Memantine
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Questions and Answers

What is the peak action time of Memantine?

  • 3 to 12 hours (correct)
  • More than 72 hours
  • 24 to 48 hours
  • 1 to 2 hours
  • How is Memantine excreted from the body?

  • Renally (correct)
  • Through lungs
  • Through sweat
  • Through bile
  • What is the terminal elimination half-life of Memantine?

  • 60 to 80 hours (correct)
  • More than 100 hours
  • 12 to 24 hours
  • 24 to 36 hours
  • What is the primary action of Donepezil hydrochloride?

    <p>Enhances acetylcholine uptake in the brain</p> Signup and view all the answers

    When is Donepezil hydrochloride usually taken?

    <p>At bedtime each day</p> Signup and view all the answers

    What is a common adverse effect of Donepezil hydrochloride?

    <p>Headache</p> Signup and view all the answers

    What labs should be monitored if GI bleeding is suspected in a patient taking Donepezil hydrochloride?

    <p>Complete blood count and bleeding time</p> Signup and view all the answers

    What is the primary action of Memantine in Alzheimer's disease?

    <p>Prevents neuronal cell death by acting on glutamate receptors</p> Signup and view all the answers

    What is a contraindication for the use of Memantine?

    <p>Renal failure</p> Signup and view all the answers

    When is the combination of Donepezil and Memantine available for patients?

    <p>Stabilized on 10 mg donepezil once daily but not taking memantine</p> Signup and view all the answers

    What is the primary effect of Donepezil hydrochloride on acetylcholine?

    <p>Inhibits the metabolism, leading to elevated levels in the cortex</p> Signup and view all the answers

    What is a potential GI-related adverse effect of Donepezil hydrochloride?

    <p>Nausea</p> Signup and view all the answers

    Which drug is indicated for mild to moderate dementia due to Alzheimer's disease and Parkinson's disease?

    <p>Rivastigmine tartrate</p> Signup and view all the answers

    What is a contraindication for the use of Donepezil?

    <p>Hypersensitivity to the drug, lung disease, and heart disease such as sick sinus syndrome</p> Signup and view all the answers

    What can increase the effects of Donepezil?

    <p>Theophylline and cholinesterase inhibitors</p> Signup and view all the answers

    How long does the peak of action occur after oral administration of Donepezil?

    <p>3 to 8 hours</p> Signup and view all the answers

    Where does the metabolism of Rivastigmine tartrate occur?

    <p>Liver</p> Signup and view all the answers

    What is a common adverse effect of Galantamine Hydrobromide?

    <p>Insomnia</p> Signup and view all the answers

    When is Rabeprazole taken?

    <p>At bedtime</p> Signup and view all the answers

    What should nurses assess for before administering Donepezil?

    <p>Allergy, orientation, and contraindications</p> Signup and view all the answers

    What is a common GI-related adverse effect of Donepezil?

    <p>GI bleeding</p> Signup and view all the answers

    What is the excretion route of Donepezil and its metabolites?

    <p>Urine</p> Signup and view all the answers

    What is a contraindication for the use of Galantamine Hydrobromide?

    <p>Severe hepatic or renal impairment</p> Signup and view all the answers

    What is the recommended duration of treatment with Rivastigmine tartrate?

    <p>12 months</p> Signup and view all the answers

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