Medulla Oblongata Structure and Function
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Questions and Answers

The medulla oblongata extends from the pons to the spinal cord.

True (A)

The facial nerve (VII) emerges between the pons and the anterior median fissure.

False (B)

The hypoglossal trigone is located lateral to the vagal trigone on the floor of the fourth ventricle.

False (B)

The inferior cerebellar peduncle connects the medulla oblongata to the cerebellum.

<p>True (A)</p> Signup and view all the answers

The pyramids of the medulla contain corticothalamic fibers.

<p>False (B)</p> Signup and view all the answers

The vallecula of the cerebrum embraces the medulla oblongata dorsally.

<p>False (B)</p> Signup and view all the answers

The 'open part' of the medulla contains the upward continuation of the central canal of the spinal cord.

<p>False (B)</p> Signup and view all the answers

The trigeminal tubercle is always a well-defined elevation on the dorsal surface of the closed part of the medulla.

<p>False (B)</p> Signup and view all the answers

The abducens nerve (VI) emerges between the pons and the olive.

<p>False (B)</p> Signup and view all the answers

The gracile and cuneate tubercles are located dorsally in the lower medulla.

<p>True (A)</p> Signup and view all the answers

The rootlets of the ninth, tenth and cranial part of the eleventh nerves emerge lateral to the olive.

<p>True (A)</p> Signup and view all the answers

The hypoglossal nucleus is located under the dorsal trigone.

<p>False (B)</p> Signup and view all the answers

The dorsal nucleus of the vagus contains motor cell bodies for skeletal muscle.

<p>False (B)</p> Signup and view all the answers

The cells of the nucleus of the tractus solitarius are the most loosely packed of any brainstem nucleus.

<p>False (B)</p> Signup and view all the answers

The nucleus ambiguus contains motor cell bodies for muscles of the larynx, soft palate, pharynx, and upper esophagus, all distributed by branches of the vagus nerve, aside from the supply to stylopharyngeus, which is innervated by the facial nerve.

<p>False (B)</p> Signup and view all the answers

The spinal nucleus and tract of the trigeminal nerve lie medial to the nucleus of the tractus solitarius.

<p>False (B)</p> Signup and view all the answers

The inferior olivary nucleus fibers (olivocerebellar) decussate across the midline to enter the superior cerebellar peduncle.

<p>False (B)</p> Signup and view all the answers

The gracile and cuneate nuclei give origin to the spinal lemniscus.

<p>False (B)</p> Signup and view all the answers

The accessory cuneate nucleus conveys proprioceptive impulses from the upper limb to the cerebellum via the superior peduncle.

<p>False (B)</p> Signup and view all the answers

The medullary reticular formation is located primarily between the pyramids and the floor of the fourth ventricle.

<p>False (B)</p> Signup and view all the answers

The cardiac, respiratory, and vasomotor centers are anatomically demonstrable as distinct nuclei within the reticular formation.

<p>False (B)</p> Signup and view all the answers

The area postrema, located near the gracile nuclei, is protected by the blood-brain barrier.

<p>False (B)</p> Signup and view all the answers

The brainstem reticular formation is only responsible for motor activity.

<p>False (B)</p> Signup and view all the answers

The reticulospinal tracts, originating from the reticular formation cells, are part of the pyramidal system.

<p>False (B)</p> Signup and view all the answers

The medulla is supplied ventrally by branches of the vertebral and basilar arteries.

<p>True (A)</p> Signup and view all the answers

Damage to the anterior spinal artery results in paralysis of the tongue on the opposite side.

<p>False (B)</p> Signup and view all the answers

Dysphonia and dysphagia result from damage to the spinal lemniscus.

<p>False (B)</p> Signup and view all the answers

Damage to the vestibular nuclei results in anosmia.

<p>False (B)</p> Signup and view all the answers

The medial medullary syndrome includes hemiplegia on the same side as the lesion.

<p>False (B)</p> Signup and view all the answers

Reticular formation cells do not receive input from the hypothalamus.

<p>False (B)</p> Signup and view all the answers

Flashcards

Medulla Oblongata

A structure in the brainstem that connects the pons and spinal cord.

Closed Part of Medulla

The lower end of the medulla containing the central canal's continuation.

Open Part of Medulla

The upper end of the medulla where the central canal becomes visible and connects to the fourth ventricle.

Pyramid of Medulla

The convex structure on the ventral surface of the medulla due to corticospinal fibers.

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Olive in Medulla

A structure laterally located to the pyramid containing the inferior olivary nucleus.

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Cranial Nerves

Nerves that have attachments related to the medulla, especially the last seven.

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Hypoglossal Trigone

The area at the lower corner of the fourth ventricle adjacent to the midline of the medulla.

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Vagal Trigone

Lateral area adjacent to the hypoglossal trigone, associated with vagus nerve functions.

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Gracile Tubercles

Elevations on the dorsal surface of the medulla, associated with sensory pathways.

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Cuneate Tubercles

Less well-defined elevations on the dorsal surface of the medulla, similar to gracile tubercles.

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Vital Centres

Cardiac, respiratory, and vasomotor centers in the reticular formation vital for life.

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Area Postrema

Region in the medulla responsible for vomiting, lacking blood/brain barrier.

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Reticular Formation

Network in the brainstem involved in consciousness and wakefulness.

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Extrapyramidal System

Part of the motor system involved in controlling involuntary movements.

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Circadian Rhythms

Biological processes that display an oscillation of about 24 hours.

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Medullary Blood Supply

The medulla is supplied by the vertebral, basilar, and posterior inferior cerebellar arteries.

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Medial Medullary Syndrome

Condition caused by damage to medial blood vessels leading to paralysis of the tongue and hemiplegia.

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Lateral Medullary Syndrome

Syndrome from lateral blood vessel damage causing dysphagia and vertigo.

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Horner's Syndrome

Condition resulting from sympathetic pathway interruption, causing pupil constriction.

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Spinal Tracts

Pathways carrying sensory and motor information from the spinal cord.

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Decussation of the pyramids

The crossing of motor fibers from one side of the brain to the other in the medulla.

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Hyoglossal nucleus

Nucleus in the medulla that controls tongue movement via the hypoglossal nerve.

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Dorsal nucleus of the vagus

A nucleus containing motor cell bodies for the vagus nerve's autonomic functions.

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Nucleus of the tractus solitarius

A nucleus involved in sensory processing related to taste and visceral functions.

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Inferior olivary nucleus

A C-shaped nucleus in the medulla contributing to motor coordination.

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Cuneate nucleus

Nucleus in the medulla that transmits proprioceptive impulses from the upper body.

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Gracile nucleus

Nucleus that processes sensory data from the lower body in the medulla.

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Nucleus ambiguus

Contains motor neurons for muscles of the larynx, pharynx, and soft palate.

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Study Notes

Medulla Oblongata: Structure and Function

  • Located between the pons and spinal cord, positioned vertically from the occipital bone to the atlas, within the cerebellar vallecula.
  • Divided into an 'open' part (upper end, fourth ventricle floor) and a 'closed' part (lower end, spinal cord canal continuation).
  • Ventral aspect: midline grooves, prominent pyramids (corticospinal fibers), olives (inferior olivary nucleus), and inferior cerebellar peduncles.
  • Cranial nerve attachments: nerves VI, VII (and its intermedius component), VIII, IX, X, and XI rootlets emerge from distinct locations relative to the pons, pyramids, olives and inferior cerebellar peduncles. Nerve XII rootlets arise from areas between the pyramid and olive.
  • Dorsal aspect: lower fourth ventricle floor, gracile and cuneate tubercles, and trigeminal tubercle.

Internal Structure

  • Upper medulla: easily identifiable pyramids and olives.
  • Closed medulla: retains pyramids ventrally, but adds gracile and cuneate tubercles dorsally.
  • Pyramids decussate (cross) in the lower medulla, followed by medial lemniscus fiber decussation slightly higher.
  • Nuclei positioned below fourth ventricle floor: hypoglossal, dorsal vagus, nucleus of tractus solitarius, spinal trigeminal nucleus, vestibular and cochlear nuclei, nucleus ambiguus, and inferior olivary nucleus.

Nuclei and Their Functions

  • Hypoglossal nucleus: controls hypoglossal nerve for tongue movements.
  • Dorsal vagal nucleus: controls cardiac, visceral muscle and gland secretions (primarily stomach). Its sensory role is now attributed to nucleus of tractus solitarius.
  • Nucleus of tractus solitarius: receives taste and visceral sensory fibers (e.g. from carotid sinus, carotid body, aortic arch). Crucial for cough, sneeze, gag, and vomiting reflexes.
  • Nucleus ambiguus: controls skeletal muscles of the larynx, soft palate, pharynx, and upper esophagus (motor).
  • Inferior olivary nucleus: C-shaped lamina; its fibers (olivocerebellar) decussate and enter the inferior cerebellar peduncle.
  • Gracile and cuneate nuclei: receive spinal cord sensory fibers; responsible for medial lemniscus formation. Cuneate cells with accessory cuneate nucleus convey upper limb proprioceptive information to cerebellum.
  • Medullary reticular formation: irregular cell and fiber mass interspersed with other structures. Includes cardiovascular (cardiac, respiratory, vasomotor), cough, sneeze, gag, vomit centers. Vital for alertness and consciousness; major role in controlling motor activity (extrapyramidal), sensory input modulation (thalamus), autonomic function, and circadian rhythms.

Blood Supply and Clinical Syndromes

  • Ventral supply: vertebral and basilar arteries.
  • Lateral and dorsal supply: posterior inferior cerebellar artery.
  • Medial medullary syndrome: damage to vessels supplying the pyramid, medial lemniscus, and hypoglossal nucleus results in tongue paralysis, contralateral hemiplegia, and sensory loss.
  • Lateral medullary syndrome (syndrome of the posterior inferior cerebellar artery): damage produces vocal fold paralysis, dysphagia, facial and body sensory loss, Horner's syndrome, vertigo, nystagmus, and nausea/vomiting,

Additional Structures

  • Area postrema: near gracile nuclei. Contains vomiting center and chemoreceptor trigger zone. Lacks blood-brain barrier.
  • Medullary veins: drain dorsally to occipital sinuses, and ventrally into basilar plexus and inferior petrosal sinuses.

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Description

Explore the intricate structure and functions of the medulla oblongata, located between the pons and the spinal cord. This quiz covers key anatomical features, cranial nerve attachments, and the medulla's internal structure, providing a deep understanding of its role in the nervous system.

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