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Questions and Answers
What distinguishes CFTR from other ABC transporters?
What distinguishes CFTR from other ABC transporters?
- It is the only ABC transporter that is also an ion channel (correct)
- It is the only ligand-gated channel that does not consume its ligand
- It is involved in excretion of toxins from cells
- It consumes its ligand (ATP) during the gating cycle
What drives active transport and can cause several diseases if dysfunctional?
What drives active transport and can cause several diseases if dysfunctional?
- Oligosaccharide chains
- PKAa cAMP PKAj
- (NH2) Chloride Channel
- ATP hydrolysis (correct)
What causes Menkes disease (syndrome)?
What causes Menkes disease (syndrome)?
- Impaired intestinal transport of copper
- Defects in CFTR
- Defects in copper ion transporters ATP7A and 7B
- Mutations in genes coding for ATP7A (correct)
What genetic defects lead to Cystic Fibrosis (CF) disease?
What genetic defects lead to Cystic Fibrosis (CF) disease?
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What is the function of P-glycoprotein?
What is the function of P-glycoprotein?
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