Membrane Proteins Overview

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Questions and Answers

Which type of protein is responsible for most of the membrane's specific tasks?

  • Membrane transport proteins
  • Transmembrane proteins (correct)
  • Intracellular signaling proteins
  • Cell-surface receptors

In which type of membrane will you find about 75% protein by mass?

  • Plasma membrane
  • Intracellular signaling protein membrane
  • Cell-surface receptor membrane
  • Myelin membrane (correct)

Which type of protein is most likely to be involved in ATP production?

  • Intracellular signaling proteins
  • Transmembrane proteins
  • Cell-surface receptors
  • Membrane transport proteins (correct)

What is the approximate ratio of lipid molecules to protein molecules in cell membranes that are 50% protein by mass?

<p>50:1 (D)</p> Signup and view all the answers

Which type of proteins vary widely in structure and function reflecting their diverse roles?

<p>Transmembrane proteins (B)</p> Signup and view all the answers

Where are transmembrane proteins located?

<p>Extend through the lipid bilayer (B)</p> Signup and view all the answers

Which type of membrane proteins are associated with the lipid bilayer only by a covalent linkage to a lipid anchor in the outer monolayer of the plasma membrane?

<p>Cell-surface receptors (A)</p> Signup and view all the answers

Which proteins can function on both sides of the lipid bilayer or transport molecules across it?

<p>Transmembrane proteins (A)</p> Signup and view all the answers

How are some intracellular signaling proteins associated with the cytosolic half of the plasma membrane?

<p>By covalently attached lipid chains (A)</p> Signup and view all the answers

Which proteins are bound to either face of the membrane by noncovalent interactions with other membrane proteins?

<p>Peripheral membrane proteins (B)</p> Signup and view all the answers

How do some proteins associate with membranes in a classical manner?

<p>Through regulated protein-protein interactions (C)</p> Signup and view all the answers

What happens to small GTPases of the Rab protein family in their GTP-bound state?

<p>Their lipid anchor is exposed and tethers them to membranes (D)</p> Signup and view all the answers

Where are sugar residues added to many membrane proteins?

<p>In the lumen of ER and the Golgi apparatus (C)</p> Signup and view all the answers

Where are oligosaccharide chains typically present on a single pass transmembrane protein?

<p>On the noncytosolic side of the membrane (C)</p> Signup and view all the answers

Why do sulfhydryl groups in the cytosolic domain of membrane proteins not normally form disulfide bonds?

<p>The reducing environment in the cytosol maintains these groups in their reduced (-SH) form (D)</p> Signup and view all the answers

What does the carbohydrate layer on the cell surface mainly consist of?

<p>Oligosaccharide side chains of membrane glycolipids and membrane glycoproteins (A)</p> Signup and view all the answers

What does a thick carbohydrate-rich layer surrounding a lymphocyte in an electron micrograph indicate?

<p>Presence of a carbohydrate layer on the cell surface (C)</p> Signup and view all the answers

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