Colloquium 2015-1(88-110)
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Questions and Answers

A 57-year-old woman presents to the emergency department with right leg numbness, tingling, and weakness 1 week after coronary angiography. On examination, there is a pulsatile nontender mass in the right groin (the side of the arterial puncture). The mass is getting bigger each day. What is this patient's most likely diagnosis?

  • Expanding pseudoaneurysm (correct)
  • Arteriovenous fistula
  • Femoral nerve injury after angiography
  • Infected pseudoaneurysm
  • Acute arterial occlusion

A 57-year-old woman with morbid obesity is incidentally noted to have mildly elevated AST (SGOT) levels. She does not take any medications nor any alcohol and a workup for viral hepatitis and hemochromatosis is negative. Which one of the following is most likely to improve her hepatic condition?

  • Simvastatin
  • Clopidogrel
  • Vitamin E
  • Weight loss (correct)
  • L-carnitine

You suspect that he has asthma in a 15-year-old healthy male with nighttime cough and wheezing for the past several months. Which one of the following would be most appropriate at this point?

  • Treat empirically with a short-acting beta-agonist
  • Order a chest X Ray
  • Perform spirometry (correct)
  • Start an inhaled corticosteroid
  • Start a leukotriene inhibitor

Which one of the following is the best treatment for a 36-year-old female presents with a several-week history of polyuria and intense thirst, a urinalysis with low specific gravity and low osmolality and a 24-hour urine output more than 5 liters. All other lab and exam findings are normal.

<p>vasopressin (D)</p> Signup and view all the answers

Routine vaccination against which one of the following organisms has significantly reduced the risk of bacterial meningitis among young children?

<p>Haemophilus influenzae (B)</p> Signup and view all the answers

To prevent joint damage from gout, uric acid levels should be lowered by medication to

<p>&lt;6.0mg/dL (A)</p> Signup and view all the answers

A 50-year-old male presents with gynecomastia. Which one of the following antihypertensive medications is most likely to cause this problem?

<p>Spironolactone (D)</p> Signup and view all the answers

Which one of the following intravenous agents is the best INITIAL management for hypercalcemic crisis?

<p>Saline (B)</p> Signup and view all the answers

A postmenopausal female presents with a recent onset of painless vaginal bleeding. Her pelvic examination is normal and all previous PAP smears were normal. Which one of the following management options is the preferred next diagnostic step?

<p>Transvaginal ultrasonography (C)</p> Signup and view all the answers

Which one of the following is true about acute COPD exacerbation?

<p>Systemic corticosteroid therapy reduces the hospital length of stay in patients (D)</p> Signup and view all the answers

A 75-year-old woman is admitted because of mild heart failure. She is acutely symptomatic with dyspnea. Her heart rate is 96 beats/min, blood pressure of 140/90 mm Hg, and an oxygen saturation of 94% on room air. A chest radiograph shows mild pulmonary congestion. What is your recommendation regarding placement of an indwelling urinary catheter for accurate measurement of urine output and for patient comfort?

<p>Placement of an indwelling urinary catheter only until initial diuresis is completed (A)</p> Signup and view all the answers

A 75-year-old male with a history of hypertension has a TIA episode resolved spontaneously within 20 minutes. Carotid Doppler ultrasonography and cerebral angiography both reveal significant carotid stenosis. In addition to starting aspirin, which one of the following would be the most appropriate next step for this patient?

<p>High-dose statin therapy (A)</p> Signup and view all the answers

Which one of the following is the most accurate imaging study for assessing early osteomyelitis?

<p>MRI (B)</p> Signup and view all the answers

Which one of the following should be ordered to evaluate the patient for hereditary hemochromatosis?

<p>A serum iron panel, including a serum ferritin level and transferrin saturation (A)</p> Signup and view all the answers

Which one of the following is recommended for the initial management of a 4 year old male child with ADHD?

<p>Behavioral treatment alone (E)</p> Signup and view all the answers

Azithromycin should be used with caution in a 65-year-old male with coronary artery disease due to an increased risk for

<p>fatal arrhythmias (B)</p> Signup and view all the answers

Which one of the following intranasal medications is considered optimal treatment for a young man with known seasonal allergic rhinitis every autumn who presents to you in September with runny nose.

<p>Glucocorticoids (D)</p> Signup and view all the answers

A 30 year old construction worker fell down on his anterolateral leg from a 3 meter high scaffold 5 hours prior to presentation to emergency. On exam the anterolateral lower leg is quite tender but only slightly swollen, and there is exquisite pain in that area with passive plantar flexion of the great toe. X-Rays and rest of the exam are negative. Which one of the following would be most appropriate?

<p>Urgent orthopedic referral for possible fasciotomy (B)</p> Signup and view all the answers

Which one of the following diseases is associated with Erythema Nodosum?

<p>Crohn's disease (D)</p> Signup and view all the answers

Postmenopausal hormonal therapy with estrogen and progesterone results in a decrease in which one of the following

<p>Hip fracture (B)</p> Signup and view all the answers

TSH receptor site antibodies would indicate which one of the following as the cause of thyroid gland enlargement?

<p>Graves disease (B)</p> Signup and view all the answers

You suspect a patient to be low risk for deep vein thrombosis, which test is preferred to rule it out?

<p>D-dimer assessment (D)</p> Signup and view all the answers

A 4-month-old female is brought to your office by her parents for a 3-day history of fever up to 38.7°C. She is fussy and her oral intake is down. She has no rash, no emesis, and no diarrhea. Her urine output is normal. On examination she is alert but fussy. Her rectal temperature is 38.4°C. The examination is otherwise normal and there are no focal findings of infection. The parents are reliable and you choose to manage the baby as an outpatient. Which one of the following tests is likely to be most helpful in this situation?

<p>A urinalysis and urine culture (C)</p> Signup and view all the answers

Flashcards

Expanding pseudoaneurysm

An expanding pseudoaneurysm is a localized outpouching of an artery wall caused by trauma or injury, often seen after invasive procedures. It can grow in size and can potentially rupture, leading to serious complications.

Arteriovenous fistula (AVF)

Arteriovenous fistula (AVF) is an abnormal connection between an artery and a vein. It results in increased blood flow into the venous system leading to a palpable thrill and audible bruit.

Acute arterial occlusion

Acute arterial occlusion is a sudden blockage of a blood vessel, leading to a loss of blood supply to tissues. It often presents with pain, numbness, tingling, and coldness in the affected area.

Femoral nerve injury

Femoral nerve injury can occur during procedures involving the femoral artery or surrounding tissues. This injury can result in weakness, numbness, or tingling in the thigh and leg.

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Infected pseudoaneurysm

An infected pseudoaneurysm occurs when a pseudoaneurysm becomes infected. This can be a serious complication, potentially leading to sepsis and other systemic problems.

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Weight loss

Weight loss is an essential component of managing fatty liver disease. It reduces the accumulation of fat in the liver, improving liver function and reducing the risk of complications.

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Simvastatin

Simvastatin is a statin medication that lowers cholesterol levels. While it can indirectly improve some metabolic markers associated with fatty liver, it does not directly address the primary cause.

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L-carnitine

L-carnitine is a naturally occurring compound that plays a role in energy metabolism. It has been studied for potential benefit in fatty liver, but evidence is limited.

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Vitamin E

Vitamin E is an antioxidant that has been studied for its potential benefits in various conditions, including fatty liver. However, its effectiveness in treating fatty liver disease is not well-established.

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Clopidogrel

Clopidogrel is a platelet aggregation inhibitor used to prevent blood clots. It is not directly relevant to the treatment of fatty liver disease.

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Spirometry

The most appropriate first step in evaluating a child with suspected asthma is to perform spirometry. It measures lung function and can help confirm the diagnosis.

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Short-acting beta-agonist

Treating empirically with a short-acting beta-agonist is not the most appropriate first step in a suspected new asthma case. While it can provide temporary relief, it may mask the underlying condition.

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Chest X-ray

A chest X-ray is not typically the first step in evaluating suspected asthma. It is more helpful in excluding other conditions, such as pneumonia.

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Inhaled corticosteroid

Starting an inhaled corticosteroid may be appropriate for persistent asthma, but not the most appropriate initial step for a newly suspected case.

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Leukotriene inhibitor

Starting a leukotriene inhibitor is not the most appropriate initial step in a suspected new asthma case. Leukotriene inhibitors are typically used as maintenance therapy for persistent asthma.

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Vasopressin

Vasopressin (antidiuretic hormone) is the most appropriate treatment for diabetes insipidus. It helps regulate water balance and reduces excessive urine production.

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Angiotensin II

Angiotensin II is a powerful vasoconstrictor and is not the appropriate treatment for diabetes insipidus. It is involved in blood pressure regulation.

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Aldosterone

Aldosterone, a hormone involved in sodium and potassium balance, is not the appropriate treatment for diabetes insipidus.

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Renin

Renin, an enzyme involved in blood pressure regulation, is not the appropriate treatment for diabetes insipidus.

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Insulin

Insulin is a hormone involved in glucose regulation and is not the appropriate treatment for diabetes insipidus.

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Haemophilus influenzae

Routine vaccination against Haemophilus influenzae has significantly reduced the risk of bacterial meningitis among young children. This is because Haemophilus influenzae type b (Hib) was a common cause of bacterial meningitis before the introduction of the Hib vaccine.

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Study Notes

General Medical Information

  • Various medical scenarios are presented, including patients with symptoms like numbness, tingling, weakness in the leg, elevated AST levels, and others.
  • The provided text discusses potential diagnoses, treatments, and diagnostic tests.
  • Information includes age, sex, symptoms, and results of medical examinations or investigations.
  • The notes are specific to the medical cases described.
  • The questions pertain to appropriate next steps in diagnosis and treatment.

Specific Medical Conditions

  • Acute Coronary Angiography: A patient is being evaluated for a complication of acute coronary angiography, specifically an expanding pseudoaneurysm.

  • Morbid Obesity and Liver Function: A patient with morbid obesity presents with elevated AST (SGOT) levels. Weight loss is suggested as an intervention to improve liver condition.

  • Asthma in a 15-Year-Old: A possible asthma exacerbation is suspected in a 15-year-old. Appropriate next steps like spirometry, chest X-ray, or inhaled corticosteroid or leukotriene inhibitor therapy are discussed.

  • Polyuria and Intense Thirst in 36-Year-Old Female: A 36-year-old woman with polyuria, intense thirst, low urine specific gravity, and low osmolality, and urinary output exceeding 5 liters. Vasopressin is suggested as a possible treatment.

  • Bacterial Meningitis: Routine vaccination has significantly reduced risks of bacterial meningitis in young children. Factors like Haemophilus influenzae, Escherichia coli, Borrelia burgdorferi etc are considered during diagnosis.

  • Gout and Joint Damage: Uric acid levels need to be lowered to prevent joint damage from gout. Specific medication levels are mentioned.

  • Gynecomastia in a 50-Year-Old Male: The question pertains to a 50-year-old male patient with gynecomastia. Doxazosin is identified as a possible medication causing this.

  • Hypercalcemic Crisis: Intravenous pamidronate is suggested as an initial treatment for the crisis.

  • Acute COPD Exacerbation: Systemic corticosteroid therapy is briefly discussed.

  • Heart Failure: A 75-year-old patient admitted with mild heart failure presents with dyspnea and low oxygen saturation. Appropriate next step to manage the patient involves the consideration of indwelling urinary catheters for accurate urine output measurements.

  • Transient Ischemic Attack (TIA): A 75-year-old hypertensive male had a spontaneous TIA within 20 minutes. Carotid stenosis and the use of Clopidogrel are relevant to the case.

  • Osteomyelitis: Different imaging studies are discussed as methods to evaluate osteomyelitis.

  • Hereditary Hemochromatosis: A screening for hereditary hemochromatosis involves serum iron panel, including serum ferritin levels, and transferrin saturation.

  • ADHD Management: Methylphenidate or atomoxetine is recommended as an initial treatment with a combined behavioral treatment approach for 4-year-old children with ADHD.

  • Azithromycin and Coronary Artery Disease: The use of azithromycin in patients with coronary artery disease is considered carefully due to a potential adverse effect on left ventricular function.

  • Intranasal Medications for Allergic Rhinitis: Seasonal allergic rhinitis is managed with intranasal glucocorticoids or cromolyn sodium.

  • Construction Worker Injury: A 30-year-old construction worker suffered an injury to his anterolateral leg. Urgent orthopedic consultation may be required due to potential need for a fasciotomy.

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Description

Test your knowledge on various medical conditions and appropriate diagnostic approaches for patients exhibiting symptoms such as numbness, elevated AST levels, and asthma. This quiz includes cases like acute coronary angiography complications and morbid obesity. Challenge yourself to determine the best next steps in diagnosis and treatment based on the provided cases.

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