Melatonin Receptor Agonists: Ramelteon and MOA
17 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main function of the suprachiasmatic nucleus in the brain?

  • Controlling the circadian pacemaker (correct)
  • Increasing withdrawal symptoms
  • Inducing rebound insomnia
  • Regulating GABAergic neurotransmission
  • Which receptors does Ramelteon act on?

  • Orexin receptors
  • GABA receptors
  • Cholinergic receptors
  • MT1 and MT2 melatonin receptors (correct)
  • What distinguishes Ramelteon's effects on sleep architecture from other drugs?

  • Increases withdrawal symptoms
  • Alters GABAergic neurotransmission
  • Causes rebound insomnia
  • Reduces persistent sleep latency (correct)
  • Which peptides are involved in the control of wakefulness?

    <p>Orexin A &amp; B</p> Signup and view all the answers

    What effect does loss of orexin neurons have on the body?

    <p>Results in narcolepsy</p> Signup and view all the answers

    Which disorder is Suvorexant used to treat?

    <p>Insomnia</p> Signup and view all the answers

    Which receptor does melatonin bind to promote the onset of sleep?

    <p>MT1</p> Signup and view all the answers

    What is the function of the suprachiasmatic nucleus?

    <p>Coordinates circadian rhythms</p> Signup and view all the answers

    Which neurotransmitter system does suvorexant target?

    <p>Orexin</p> Signup and view all the answers

    What is the primary indication for the use of ramelteon?

    <p>Long-term treatment of insomnia</p> Signup and view all the answers

    Which drug is known for its longer half-life and causing less amnesia compared to zolpidem or benzodiazepines?

    <p>Eszopiclone</p> Signup and view all the answers

    Which category is most benzodiazepines and barbiturates classified under in terms of teratogenicity?

    <p>Category D</p> Signup and view all the answers

    Which of the following drugs is classified as category C in terms of teratogenicity?

    <p>Zaleplon</p> Signup and view all the answers

    What is the half-life of flumazenil due to rapid hepatic clearance?

    <p>0.7–1.3 hours</p> Signup and view all the answers

    Flumazenil acts as a competitive antagonist with high affinity to which receptors?

    <p>Benzodiazepine receptors</p> Signup and view all the answers

    Which drug is used to block the effect of benzodiazepines only, not barbiturates, ethanol, or opioids?

    <p>Flumazenil</p> Signup and view all the answers

    Which class of drugs can lead to enhanced CNS depression due to interactions with sedative-hypnotics?

    <p>Antihistamines</p> Signup and view all the answers

    More Like This

    Melatonin and Sleep Patterns Quiz
    2 questions

    Melatonin and Sleep Patterns Quiz

    WellEstablishedMoldavite avatar
    WellEstablishedMoldavite
    Ramelteon and Circadian Rhythms
    18 questions
    Ramelton (Rozerem) Flashcards
    9 questions
    Melatonin Flashcards
    8 questions

    Melatonin Flashcards

    EnthralledSaxhorn avatar
    EnthralledSaxhorn
    Use Quizgecko on...
    Browser
    Browser