Memantine

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Questions and Answers

What is the peak action time of Memantine?

  • 3 to 12 hours (correct)
  • More than 72 hours
  • 24 to 48 hours
  • 1 to 2 hours

How is Memantine excreted from the body?

  • Renally (correct)
  • Through lungs
  • Through sweat
  • Through bile

What is the terminal elimination half-life of Memantine?

  • 60 to 80 hours (correct)
  • More than 100 hours
  • 12 to 24 hours
  • 24 to 36 hours

What is the primary action of Donepezil hydrochloride?

<p>Enhances acetylcholine uptake in the brain (C)</p> Signup and view all the answers

When is Donepezil hydrochloride usually taken?

<p>At bedtime each day (A)</p> Signup and view all the answers

What is a common adverse effect of Donepezil hydrochloride?

<p>Headache (A)</p> Signup and view all the answers

What labs should be monitored if GI bleeding is suspected in a patient taking Donepezil hydrochloride?

<p>Complete blood count and bleeding time (A)</p> Signup and view all the answers

What is the primary action of Memantine in Alzheimer's disease?

<p>Prevents neuronal cell death by acting on glutamate receptors (C)</p> Signup and view all the answers

What is a contraindication for the use of Memantine?

<p>Renal failure (B)</p> Signup and view all the answers

When is the combination of Donepezil and Memantine available for patients?

<p>Stabilized on 10 mg donepezil once daily but not taking memantine (C)</p> Signup and view all the answers

What is the primary effect of Donepezil hydrochloride on acetylcholine?

<p>Inhibits the metabolism, leading to elevated levels in the cortex (D)</p> Signup and view all the answers

What is a potential GI-related adverse effect of Donepezil hydrochloride?

<p>Nausea (A)</p> Signup and view all the answers

Which drug is indicated for mild to moderate dementia due to Alzheimer's disease and Parkinson's disease?

<p>Rivastigmine tartrate (C)</p> Signup and view all the answers

What is a contraindication for the use of Donepezil?

<p>Hypersensitivity to the drug, lung disease, and heart disease such as sick sinus syndrome (C)</p> Signup and view all the answers

What can increase the effects of Donepezil?

<p>Theophylline and cholinesterase inhibitors (C)</p> Signup and view all the answers

How long does the peak of action occur after oral administration of Donepezil?

<p>3 to 8 hours (C)</p> Signup and view all the answers

Where does the metabolism of Rivastigmine tartrate occur?

<p>Liver (B)</p> Signup and view all the answers

What is a common adverse effect of Galantamine Hydrobromide?

<p>Insomnia (C)</p> Signup and view all the answers

When is Rabeprazole taken?

<p>At bedtime (D)</p> Signup and view all the answers

What should nurses assess for before administering Donepezil?

<p>Allergy, orientation, and contraindications (B)</p> Signup and view all the answers

What is a common GI-related adverse effect of Donepezil?

<p>GI bleeding (A)</p> Signup and view all the answers

What is the excretion route of Donepezil and its metabolites?

<p>Urine (C)</p> Signup and view all the answers

What is a contraindication for the use of Galantamine Hydrobromide?

<p>Severe hepatic or renal impairment (D)</p> Signup and view all the answers

What is the recommended duration of treatment with Rivastigmine tartrate?

<p>12 months (C)</p> Signup and view all the answers

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