Medical Important Viruses Overview
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Questions and Answers

Which virus is classified under the genus hepevirus?

  • Rotavirus
  • Hepatitis E virus (correct)
  • Hepatitis C virus
  • Norwalk virus
  • What type of genetic material do reoviruses possess?

  • Circular DNA
  • Positive-polarity RNA
  • Double-stranded linear RNA (correct)
  • Single-stranded RNA
  • Which virus is NOT part of the flavivirus group?

  • Rubella virus (correct)
  • Dengue virus
  • Hepatitis C virus
  • Yellow fever virus
  • What characteristic defines retroviruses?

    <p>Diploid single-stranded RNA and reverse transcription</p> Signup and view all the answers

    Which groups of viruses are classified as paramyxoviruses?

    <p>Helical nucleocapsid viruses with negative-polarity RNA</p> Signup and view all the answers

    Which of the following is the main human pathogen associated with orthomyxoviruses?

    <p>Influenza virus</p> Signup and view all the answers

    Which of the following viruses is a member of the lentivirus group?

    <p>Human immunodeficiency virus (HIV)</p> Signup and view all the answers

    What is the primary structure of togaviruses?

    <p>Single-stranded, linear, nonsegmented, positive-polarity RNA</p> Signup and view all the answers

    What type of genetic material do adenoviruses contain?

    <p>Double-stranded linear DNA</p> Signup and view all the answers

    What is a key characteristic of hepadnaviruses?

    <p>They are enveloped with a unique double-stranded circular DNA.</p> Signup and view all the answers

    Which of the following is NOT a herpesvirus associated with human disease?

    <p>Coxsackievirus</p> Signup and view all the answers

    What is the shape of poxviruses?

    <p>Bricklike</p> Signup and view all the answers

    Which family of viruses is the smallest?

    <p>Picornaviruses</p> Signup and view all the answers

    What type of virus are caliciviruses categorized as?

    <p>Naked icosahedral virus</p> Signup and view all the answers

    What main infection is primarily caused by herpes simplex virus type 1?

    <p>Cold sores</p> Signup and view all the answers

    Which viral family has members that can cause respiratory diseases?

    <p>Adenoviruses</p> Signup and view all the answers

    What term is used to describe a virus that lacks a lipid-containing membrane surrounding its nucleocapsid?

    <p>Naked virus</p> Signup and view all the answers

    Which of the following steps is NOT part of the viral replication cycle?

    <p>Protein synthesis</p> Signup and view all the answers

    What characterizes enveloped viruses in relation to their structure?

    <p>Their nucleocapsid is flexible and coiled within the envelope.</p> Signup and view all the answers

    Which group of viruses is classified as dsRNA?

    <p>Reoviruses</p> Signup and view all the answers

    What do the proteins found in the envelope of an enveloped virus originate from?

    <p>Host cell membranes</p> Signup and view all the answers

    Which statement about papovaviruses is accurate?

    <p>They are composed of double-stranded circular supercoiled DNA.</p> Signup and view all the answers

    Which of the following viruses is NOT a member of the hepadnavirus family?

    <p>JC virus</p> Signup and view all the answers

    In terms of size, which of the following virus families is known to be the largest?

    <p>Poxviruses</p> Signup and view all the answers

    What is the primary mode of transmission of MERS to humans?

    <p>Close contact with camels</p> Signup and view all the answers

    What is the virus strain responsible for COVID-19?

    <p>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)</p> Signup and view all the answers

    Which of the following symptoms is NOT commonly associated with COVID-19?

    <p>Skin rash</p> Signup and view all the answers

    What percentage of people who become infected with COVID-19 typically recover without special treatment?

    <p>80%</p> Signup and view all the answers

    During the 2019–20 pandemic, when was COVID-19 declared a pandemic by WHO?

    <p>March 11, 2020</p> Signup and view all the answers

    What are the common mild symptoms that can begin gradually in COVID-19 patients?

    <p>Aches, dry cough, and nasal congestion</p> Signup and view all the answers

    Which group of individuals is more likely to develop serious illness from COVID-19?

    <p>Older adults and those with underlying health conditions</p> Signup and view all the answers

    What is the incubation period for COVID-19 as stated in the content?

    <p>1-14 days</p> Signup and view all the answers

    What properties contribute to the classification of a virus into genera and species?

    <p>Host range and amino acid sequences of viral proteins</p> Signup and view all the answers

    What type of viral genome is capable of serving directly as a template for protein synthesis?

    <p>Positive polarity RNA</p> Signup and view all the answers

    Which of the following describes a characteristic of capsids with helical symmetry?

    <p>They are rod-shaped or coiled structures.</p> Signup and view all the answers

    How are capsomers related to icosahedral symmetry in viral capsids?

    <p>They are the building blocks of structural subassemblies in icosahedral capsids.</p> Signup and view all the answers

    What is a key difference between positive-strand and negative-strand RNA viruses?

    <p>Positive-strand can immediately translate to proteins; negative-strand cannot.</p> Signup and view all the answers

    What type of symmetry do most viral capsids exhibit, according to their geometric configurations?

    <p>Most demonstrate helical or icosahedral symmetry.</p> Signup and view all the answers

    What defines the nucleocapsid of a virus?

    <p>The complex of polypeptides and viral nucleic acid</p> Signup and view all the answers

    What is the role of hydrogen bonding in the structure of viral capsids?

    <p>To stabilize the polypeptide units in capsids</p> Signup and view all the answers

    Which type of vaccine uses mRNA technology?

    <p>Pfizer-BioNTech vaccine</p> Signup and view all the answers

    What type of virus is characterized by having an envelope?

    <p>Hepadnaviruses</p> Signup and view all the answers

    Which of the following vaccines is classified as a viral vector vaccine?

    <p>Oxford AstraZeneca vaccine</p> Signup and view all the answers

    What type of RNA virus is characterized by having double-stranded RNA?

    <p>Reoviruses</p> Signup and view all the answers

    Which of the following vaccines requires only one dose?

    <p>Johnson &amp; Johnson vaccine</p> Signup and view all the answers

    Which RNA viruses have positive-polarity RNA?

    <p>Picornaviruses and coronaviruses</p> Signup and view all the answers

    Which of the following is NOT classified as a DNA virus family?

    <p>Caliciviruses</p> Signup and view all the answers

    What is the primary method for classifying viruses?

    <p>Nature of the genome</p> Signup and view all the answers

    Study Notes

    Medical Important Viruses

    • Viruses are infectious agents composed of a genome (RNA or DNA, not both) and a protein capsid.
    • Some viruses have an additional lipid envelope.
    • A complete virus particle is called a virion.
    • Viruses replicate inside host cells.
    • Viral replication is a complex process, often obligately intracellular.
    • Viral pathogenicity depends on various structural and functional characteristics.
    • Different virus species can have distinct clinical pathologies.
    • Viruses are significantly smaller than host cells (100-1000x).
    • Size ranges from 20nm to 300nm in diameter.
    • Viruses used for classifying families, genera, and species.
    • Classification factors:
      • Type and structure of viral nucleic acid.
      • Viral replication strategy.
      • Viral capsid symmetry (helical or icosahedral).
      • Presence or absence of a lipid envelope.

    Viral Structure

    • Viruses have a protein coat (capsid) that protects the nucleic acid.
    • Icosahedral symmetry is common with capsid composed of multiple copies of a single polypeptide(s).
    • Helical symmetry is another capsid structure. Its formed from repeating units of a polypeptide that aggregate.
    • Some viruses have an envelope (membrane) composed of a lipid bilayer that surrounds the capsid.

    Viral Replication

    • Viral replication involves several steps, including attachment, penetration, uncoating, genome replication, protein synthesis, assembly, and release of new virions.

    Virus Classification

    • Baltimore classification categorizes viruses into seven groups based on their genome structure and replication strategy.
      • I: dsDNA viruses, II: ssDNA viruses, III: dsRNA viruses, IV: (+)ssRNA viruses, V: (−)ssRNA viruses, VI: ssRNA-RT viruses, and VII: dsDNA-RT viruses.
    • Based on structure, some are naked, i.e., nonenveloped and others are enveloped.
    • Some important naked and enveloped virus families: - Parvoviruses (Naked) - Adenoviruses (Naked) - Papovaviruses (Naked) - Poxviruses (Enveloped) - Herpesviruses (Enveloped) - Hepadnaviruses (Enveloped)

    Viral Diseases

    • Various viruses cause diseases in humans.
      • Example of the viruses involved in causing diseases and outbreaks: - COVID-19, - SARS, - MERS, - Measles, - influenza, - HIV.

    Viral Detection Methods

    • Molecular tests, such as PCR, detect viral nucleic acid.
    • Serological tests detect antibodies indicative of prior infection.

    Viral prevention and treatment

    • Vaccination and other preventive strategies can provide immunity to specific viral infections.
    • antiviral drugs.

    Viral classification and nomenclature:

    • Viruses are classified into families, genera, and species based on relatedness, similarities, and distinguishing characteristics.
    • Viruses different from bacteria: The virus classification uses different nomenclature compared to bacteria for their distinct characteristics.

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    Medical Important Viruses PDF

    Description

    This quiz covers essential information about medical viruses, including their structure, replication, and classification. Explore the characteristics that distinguish various virus species and learn about the role of virions in pathogenicity. Test your understanding of viral structure and function.

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