Meiosis: Genetic Variation

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Questions and Answers

Which of the following events contributes most significantly to genetic variation during meiosis?

  • Crossing over between homologous chromosomes during prophase I. (correct)
  • The replication of DNA during interphase before meiosis I.
  • The alignment of chromosomes at the metaphase plate during metaphase II.
  • The separation of sister chromatids during anaphase II.

During which stage of meiosis does independent assortment of chromosomes occur, leading to genetic variation?

  • Prophase I
  • Telophase II
  • Metaphase I (correct)
  • Anaphase II

How does anaphase I of meiosis differ from anaphase of mitosis?

  • In meiosis I, the chromosome number is halved, while in mitosis, it doubles.
  • In meiosis I, sister chromatids separate, while in mitosis, homologous chromosomes separate.
  • In meiosis I, homologous chromosomes separate, while in mitosis, sister chromatids separate. (correct)
  • In meiosis I, the chromosome number doubles, while in mitosis, it remains the same.

Which of the following is the correct sequence of events during prophase I of meiosis?

<p>Leptotene, zygotene, pachytene, diplotene, diakinesis (C)</p> Signup and view all the answers

What is the direct outcome of meiosis I?

<p>Two haploid cells with duplicated chromosomes. (D)</p> Signup and view all the answers

What is the significance of chiasmata formation during meiosis?

<p>They are the sites where homologous chromosomes exchange genetic material. (D)</p> Signup and view all the answers

Which of the following events takes place during anaphase II?

<p>Sister chromatids separate and move toward opposite poles. (B)</p> Signup and view all the answers

If a cell with 20 chromosomes undergoes meiosis, how many chromosomes will each daughter cell have at the end of meiosis II?

<p>10 (A)</p> Signup and view all the answers

Which of the following is a key difference between meiosis I and meiosis II?

<p>DNA replication occurs before meiosis I, but not before meiosis II. (D)</p> Signup and view all the answers

The synaptonemal complex forms during which stage of meiosis I?

<p>Zygotene (A)</p> Signup and view all the answers

Flashcards

Meiosis

A specialized cell division halving chromosome number to create four unique haploid cells, essential for sexual reproduction.

Independent assortment

Random alignment of homologous chromosome pairs during metaphase I, creating diverse maternal/paternal chromosome combinations in daughter cells.

Crossing over

Exchange of genetic material between homologous chromosomes during prophase I, creating new allele combinations.

Random fertilization

Any sperm can fuse with any egg during fertilization, increasing genetic diversity in offspring.

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Zygotene

Homologous chromosomes pair up in a process called synapsis, forming a synaptonemal complex.

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Pachytene

Homologous chromosomes exchange genetic material at chiasmata.

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Metaphase I

Homologous chromosome pairs align at the metaphase plate during Metaphase I.

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Anaphase I

Homologous chromosomes separate and move toward opposite poles; sister chromatids remain attached.

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Anaphase II

Sister chromatids separate and move toward opposite poles during Meiosis II.

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Telophase II and Cytokinesis

Four haploid daughter cells, each with unduplicated chromosomes, are the result of this stage of meiosis.

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Study Notes

  • Meiosis is a specialized type of cell division that reduces the chromosome number by half, resulting in four haploid cells, each genetically distinct from the parent cell
  • Essential for sexual reproduction, maintaining a stable chromosome number across generations
  • Meiosis consists of two successive nuclear and cellular divisions: Meiosis I and Meiosis II

Genetic Variation

  • Meiosis introduces genetic variation through mechanisms like independent assortment, crossing over, and random fertilization
    • Independent assortment: During metaphase I, homologous chromosome pairs align randomly, leading to different combinations of maternal and paternal chromosomes in daughter cells
    • Crossing over: Occurs in prophase I, where homologous chromosomes exchange genetic material at the chiasmata, creating recombinant chromosomes
    • Random fertilization: Any sperm can fuse with any egg, further increasing genetic diversity
    • These mechanisms result in offspring with unique combinations of genes, contributing to diversity within populations

Stages of Meiosis I

Prophase I

  • The most complex phase, accounting for about 90% of the time required for meiosis
  • Subdivided into stages:
    • Leptotene: Chromosomes begin to condense and become visible
    • Zygotene: Homologous chromosomes pair up (synapsis), forming a synaptonemal complex
    • Pachytene: Crossing over occurs; homologous chromosomes exchange genetic material at chiasmata
    • Diplotene: Synaptonemal complex disassembles; homologous chromosomes remain connected at chiasmata
    • Diakinesis: Chromosomes fully condense, and the nuclear envelope breaks down

Metaphase I

  • Homologous chromosome pairs align at the metaphase plate
  • Microtubules from opposite poles attach to the kinetochores of each homologous chromosome

Anaphase I

  • Homologous chromosomes separate and move toward opposite poles; sister chromatids remain attached
  • Differs from mitosis, where sister chromatids separate

Telophase I and Cytokinesis

  • Chromosomes arrive at opposite poles
  • Nuclear envelope may reform
  • Cytokinesis occurs, resulting in two haploid daughter cells, each with duplicated chromosomes

Stages of Meiosis II

Prophase II

  • Chromosomes condense
  • Nuclear envelope breaks down (if reformed in Telophase I)

Metaphase II

  • Sister chromatids align at the metaphase plate
  • Microtubules from opposite poles attach to the kinetochores of each sister chromatid

Anaphase II

  • Sister chromatids separate and move toward opposite poles

Telophase II and Cytokinesis

  • Chromosomes arrive at opposite poles
  • Nuclear envelope reforms
  • Cytokinesis occurs, resulting in four haploid daughter cells, each with unduplicated chromosomes

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