Podcast
Questions and Answers
What primarily establishes the resting membrane potential in animal cells?
What primarily establishes the resting membrane potential in animal cells?
- Voltage-gated ion channels
- Active transport pumps
- Ligand-gated ion channels
- Leak channels (correct)
What is the typical resting membrane potential of an animal cell?
What is the typical resting membrane potential of an animal cell?
- -70 mV (correct)
- +60 mV
- 0 mV
- -90 mV
How does the movement of sodium ions (Na+) affect the membrane potential of a cell?
How does the movement of sodium ions (Na+) affect the membrane potential of a cell?
- It does not change the membrane potential
- It stabilizes the membrane at 0mV
- It makes the membrane potential more positive (correct)
- It makes the membrane potential more negative
Where is the concentration of sodium ions (Na+) typically higher?
Where is the concentration of sodium ions (Na+) typically higher?
What is the equilibrium potential of sodium ions (Na+)?
What is the equilibrium potential of sodium ions (Na+)?
Which of the following is a major function of Calcium ions ($Ca^{2+}$)?
Which of the following is a major function of Calcium ions ($Ca^{2+}$)?
If the membrane allows movement of sodium ions, what will occur?
If the membrane allows movement of sodium ions, what will occur?
Which of the following is NOT a function of Calcium ($Ca^{2+}$) ions?
Which of the following is NOT a function of Calcium ($Ca^{2+}$) ions?
What effect does the influx of $Ca^{2+}$ ions have on the membrane potential of an excitable cell?
What effect does the influx of $Ca^{2+}$ ions have on the membrane potential of an excitable cell?
Which of the following is NOT a typical stimulus for opening gated ion channels in excitable cells?
Which of the following is NOT a typical stimulus for opening gated ion channels in excitable cells?
What is the definition of depolarization in the context of membrane potential?
What is the definition of depolarization in the context of membrane potential?
Which of the following describes the primary function of voltage-gated ion channels?
Which of the following describes the primary function of voltage-gated ion channels?
What is the role of the initial stimulus in generating an action potential?
What is the role of the initial stimulus in generating an action potential?
In an action potential, why do the voltage-gated K+ channels open more slowly than the voltage-gated $Na^+$ channels?
In an action potential, why do the voltage-gated K+ channels open more slowly than the voltage-gated $Na^+$ channels?
What causes the inactivation of voltage-gated $Na^+$ channels during an action potential?
What causes the inactivation of voltage-gated $Na^+$ channels during an action potential?
During an action potential, which ion is primarily responsible for the repolarization phase?
During an action potential, which ion is primarily responsible for the repolarization phase?
What crucial role do voltage-gated $Ca^{2+}$ channels play at the axon terminals of neurons?
What crucial role do voltage-gated $Ca^{2+}$ channels play at the axon terminals of neurons?
What is a key characteristic of action potential propagation along the axon?
What is a key characteristic of action potential propagation along the axon?
Flashcards
Leak channels
Leak channels
A type of ion channel that is always open, allowing ions to passively move across the cell membrane according to their concentration gradients.
Resting membrane potential
Resting membrane potential
The electrical potential difference across the cell membrane when the cell is at rest. It is typically around -70 mV.
Sodium (Na+)
Sodium (Na+)
An ion crucial for cell function, with a higher concentration outside the cell.
Equilibrium potential of Na+
Equilibrium potential of Na+
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Calcium (Ca2+)
Calcium (Ca2+)
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Active transport
Active transport
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Passive transport
Passive transport
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Gated ion channels
Gated ion channels
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Excitable Cell
Excitable Cell
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Depolarization
Depolarization
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Hyperpolarization
Hyperpolarization
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Action Potential
Action Potential
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Threshold
Threshold
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Channel Inactivation
Channel Inactivation
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Dendrites
Dendrites
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Axon
Axon
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Axon Terminal
Axon Terminal
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Study Notes
Membrane Transport
- Membrane transport encompasses various processes that move substances across cell membranes
- Key factors involved in determining the direction of movement across the membrane are concentration and electrochemical gradients
- Membrane transport mechanisms: passive transport (osmosis, diffusion, facilitated diffusion), active transport (primary and secondary)
- Active Transport: Requires energy (ATP) to move substances against their concentration gradients
Ion Channels
- Ion channels are integral membrane proteins that form selective pathways for specific ions to pass through
- Leak channels: Continuously open and responsible for determining the resting membrane potential
- Gated channels: Open and close in response to specific stimuli (voltage-gated, ligand-gated, mechanically-gated)
- These channel types (leak, ligand-gated, mechanically-gated, and voltage-gated) are vital for cellular functions. Different gating mechanisms allow precise control of ion flow.
Resting Membrane Potential
- Resting membrane potential is the membrane potential of a cell in the absence of any stimuli
- It is typically around -70 mV in animal cells, indicating the inside of the cell is more negative than the outside, and it is crucial for cellular function.
- Leak channels play a major role in maintaining this potential.
Excitable Cells
- Excitable cells, like neurons and muscle cells, have the capacity to generate and conduct electrical signals known as action potentials
- Action potentials are rapid changes in membrane potential that allow for efficient communication between cells
Action Potential
- Action potentials are electrical events driven by the coordinated opening and closing of voltage-gated Na+ and K+ channels
- Initial stimulus depolarizes the membrane to the threshold potential, triggering a rapid influx of Na+ ions
- This creates the action potential spike.
Sodium Ions in Action Potential
- Sodium ions are essential to generate action potentials, rapidly entering the cell upon depolarization
- Sodium channels have inactivation mechanisms to prevent continued influx after rapid entry.
Calcium Ions and Neurotransmitter Release
- Calcium ions are vital for neurotransmitter release at synapses
- Action potentials trigger calcium influx into axon terminals initiating the exocytosis of neurotransmitters into the synaptic cleft.
Neurons
- Neurons are excitable cells that receive, process, and transmit information across long distances in the body
- Consisting of dendrites, cell body, axon, and axon terminals, allowing communication, integration, and control of numerous bodily functions
- Self-propagating action potentials along the axon, maintaining consistent magnitude and speed of signal transmission.
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Description
This quiz covers essential concepts of membrane transport processes and the role of ion channels in cellular functions. You'll explore mechanisms such as active and passive transport, as well as different types of ion channels and their gating mechanisms. Test your understanding of how these processes maintain cellular homeostasis.
