two copies are present (aa).
- Homozygous: Two identical alleles (AA or aa).
- Heterozygous: One dominant and one recessive allele (Aa).
- Genotype: Genetic makeup (e.g., Aa, AA, aa).
- Phenotype: Physical traits (e.g., eye color).
- Monohybrid cross: Involves one trait (like eye color).
- Dihybrid cross: Involves two traits (eye color & hair type); F2 ratio is 9:3:3:1.
- Codominance: Both alleles are fully expressed (e.g., speckled chicken).
- Incomplete dominance: Heterozygous phenotype is a blend (e.g., pink flowers from red and white).
- Example: BB (black) x ww (white) = all Bb (gray) rabbits demonstrates incomplete dominance.
Meiosis vs. Mitosis
Mitosis
- Purpose: Growth, repair, asexual reproduction.
- Results in two identical daughter cells.
- Maintains the chromosome number (diploid).
- One cell division.
Meiosis
- Purpose: Sexual reproduction, genetic variation.
- Results in four genetically unique gametes (haploid).
- Two cell divisions.
- Crossing over in Prophase I increases genetic variation.
- Independent assortment ensures unique combinations.
- Chromosome number reduces from 46 (diploid) to 23 (haploid).
Genetics Terminology
- Phenotype: Observable traits (e.g., eye color).
- Genotype: Genetic composition (e.g., BB, Bb, bb).
- Homozygous: Identical alleles (BB or bb).
- Heterozygous: Different alleles (Bb).
- Sex-linked traits: Carried on X and Y chromosomes.
- Mutation: Permanent DNA changes (harmful, neutral, or beneficial).
Genetic Disorders & Pedigrees
- Sickle cell anemia: Abnormally shaped red blood cells (recessive).
- Cystic fibrosis: Thick mucus in lungs and intestines (recessive).
- Hemophilia: Blood clotting disorder (sex-linked).
- Huntington's disease: Dominant disorder causing nerve degeneration.
- Pedigrees trace trait inheritance through generations.
- Carriers have one recessive allele but don't show the trait.
Human Genome & Genetic Engineering
- Human Genome Project: Mapped all human genes.
- Selective breeding: Choosing organisms with desired traits.
- Cloning: Creating genetically identical organisms.
- Genetic engineering: Altering DNA for medical and agricultural purposes.
- CRISPR: Gene-editing technology for precise DNA changes.
Genetic Disorders Review
- Autosomal dominant: Trait appears in every generation.
- Autosomal recessive: Trait can skip generations.
- X-linked traits: More common in males.
Cancer
- Cause: Uncontrolled cell growth due to mutations.
- Tumors: Benign (non-cancerous, non-spreading) or malignant (cancerous, spreading).
- Treatment: Surgery, chemotherapy, radiation.
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Description
Explore Mendel's foundational experiments on trait inheritance and the use of Punnett squares in genetics. This quiz covers dominant and recessive traits, genotype and phenotype ratios, as well as the concepts of homozygous and heterozygous conditions. Test your understanding of these key principles in genetic science.