Medical Microbiology Lesson 17: Innate and Acquired Immunity

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31 Questions

Which type of immunity is characterized by non-specific protection and does not require prior exposure to a pathogen?

Innate immunity

Which of the following is not a non-specific protective factor of the organism?

Antibodies

What is the process by which phagocytes engulf and digest foreign particles such as bacteria?

Phagocytosis

Which factor enhances the ability of phagocytes to recognize and engulf pathogens?

Opsonization

Which mechanism of killing microorganisms in phagocytes is oxygen-dependent?

Respiratory burst

What is the term for the process by which phagocytes present antigens to T cells to initiate an immune response?

Antigen processing

Which type of immunity is insensitive to antigens and is passed on to the next generation?

Innate immunity

What type of immunity is formed after exposure to microorganisms or other antigens and is not transmitted from generation to generation?

Acquired immunity

Which type of acquired immunity is natural rather than artificial?

Active immunity

What type of immunity is not transmitted from generation to generation and can be either natural or artificial?

Acquired immunity

Which type of immunity is characterized by the complete elimination of pathogens from the body?

Sterile immunity

In which type of immunity does the activity of specific defense factors depend on the type of antigens that enter the body?

Specific immunity

What are the outer barriers of the organism for non-specific defense factors?

Skin and mucous membranes

What is the primary function of non-specialized defense factors in the immune system?

To activate other immune factors

What do specialized defense factors primarily function as in the immune system?

To defend the organism

What is the chemical composition of antibiotics?

Proteins and nucleic acids

What is the mechanism of resistance to antibiotics in microorganisms?

Reduced antibiotic target binding

What is the effect spectrum of broad-spectrum antibiotics?

Effective against a wide range of microorganisms

How are antibiotic susceptibility of bacteria determined by the dilution method?

By analyzing the growth in varying concentrations of antibiotics

What are the sources of antibiotics?

Bacteria, animals, and plants

Which type of immunity is characterized by non-specific protection and does not require prior exposure to a pathogen?

Innate immunity

What is the main purpose of chemical therapeutic drugs in the treatment of infectious diseases?

Acting on etiological pathogens without impacting body tissues

Who is credited as the founder of chemotherapy and proposed the 'magic bullet' idea?

Paul Ehrlich

What is the main principle behind P. Ehrlich's 'magic bullet' idea in chemical therapy?

Killing microbes without impacting body tissues

What is the chemical therapeutic index used for in the evaluation of therapeutic drugs?

To assess the ratio of minimal therapeutic dose killing pathogen to the highest dose which organism can resist

What distinguishes narrow spectrum drugs from broad spectrum drugs based on their activity spectrum?

Narrow spectrum drugs act on a limited number of species, while broad spectrum drugs act on both gram negative and gram positive bacteria species

What is the primary difference between microbocide and microbostatic drugs based on their action type?

Microbocide drugs kill bacteria, while microbostatic drugs inhibit microbial growth

How are antimicrobial drugs classified based on their source?

Based on their method of obtaining (synthetic or natural origin)

Which main groups of chemotherapeutic drugs are obtained by chemical synthesis?

'Synthetic' chemotherapeutic drugs

What determines the activity spectrum of therapeutic drugs?

The groups of microorganisms on which they have effect

What does chemical therapy aim to treat?

Pathogens causing infectious diseases without impact on body tissues

Test your knowledge on the concepts, types, and forms of immunity, including innate and acquired immunity, non-specific protective factors of the organism, and phagocytosis. This quiz covers the features and factors of innate (non-specific) immunity, as well as the determination of phagocytic activity of leukocytes.

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