Podcast
Questions and Answers
Which class of anti-diabetic drugs stimulate the release of insulin from the pancreas, can lead to hypoglycemia, and must be given before meals?
What may benefit a patient with sulfa allergy and elevated post prandial glucose?
Meglitinides such as repaglinide (Prandin) and nateglinide (Starlix).
Meglitinides are helpful for which type of glucose elevations?
Post-prandial
Would a patient with inflammatory bowel disease be a good candidate for therapy with a meglitinide?
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Study Notes
Meglitinides Overview
- Meglitinides are a class of anti-diabetic drugs that stimulate insulin release from the pancreas.
- These medications can result in hypoglycemia if not monitored properly.
- Meglitinides must be taken before meals to optimize their effectiveness.
Specific Medications
- Key meglitinides include:
- Repaglinide (trade name: Prandin)
- Nateglinide (trade name: Starlix)
Targeted Use
- Meglitinides are particularly effective for controlling post-prandial (after meal) glucose elevations.
- Recommended for patients with sulfa allergies who experience elevated post-prandial glucose levels.
Cautions and Contraindications
- Not advisable for patients with inflammatory bowel disease, indicating potential contraindications or risks.
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Description
This quiz explores the class of anti-diabetic drugs known as meglitinides, which enhance insulin release from the pancreas. You'll learn about key medications like Repaglinide and Nateglinide, their effectiveness in managing post-prandial glucose, and important precautions for their use.