Podcast
Questions and Answers
What is the primary energy source for primary active transport?
What is the primary energy source for primary active transport?
The direct breakdown of ATP.
Describe the role of the Sodium-Potassium pump in cellular function.
Describe the role of the Sodium-Potassium pump in cellular function.
It exchanges three Na+ ions out of the cell for two K+ ions into the cell, maintaining the electrochemical gradient.
What distinguishes secondary active transport from primary active transport?
What distinguishes secondary active transport from primary active transport?
Secondary active transport uses the sodium concentration gradient created by the Na+-K+ ATPase pump for energy instead of direct ATP breakdown.
Give an example of a primary active transport process and explain how it functions.
Give an example of a primary active transport process and explain how it functions.
What is the role of carrier proteins in transport mechanisms?
What is the role of carrier proteins in transport mechanisms?
Explain the function of symport carriers in secondary active transport.
Explain the function of symport carriers in secondary active transport.
Identify an example of an antiport carrier and describe its mechanism.
Identify an example of an antiport carrier and describe its mechanism.
How does the conformational change in a carrier protein affect transport?
How does the conformational change in a carrier protein affect transport?
What is the significance of the sodium concentration gradient in secondary active transport?
What is the significance of the sodium concentration gradient in secondary active transport?
What is the main function of the sodium-potassium pump in cells?
What is the main function of the sodium-potassium pump in cells?
How does the calcium ATPase pump contribute to muscle relaxation?
How does the calcium ATPase pump contribute to muscle relaxation?
Describe the energy source used in secondary active transport.
Describe the energy source used in secondary active transport.
What is a symport carrier and provide an example?
What is a symport carrier and provide an example?
What role does ATP hydrolysis play in the function of primary active transport mechanisms?
What role does ATP hydrolysis play in the function of primary active transport mechanisms?
In the context of the resting membrane potential, what does it mean that the inside of the cell is negative relative to the outside?
In the context of the resting membrane potential, what does it mean that the inside of the cell is negative relative to the outside?
What is primary active transport and how does it differ from passive transport?
What is primary active transport and how does it differ from passive transport?
Explain how the sodium-potassium pump facilitates secondary active transport.
Explain how the sodium-potassium pump facilitates secondary active transport.
Describe the function of the sodium-potassium pump in cellular transport.
Describe the function of the sodium-potassium pump in cellular transport.
What is the role of the calcium ATPase pump in muscle contraction?
What is the role of the calcium ATPase pump in muscle contraction?
Explain secondary active transport and how it utilizes primary active transport.
Explain secondary active transport and how it utilizes primary active transport.
What are carrier proteins and what is their function in facilitated diffusion?
What are carrier proteins and what is their function in facilitated diffusion?
How do gated ion channels contribute to the selective permeability of the cell membrane?
How do gated ion channels contribute to the selective permeability of the cell membrane?
What is the significance of the transport maximum in facilitated diffusion?
What is the significance of the transport maximum in facilitated diffusion?
In what way does water solubility influence the mechanism of diffusion for different substances?
In what way does water solubility influence the mechanism of diffusion for different substances?
What role do ligands play in gated ion channels?
What role do ligands play in gated ion channels?
Flashcards
Primary Active Transport
Primary Active Transport
Movement of molecules across a membrane using energy from ATP hydrolysis, moving molecules against their concentration gradient.
Na+-K+ Pump
Na+-K+ Pump
A primary active transport protein that moves 3 sodium ions out of and 2 potassium ions into a cell, using one ATP molecule.
Secondary Active Transport
Secondary Active Transport
Movement of molecules across a membrane using energy from an existing ion gradient, rather than directly from ATP.
Symport Carrier
Symport Carrier
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Resting Membrane Potential (RMP)
Resting Membrane Potential (RMP)
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Calcium ATPase Pump
Calcium ATPase Pump
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H+-K+ Pump
H+-K+ Pump
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Antiport Carrier
Antiport Carrier
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Sodium-Glucose cotransporter
Sodium-Glucose cotransporter
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Sodium-Hydrogen Exchanger
Sodium-Hydrogen Exchanger
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Sodium-Calcium Exchanger
Sodium-Calcium Exchanger
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Glucose + Na+ transport
Glucose + Na+ transport
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Passive Transport
Passive Transport
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Diffusion Rate inverse relationship
Diffusion Rate inverse relationship
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Simple Diffusion
Simple Diffusion
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Facilitated Diffusion
Facilitated Diffusion
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Transport maximum
Transport maximum
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Diffusion through ion channels
Diffusion through ion channels
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Active Transport
Active Transport
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Study Notes
Transport Across Cell Membranes
- Importances of Ion Transport: Electrolytes (substances that dissociate in solution and conduct electricity) in extracellular and intracellular fluids (e.g., sodium, chloride, and potassium) are crucial for homeostasis.
- Passive Transport: Solutes move from high to low concentration gradients (downhill) without energy.
- Types: Simple diffusion (lipid-soluble molecules, water), facilitated diffusion (needs carrier proteins), and diffusion through ion channels (for charged molecules like ions).
- Active Transport: Solutes move against the concentration gradient (uphill) requiring energy ATP (Adenosine Triphosphate).
- Types: Primary active transport (e.g., sodium-potassium pump), secondary active transport (symport and antiport).
- Sodium-Potassium Pump: A primary active transport mechanism that moves 3 sodium ions out and 2 potassium ions into the cell, is crucial for maintaining cell volume and establishing resting membrane potential.
- Calcium ATPase Pump: A primary active transport pump is responsible for keeping intracellular calcium levels low, which is essential for muscle relaxation.
- Resting Membrane Potential: Difference in electric potential across the membrane. It is maintained primarily by the sodium-potassium pump and other factors.
- H+-K+ Pump: Location in stomach. Transports H+ ions out and K+ ions in, essential for HCL formation.
- Secondary Active Transport: Moves substances against their concentration gradient using the electrochemical gradient established by primary active transport (co-transport-symport/counter transport-antiport).
- Symport (Co-transport): Two substances are transported in the same direction across the membrane
- Antiport (Counter-transport): Two substances are transported in opposite directions across the membrane
- Carrier Proteins: Used in facilitated diffusion, and secondary active. These protein molecules aid the transport of large molecules across membranes.
- Ion Channels: Channels for charged particles (ions), which can be leakage (always open) or gated (opening/closing in response to signals like ligands or voltage changes).
- Ligand-gated channels: open when a signaling molecule (ligand) binds.
- Voltage-gated channels: respond to changes in membrane potential (voltage).
- Diffusion Rate Factors:
- Concentration gradient
- Lipid solubility
- Temperature
- Membrane permeability
- Membrane surface area
- Transport Maximum: A maximum amount of substance that can be transported per unit of time in facilitated diffusion. The maximum amount depends on the number and the activity of the carrier proteins.
- Transport Maximum affects: Hormones can also affect transport maximum.
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