Meglitinides Overview and Medications
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Questions and Answers

Which class of anti-diabetic drugs stimulate the release of insulin from the pancreas, can lead to hypoglycemia, and must be given before meals?

  • Meglitinides (correct)
  • Sulfonylureas
  • Biguanides
  • Thiazolidinediones

What may benefit a patient with sulfa allergy and elevated post prandial glucose?

Meglitinides such as repaglinide (Prandin) and nateglinide (Starlix).

Meglitinides are helpful for which type of glucose elevations?

Post-prandial

Would a patient with inflammatory bowel disease be a good candidate for therapy with a meglitinide?

<p>False (B)</p> Signup and view all the answers

Study Notes

Meglitinides Overview

  • Meglitinides are a class of anti-diabetic drugs that stimulate insulin release from the pancreas.
  • These medications can result in hypoglycemia if not monitored properly.
  • Meglitinides must be taken before meals to optimize their effectiveness.

Specific Medications

  • Key meglitinides include:
    • Repaglinide (trade name: Prandin)
    • Nateglinide (trade name: Starlix)

Targeted Use

  • Meglitinides are particularly effective for controlling post-prandial (after meal) glucose elevations.
  • Recommended for patients with sulfa allergies who experience elevated post-prandial glucose levels.

Cautions and Contraindications

  • Not advisable for patients with inflammatory bowel disease, indicating potential contraindications or risks.

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Description

This quiz explores the class of anti-diabetic drugs known as meglitinides, which enhance insulin release from the pancreas. You'll learn about key medications like Repaglinide and Nateglinide, their effectiveness in managing post-prandial glucose, and important precautions for their use.

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