Membrane Transport and Lipid Bilayer Quiz
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Questions and Answers

What does the Na+/K+-ATPase pump do?

  • Pumps K+ ions in and Na+ ions out
  • Pumps Na+ ions in and K+ ions out
  • Pumps K+ ions out and Na+ ions in
  • Pumps Na+ ions out and K+ ions in (correct)
  • Which molecule-specific transmembrane protein is usually called 'pumps'?

  • Na+/K+-ATPase (correct)
  • Na+/glucose cotransporter
  • Na+/H+ exchanger
  • Glucose transporter
  • What is the purpose of the Na+/K+-ATPase pump?

  • To establish steep gradients needed for nerve-muscle impulses
  • To keep external Na+ high
  • To keep internal Na+ low (correct)
  • To maintain the overall charge of the cell
  • What is the net charge on each side of the membrane as the Na+/K+-ATPase pump operates?

    <p>The cell interior becomes more negative</p> Signup and view all the answers

    What is the rate at which the Na+/K+-ATPase pump operates?

    <p>~100 cycles/sec</p> Signup and view all the answers

    How much energy does the Na+/K+-ATPase pump use in most animal cells?

    <p>1/3</p> Signup and view all the answers

    What does the Na+/glucose cotransporter use to drive the import of glucose?

    <p>The electrochemical Na+ gradient</p> Signup and view all the answers

    How many Na+ ions bind to the Na+/glucose cotransporter on the outer apical surface?

    <p>2</p> Signup and view all the answers

    How many moles of Na+ ions need to move into a cell to generate a glucose concentration that is 30,000 times higher inside than outside?

    <p>2</p> Signup and view all the answers

    What is the movement of Na+ and glucose across the apical membrane an example of?

    <p>Secondary active transport</p> Signup and view all the answers

    Which of the following is true about the lipid bilayer?

    <p>It prevents loss of charged and polar solutes</p> Signup and view all the answers

    What determines the rate of simple diffusion across protein-free bilayer membranes?

    <p>Size and solubility</p> Signup and view all the answers

    Which statement about the permeability of membranes to water and small ions is true?

    <p>Membranes are more permeable to water than to small ions</p> Signup and view all the answers

    What is the main electrical effect of tiny excesses of charges near the plasma membrane?

    <p>They create an electrochemical gradient</p> Signup and view all the answers

    What are the two components of an electrochemical gradient?

    <p>Chemical and electrical</p> Signup and view all the answers

    Which process allows substances to move from a region of high concentration to a region of low concentration?

    <p>Facilitated diffusion</p> Signup and view all the answers

    What is the main driving force for diffusion?

    <p>Random thermal motion</p> Signup and view all the answers

    What are the two means for movement across a selectively permeable membrane?

    <p>Simple diffusion and active transport</p> Signup and view all the answers

    What is the characteristic set of carrier proteins for each cell membrane?

    <p>Membrane transporters</p> Signup and view all the answers

    What are the two types of transporters and channels involved in facilitated diffusion?

    <p>Carrier proteins and ion channels</p> Signup and view all the answers

    Which process allows substances to move across membranes by directly passing through the lipid bilayer?

    <p>Simple diffusion through lipid bilayer</p> Signup and view all the answers

    Which type of transport uses protein-lined channels to facilitate the movement of substances across membranes?

    <p>Facilitated transport through aqueous, protein-lined channel</p> Signup and view all the answers

    Which type of transport involves membrane-spanning proteins that change shape to facilitate the movement of substances across membranes?

    <p>Facilitated transporters</p> Signup and view all the answers

    Which type of transport requires energy to move molecules against their concentration gradient?

    <p>Active transport</p> Signup and view all the answers

    Which category of ion channels opens due to a change in voltage difference across the membrane?

    <p>Voltage-gated channels</p> Signup and view all the answers

    Which category of ion channels opens due to the binding of a specific ligand, usually not the transported species?

    <p>Ligand-gated channels</p> Signup and view all the answers

    Which category of ion channels opens due to mechanical stimulation, such as pressure or stretch?

    <p>Stress-gated channels</p> Signup and view all the answers

    Which type of transporter allows facilitated diffusion of glucose into muscle cells down its concentration gradient?

    <p>Glucose transporter</p> Signup and view all the answers

    Which transporter is regulated by insulin and is responsible for glucose uptake into various cells?

    <p>Glucose transporter</p> Signup and view all the answers

    Which type of transport uses energy to move molecules against their concentration gradient?

    <p>Active transport</p> Signup and view all the answers

    Diffusion of ions through membrane channels transport is ______ and proceeds down the concentration gradient of the ion being transported

    <p>passive</p> Signup and view all the answers

    Major categories of gated ion channels: 1. Voltage-gated channels -- opens due to change in ______ difference

    <p>voltage</p> Signup and view all the answers

    Glucose transporter -- facilitated diffusion of ______ into muscle cell down concentration gradient (High --> Low)

    <p>glucose</p> Signup and view all the answers

    Active transport uses ______ to move molecules 'up' conc. gradient (Low --> High)

    <p>energy</p> Signup and view all the answers

    Na+/K+-ATPase pump changes shape when ________

    <p>autophosphorylated</p> Signup and view all the answers

    The Na+/K+-ATPase pump pumps ________ ions out and ________ ions in

    <p>Na+, K+</p> Signup and view all the answers

    The Na+/glucose cotransporter binds ________ Na+ ions and ________ glucose molecule(s) on the outer apical surface

    <p>2, 1</p> Signup and view all the answers

    Movement of ________ moles of Na+ ions into a cell can generate a glucose concentration that is 30,000 times higher inside than out

    <p>2</p> Signup and view all the answers

    Membranes are a billion times more permeable to water than to small ions Fig. 12-2 Inside Outside Approximately equal quantities of +/- charges inside and outside of cell Tiny excesses of + or - charges do occur near PM and have imp. electrical effects Table 12-1 Remember a salty banana Na+______ClK+

    <p>Each cell membrane has its own characteristic set of carrier proteins Figure 12-8 Transporters and channels move inorganic ions and small, polar molecules cross membrane — facilitated diffusion A — channels either open or close; faster transport rates than transporters B — transporters undergo a series of conformational changes (alternate access) Fig. 12-3 Membranes are a selectively permeable barrier - two means for movement both of which lead to net flux of ions/compounds (influx - into cell; efflux out of cell) 1. Passively by diffusion 2. Actively by energy-coupled transport process Diffusion substance moves from region of high conc. to region of low conc.; eventually eliminating conc. difference driven by random thermal motion leading to increase in entropy electrochemical gradient --chemical - compartment concentration difference -- electrical - compartment charge difference An electrochemical gradient has two components Width of green arrow -- magnitude of gradient Fig. 12-5 Different processes by which substances move across membranes 1. Simple diffusion through lipid bilayer 2.</p> Signup and view all the answers

    Membranes are a billion times more permeable to water than to small ions Fig. 12-2 Inside Outside Approximately equal quantities of +/- charges inside and outside of cell Tiny excesses of + or - charges do occur near PM and have imp. electrical effects Table 12-1 Remember a salty banana Na+Cl______+

    <p>K+</p> Signup and view all the answers

    Membranes are a billion times more permeable to water than to small ions Fig. 12-2 Inside Outside Approximately equal quantities of +/- charges inside and outside of cell Tiny excesses of + or - charges do occur near PM and have imp. electrical effects Table 12-1 Remember a salty banana ______ClK+

    <p>Na+</p> Signup and view all the answers

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