Medical Nutrition Therapy in Kidney Disease

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Questions and Answers

The kidney filters approximately $1600$ L of blood per day.

True (A)

A patient with a GFR of 55 mL/min/1.73m² would be classified as having Stage 3 chronic kidney disease.

True (A)

A patient with chronic kidney disease can be classified as having Stage 1 even if their GFR is above 100 mL/min/1.73m².

True (A)

The kidney's primary function is to regulate the levels of fluids, electrolytes, and organic solutes in the body, maintaining a stable internal environment.

<p>True (A)</p> Signup and view all the answers

Patients with kidney failure will always have a GFR below 15 mL/min/1.73m².

<p>False (B)</p> Signup and view all the answers

The glomerulus is responsible for filtering blood and preventing the passage of blood cells and protein.

<p>True (A)</p> Signup and view all the answers

Continuous Ambulatory Peritoneal Dialysis (CAPD) typically involves 2-3 hour exchange cycles throughout the day.

<p>False (B)</p> Signup and view all the answers

The kidney's ability to eliminate nitrogenous waste products is referred to as renal failure.

<p>False (B)</p> Signup and view all the answers

Hemodyalisis patients typically receive treatment 2-3 times per week, for a duration of 2-3 hours each session.

<p>False (B)</p> Signup and view all the answers

The kidneys regulate blood pressure through the production of erythropoietin, a hormone involved in red blood cell production.

<p>False (B)</p> Signup and view all the answers

Acute Renal Failure (ARF) is marked by a sudden decrease in the glomerular filtration rate (GFR).

<p>True (A)</p> Signup and view all the answers

Increasing carbohydrate intake to above 150g daily reduces protein breakdown by more than 50%.

<p>False (B)</p> Signup and view all the answers

The recommended protein intake for non-dialysis patients with chronic kidney disease is between 0.8 and 1.2 g/kg.

<p>True (A)</p> Signup and view all the answers

In the early stages of ARF, patients can often eat normally and do not require nutritional support.

<p>False (B)</p> Signup and view all the answers

Chronic Kidney Disease (CKD) is classified into five stages based on the severity of the condition.

<p>True (A)</p> Signup and view all the answers

The estimated daily calorie needs for a patient with chronic kidney disease are approximately 40-50 kcal/kg.

<p>False (B)</p> Signup and view all the answers

Individuals on hemodialysis should restrict their daily potassium intake to between 2 and 3 grams.

<p>True (A)</p> Signup and view all the answers

A patient on hemodialysis with hypertension and edema may need to restrict their fluid intake.

<p>True (A)</p> Signup and view all the answers

A patient on hemodialysis should strive for a weight gain of 2 to 3 kg between dialysis sessions.

<p>True (A)</p> Signup and view all the answers

The recommended daily sodium intake for most patients on hemodialysis is 2-3 grams.

<p>True (A)</p> Signup and view all the answers

The energy requirement for an adult on hemodialysis is 15-20 kcal/kg of ideal body weight.

<p>False (B)</p> Signup and view all the answers

The amount of protein required daily for an adult on hemodialysis is 0.8 g/kg of ideal body weight.

<p>False (B)</p> Signup and view all the answers

A patient on hemodialysis who experiences a 65% or greater reduction in serum urea is considered poorly dialyzed.

<p>False (B)</p> Signup and view all the answers

Renal osteodystrophy is a common complication of ESRD that can affect calcium, phosphorus, and vitamin D levels.

<p>True (A)</p> Signup and view all the answers

A serum ferritin level below 100 ng/dL is a hallmark of absolute iron deficiency in patients with Chronic Kidney Disease (CKD).

<p>True (A)</p> Signup and view all the answers

A patient on dialysis should limit their intake of dairy products to 2 servings per day.

<p>False (B)</p> Signup and view all the answers

The recommended target hemoglobin (Hb) level for patients with CKD is between 10.0 and 11.0 g/dL.

<p>False (B)</p> Signup and view all the answers

Folic acid deficiency can cause macrocytic anemia and is often exacerbated by hemodialysis due to the loss of folic acid in the dialysate.

<p>True (A)</p> Signup and view all the answers

A TSAT greater than 20% and a serum ferritin level above 200 ng/dL are recommended targets for iron supplementation in hemodialysis patients to ensure adequate iron stores for erythropoiesis.

<p>True (A)</p> Signup and view all the answers

The recommended daily intake of fruits, vegetables, and juices for dialysis patients is restricted to eight servings.

<p>False (B)</p> Signup and view all the answers

Epoetin and Darbepoetin are erythropoiesis-stimulating agents that have significantly improved the treatment of anemia in dialysis and CKD patients.

<p>True (A)</p> Signup and view all the answers

A patient on dialysis should limit their fluid intake to prevent a weight gain exceeding 3.0 kg between treatments.

<p>False (B)</p> Signup and view all the answers

As the GFR decreases, phosphorus is retained in the plasma due to its renal excretion being enhanced.

<p>False (B)</p> Signup and view all the answers

Patients with ESRD commonly experience glucose intolerance with hyperglycemia but not hypoglycemia.

<p>False (B)</p> Signup and view all the answers

Anemia is less prevalent in stage 4 CKD compared to earlier stages.

<p>False (B)</p> Signup and view all the answers

The World Health Organization defines anemia as a Hb level of less than 14 g/dL for men.

<p>False (B)</p> Signup and view all the answers

Erythropoietin is insufficiently produced due to factors including the bone marrow's decreased response to oxygen delivery.

<p>True (A)</p> Signup and view all the answers

Calcium intake is generally kept low in order to mitigate the impacts of hyperparathyroidism in renal failure.

<p>False (B)</p> Signup and view all the answers

Iron deficiency is the least significant contributor to anemia in chronic kidney disease compared to other factors.

<p>False (B)</p> Signup and view all the answers

Levels of fat-soluble vitamins typically show greater fluctuations than water-soluble vitamins in patients with renal disease.

<p>False (B)</p> Signup and view all the answers

Flashcards

Fluid and Sodium Balance in ESRD

The kidney's inability to regulate sodium and water in ESRD patients can lead to hypertension and edema.

Sodium Restriction in ESRD

Dialysis patients with hypertension and edema may need to restrict their sodium and fluid intake.

Potassium Management in ESRD

Potassium levels should be closely monitored and intake may need to be restricted in ESRD patients.

Protein Needs in ESRD

Dialysis patients require increased protein intake to compensate for protein loss during dialysis.

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High-Quality Protein in ESRD

High-quality protein intake is crucial for ESRD patients to ensure sufficient protein synthesis.

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Energy Needs in ESRD

Energy intake must be adequate to prevent protein breakdown for energy production.

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Metabolic Bone Disease in ESRD

A major complication of ESRD is metabolic bone disease, or renal osteodystrophy.

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Calcium, Phosphorus & Vitamin D in ESRD

Calcium, phosphorus and vitamin D play a vital role in bone health and require special management in ESRD.

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Stage 1 CKD

Kidney function is normal or slightly increased, but there is evidence of kidney damage.

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Stage 2 CKD

Kidney function is mildly decreased, but there is evidence of kidney damage.

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Stage 3 CKD

Kidney function is moderately decreased, there is significant evidence of kidney damage.

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Stage 4 CKD

Kidney function is severely decreased, kidney failure is approaching.

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Stage 5 CKD

Kidney function is very low, you need dialysis or transplant.

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Hemodialysis

A process where waste products and excess fluid are removed from the blood using a machine.

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Peritoneal Dialysis

A process where waste products and excess fluid are removed from the blood using the peritoneum, a membrane lining the abdomen.

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Nutritional Therapy in CKD

The goal is to achieve optimal nutritional status by controlling protein, calorie, fluid intake.

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Phosphorus Retention in Renal Failure

A condition in which the kidneys are not filtering waste products effectively, leading to a buildup of phosphorus in the blood.

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Hypocalcemia in Renal Failure

Lower than normal calcium levels in the blood, often seen in patients with kidney failure.

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Hyperparathyroidism in Renal Failure

Excessive activity of the parathyroid glands, leading to increased levels of parathyroid hormone (PTH) in the blood.

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Anemia in Chronic Kidney Disease

Anemia is a common complication of chronic kidney disease (CKD) and end-stage renal disease (ESRD).

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Erythropoietin

A hormone produced by the kidneys that stimulates the production of red blood cells in the bone marrow.

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Iron Deficiency in CKD

A significant contributing factor to anemia in patients with CKD, usually due to a lack of iron available for red blood cell production.

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Hyperglycemia in ESRD

A condition characterized by high blood sugar levels, often seen in patients with ESRD.

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Hypoglycemia in ESRD

A condition characterized by low blood sugar levels, often seen in patients with ESRD.

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What is the main function of the kidneys?

The main function of the kidneys is to maintain a balance of fluids, electrolytes, and organic solutes in the body.

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What are nephrons and how many are in each kidney?

Each kidney contains approximately 1 million nephrons, the functional units responsible for filtering waste and regulating blood pressure.

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What is the glomerulus and what is its function?

The glomerulus is the filtration unit of the nephron, responsible for removing waste products from the blood.

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What is the role of the tubules in the nephrons?

The tubules of the nephrons are responsible for reabsorbing essential nutrients and water back into the bloodstream.

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How do kidneys contribute to water balance in the body?

The kidney plays a critical role in maintaining water balance by regulating the amount of water excreted in urine.

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What is Acute Renal Failure (ARF)?

Acute Renal Failure (ARF) is a sudden decrease in the kidney's ability to filter waste products, often leading to a buildup of toxins in the blood.

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What is Chronic Kidney Disease (CKD)?

Chronic Kidney Disease (CKD) is a progressive decline in kidney function over time, often requiring dialysis or transplantation.

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What is Total Parenteral Nutrition (TPN)?

Total Parenteral Nutrition (TPN) is a method of providing nutrition directly into the bloodstream, bypassing the digestive system.

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Absolute Iron Deficiency

A state where circulating iron and the body's total iron stores are depleted.

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Folic Acid or Vitamin B12 Deficiency

Low levels of either folic acid or vitamin B12 can lead to the development of macrocytic anemia.

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Anemia of Chronic Kidney Disease (CKD)

Anemia caused by kidney failure, where the kidneys are unable to produce enough erythropoietin.

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Erythropoietin (EPO)

A hormone produced by the kidneys that stimulates the production of red blood cells.

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Transferrin Saturation (TSAT)

A blood test measuring the percentage of transferrin in the blood that is saturated with iron.

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Serum Ferritin

A blood test measuring the amount of iron stored in the body.

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Erythropoiesis-Stimulating Agents (ESAs)

A common treatment for anemia in CKD patients, stimulating red blood cell production.

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Iron Therapy for Dialysis Patients

The goal of iron therapy in dialysis patients is to maintain TSAT greater than 20% and serum ferritin above 200 ng/dL to support red blood cell production.

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Study Notes

Medical Nutrition Therapy in Kidney Disease

  • Medical nutrition therapy is crucial in managing kidney diseases, including acute renal failure (ARF) and chronic kidney disease (CKD).
  • The kidney’s primary functions are excretory, endocrine, and metabolic.
  • Kidney function can be affected by conditions such as ARF and CKD, leading to potential nutritional imbalances.

Kidney Anatomy

  • The kidneys receive 20% of cardiac output.
  • This allows for the filtering of roughly 1600 liters a day of blood.
  • Only 1.5 liters of urine are excreted daily.
  • Each kidney contains one million nephrons.
  • Nephrons consist of a glomerulus, loop of Henle, distal tubule, and collecting duct.
  • The glomerulus filters blood, excluding blood cells and protein.
  • Tubules reabsorb most components in the ultrafiltrate.
  • The kidney regulates water homeostasis.
  • Main waste products are urea, uric acid, creatinine, and ammonia.
  • The kidney's ability to eliminate waste is renal function.

Acute Renal Failure (ARF)

  • Characterized by a sudden reduction in glomerular filtration rate (GFR).
  • Nutritional care is vital, as patients often experience uremia, metabolic acidosis, and physiological stress.
  • Total parenteral nutrition (TPN) and early dialysis are often used in early stages.
  • TPN and early dialysis can positively affect patient survival.

Chronic Kidney Disease (CKD)

  • CKD has five stages, categorized by GFR levels.
  • CKD stages are divided based on the GFR.
  • The GFR measurements classify various levels of CKD.

Nutritional Goals for ESRD (End-Stage Renal Disease) patients on Hemodialysis

  • Prevent deficiencies and maintain good nutritional status.
  • Adequacy of protein, energy, vitamins, and minerals is vital.
  • Control edema and electrolyte imbalances by regulating sodium, potassium, and fluid intake.
  • Prevent or delay renal osteodystrophy by managing calcium and vitamin D intake.
  • Enable patients to eat palatable and attractive diets appropriate to their lifestyle.

Nutritional Requirements for Dialysis Patients

  • Energy needs: 30-40 kcal/kg of ideal body weight.
  • Carbohydrate intake (100g over 24 hours) reduces protein breakdown by 50%.
  • Protein intake: Non-dialysis - 0.5-0.8 g/kg; Dialysis -1-2 g/kg ideal body weight. A significant portion should be high biological value protein.
  • Fluid intake is often restricted to avoid weight gain.

Fluid and Sodium Balance

  • The kidney's ability to handle sodium and water needs to be frequently assessed.
  • Assessing aspects include blood pressure, edema presence, sodium dietary intake, and serum sodium levels,
  • Sodium Intake (g/day): 2-3.
  • Dialysis patients with hypertension and edema may need restricted sodium and fluid intake.
  • Patients should be guided to manage thirst without excessive fluid intake.
  • Weight gain from fluid should be limited to 2-3 kg.

Potassium

  • Potassium restriction is often necessary, depending on factors such as individual body size, serum potassium levels, urine output, and dialysis frequency.
  • Daily intake ranges from 3-5 grams, and is usually reduced to 2-3 grams in ESRD on dialysis.

Vitamin Supplements

  • Water-soluble vitamins are often lost during dialysis; levels of fat-soluble vitamins remain relatively stable.
  • Vitamin K supplements should generally be avoided, given patient use of anticoagulants.

Anemia in CKD

  • Anemia in CKD and ESRD patients is a frequent complication.
  • Causes include erythropoietin deficiency, iron deficiency, folate and vitamin B12 deficiency.
  • Anemia can be assessed via HB levels.
  • Recommended HB levels are 11.0–12.0 g/dL generally.

Calcium, Phosphorus, and Vitamin D

  • Metabolic bone disease (renal osteodystrophy) is a significant complication in ESRD.
  • Serum phosphorus levels increase as glomerular filtration rate (GFR) declines.
  • To avoid complications, calcium and phosphorus intake are individually controlled with diets.

Dietary Considerations

  • Typical food options include limiting dairy intake to one serving daily, and limiting fruits, vegetable, and juices to six servings per day.
  • Examples of food to limit include milk, nondairy creamer, alternatives, eggs, toast, muffins, bagels, fruit, snacks (sandwiches, cookies, crackers), certain beverages, and cold or hot cereal.

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