Membrane Transport and Action Potentials
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Questions and Answers

What distinguishes CFTR from other ABC transporters?

  • It is the only ABC transporter that is also an ion channel (correct)
  • It is the only ligand-gated channel that does not consume its ligand
  • It is involved in excretion of toxins from cells
  • It consumes its ligand (ATP) during the gating cycle
  • What drives active transport and can cause several diseases if dysfunctional?

  • Oligosaccharide chains
  • PKAa cAMP PKAj
  • (NH2) Chloride Channel
  • ATP hydrolysis (correct)
  • What causes Menkes disease (syndrome)?

  • Impaired intestinal transport of copper
  • Defects in CFTR
  • Defects in copper ion transporters ATP7A and 7B
  • Mutations in genes coding for ATP7A (correct)
  • What genetic defects lead to Cystic Fibrosis (CF) disease?

    <p>Defects in CFTR</p> Signup and view all the answers

    What is the function of P-glycoprotein?

    <p>Involved in the excretion of toxins from cells</p> Signup and view all the answers

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