Transport Across Cell Membranes Quiz
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Questions and Answers

What is the primary energy source for primary active transport?

The direct breakdown of ATP.

Describe the role of the Sodium-Potassium pump in cellular function.

It exchanges three Na+ ions out of the cell for two K+ ions into the cell, maintaining the electrochemical gradient.

What distinguishes secondary active transport from primary active transport?

Secondary active transport uses the sodium concentration gradient created by the Na+-K+ ATPase pump for energy instead of direct ATP breakdown.

Give an example of a primary active transport process and explain how it functions.

<p>The Calcium ATPase pump moves Ca++ ions out of the cell against their concentration gradient using ATP energy.</p> Signup and view all the answers

What is the role of carrier proteins in transport mechanisms?

<p>Carrier proteins facilitate the movement of specific molecules across the cell membrane by changing shape.</p> Signup and view all the answers

Explain the function of symport carriers in secondary active transport.

<p>Symport carriers transport two molecules in the same direction across the membrane, using the gradient of one molecule to drive the transport of another.</p> Signup and view all the answers

Identify an example of an antiport carrier and describe its mechanism.

<p>The Sodium-Hydrogen exchanger moves Na+ ions into the cell while transporting H+ ions out, maintaining pH balance.</p> Signup and view all the answers

How does the conformational change in a carrier protein affect transport?

<p>The conformational change allows the carrier to bind and release molecules on either side of the cell membrane, facilitating transport.</p> Signup and view all the answers

What is the significance of the sodium concentration gradient in secondary active transport?

<p>It provides the driving force necessary for the co-transport of other molecules against their concentration gradients.</p> Signup and view all the answers

What is the main function of the sodium-potassium pump in cells?

<p>The sodium-potassium pump maintains cell volume and contributes to resting membrane potential by pumping 3 sodium ions out and 2 potassium ions into the cell using one ATP.</p> Signup and view all the answers

How does the calcium ATPase pump contribute to muscle relaxation?

<p>The calcium ATPase pump keeps intracellular calcium levels low, which is essential for the relaxation of skeletal and cardiac muscle.</p> Signup and view all the answers

Describe the energy source used in secondary active transport.

<p>Secondary active transport utilizes the electrochemical gradients established by primary active transport as its energy source to move substances against their gradients.</p> Signup and view all the answers

What is a symport carrier and provide an example?

<p>A symport carrier is a type of cotransporter that moves two substances in the same direction; an example is the sodium-glucose cotransporter.</p> Signup and view all the answers

What role does ATP hydrolysis play in the function of primary active transport mechanisms?

<p>ATP hydrolysis provides the energy necessary for primary active transport mechanisms to move ions against their concentration gradients.</p> Signup and view all the answers

In the context of the resting membrane potential, what does it mean that the inside of the cell is negative relative to the outside?

<p>It means there is a higher concentration of positive ions outside the cell, leading to a net negative charge inside due to the activity of the sodium-potassium pump.</p> Signup and view all the answers

What is primary active transport and how does it differ from passive transport?

<p>Primary active transport moves molecules against their concentration gradient, requiring energy, while passive transport allows molecules to move down their gradient without energy input.</p> Signup and view all the answers

Explain how the sodium-potassium pump facilitates secondary active transport.

<p>The sodium-potassium pump creates a high concentration of sodium outside the cell, enabling the movement of sodium back into the cell to drive the transport of other substances like glucose against their gradient.</p> Signup and view all the answers

Describe the function of the sodium-potassium pump in cellular transport.

<p>The sodium-potassium pump actively transports sodium ions out of the cell and potassium ions into the cell, maintaining the cell's electrochemical gradient.</p> Signup and view all the answers

What is the role of the calcium ATPase pump in muscle contraction?

<p>The calcium ATPase pump removes calcium ions from the cytoplasm to the sarcoplasmic reticulum, allowing muscles to relax after contraction.</p> Signup and view all the answers

Explain secondary active transport and how it utilizes primary active transport.

<p>Secondary active transport uses the energy created by primary active transport to move other substances against their concentration gradient.</p> Signup and view all the answers

What are carrier proteins and what is their function in facilitated diffusion?

<p>Carrier proteins facilitate the transport of large water-soluble molecules across the cell membrane by binding to the substance and changing shape.</p> Signup and view all the answers

How do gated ion channels contribute to the selective permeability of the cell membrane?

<p>Gated ion channels open or close in response to specific signals, allowing selective passage of ions based on cellular needs.</p> Signup and view all the answers

What is the significance of the transport maximum in facilitated diffusion?

<p>The transport maximum represents the limit of how much substance can be transported per unit time based on the number and activity of carrier proteins.</p> Signup and view all the answers

In what way does water solubility influence the mechanism of diffusion for different substances?

<p>Water-soluble molecules require facilitated diffusion via carriers, while lipid-soluble molecules can easily pass through the membrane via simple diffusion.</p> Signup and view all the answers

What role do ligands play in gated ion channels?

<p>Ligands bind to ligand-gated ion channels, causing them to open or close and regulate ion flow across the membrane.</p> Signup and view all the answers

Flashcards

Primary Active Transport

Movement of molecules across a membrane using energy from ATP hydrolysis, moving molecules against their concentration gradient.

Na+-K+ Pump

A primary active transport protein that moves 3 sodium ions out of and 2 potassium ions into a cell, using one ATP molecule.

Secondary Active Transport

Movement of molecules across a membrane using energy from an existing ion gradient, rather than directly from ATP.

Symport Carrier

A type of carrier protein in secondary active transport that moves two or more substances in the same direction across the membrane.

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Resting Membrane Potential (RMP)

The difference in electrical potential across a cell membrane when it is not stimulated or actively transporting ions.

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Calcium ATPase Pump

Primary active transport protein that pumps calcium ions out of the cell or back into the sarcoplasmic reticulum, keeping intracellular calcium low.

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H+-K+ Pump

A primary active transport protein that pumps hydrogen ions out of and potassium ions into a cell, important for acid production.

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Antiport Carrier

Two molecules move in opposite directions across the membrane.

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Sodium-Glucose cotransporter

A symport carrier that moves sodium and glucose together into the cell.

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Sodium-Hydrogen Exchanger

An antiport carrier that exchanges sodium for hydrogen ions.

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Sodium-Calcium Exchanger

An antiport that exchanges sodium for calcium across a membrane.

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Glucose + Na+ transport

Glucose and Sodium bind to carrier protein, trigger conformational change for transport.

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Passive Transport

Movement of molecules across a membrane without energy input.

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Diffusion Rate inverse relationship

Diffusion speed is slower with larger molecules and thicker membranes.

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Simple Diffusion

Molecules move directly across the membrane (lipid-soluble or small water-soluble).

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Facilitated Diffusion

Large molecules use carrier proteins to cross membranes.

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Transport maximum

The highest rate at which facilitated diffusion can occur.

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Diffusion through ion channels

Ions move through specialized protein channels.

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Active Transport

Movement against the concentration gradient using energy (ATP).

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Study Notes

Transport Across Cell Membranes

  • Importances of Ion Transport: Electrolytes (substances that dissociate in solution and conduct electricity) in extracellular and intracellular fluids (e.g., sodium, chloride, and potassium) are crucial for homeostasis.
  • Passive Transport: Solutes move from high to low concentration gradients (downhill) without energy.
    • Types: Simple diffusion (lipid-soluble molecules, water), facilitated diffusion (needs carrier proteins), and diffusion through ion channels (for charged molecules like ions).
  • Active Transport: Solutes move against the concentration gradient (uphill) requiring energy ATP (Adenosine Triphosphate).
    • Types: Primary active transport (e.g., sodium-potassium pump), secondary active transport (symport and antiport).
  • Sodium-Potassium Pump: A primary active transport mechanism that moves 3 sodium ions out and 2 potassium ions into the cell, is crucial for maintaining cell volume and establishing resting membrane potential.
  • Calcium ATPase Pump: A primary active transport pump is responsible for keeping intracellular calcium levels low, which is essential for muscle relaxation.
  • Resting Membrane Potential: Difference in electric potential across the membrane. It is maintained primarily by the sodium-potassium pump and other factors.
  • H+-K+ Pump: Location in stomach. Transports H+ ions out and K+ ions in, essential for HCL formation.
  • Secondary Active Transport: Moves substances against their concentration gradient using the electrochemical gradient established by primary active transport (co-transport-symport/counter transport-antiport).
    • Symport (Co-transport): Two substances are transported in the same direction across the membrane
    • Antiport (Counter-transport): Two substances are transported in opposite directions across the membrane
  • Carrier Proteins: Used in facilitated diffusion, and secondary active. These protein molecules aid the transport of large molecules across membranes.
  • Ion Channels: Channels for charged particles (ions), which can be leakage (always open) or gated (opening/closing in response to signals like ligands or voltage changes).
    • Ligand-gated channels: open when a signaling molecule (ligand) binds.
    • Voltage-gated channels: respond to changes in membrane potential (voltage).
  • Diffusion Rate Factors:
    • Concentration gradient
    • Lipid solubility
    • Temperature
    • Membrane permeability
    • Membrane surface area
  • Transport Maximum: A maximum amount of substance that can be transported per unit of time in facilitated diffusion. The maximum amount depends on the number and the activity of the carrier proteins.
  • Transport Maximum affects: Hormones can also affect transport maximum.

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Membrane Transport 1 PDF

Description

Test your understanding of transport mechanisms across cell membranes. This quiz covers important concepts such as passive and active transport, types of ion transport, and the sodium-potassium pump. Challenge yourself to identify how substances move across membranes and their significance in maintaining homeostasis.

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