Medical Diagnosis Quiz
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Questions and Answers

What is the most likely cause of symptoms in a young, healthy patient feeling doom and hyperventilating?

  • Panic disorder (correct)
  • Cardiac arrhythmia
  • Pulmonary embolism
  • Mitral valve prolapse
  • What characterizes orthostatic hypotension?

  • Drop of systolic BP by >20 mmHg and diastolic BP by >10 mmHg (correct)
  • Symptoms occur only in supine position
  • No change in blood pressure when changing positions
  • Increase in systolic BP upon standing
  • Which factor is a significant risk for developing orthostatic hypotension?

  • Sudden weight gain
  • High salt diet
  • Excessive exercise
  • Diuretic use (correct)
  • What is a characteristic symptom of vasovagal syncope triggered by stress?

    <p>Lightheadedness followed by fainting</p> Signup and view all the answers

    What mechanism is involved in carotid sinus hypersensitivity?

    <p>Excessive firing of CN IX to the solitary nucleus</p> Signup and view all the answers

    What is a typical presentation of costochondritis?

    <p>Chest pain worsens with palpation</p> Signup and view all the answers

    Which diagnostic procedure can confirm vasovagal syncope symptoms?

    <p>Tilt-table test</p> Signup and view all the answers

    What should be considered when diagnosing panic disorder over mitral valve prolapse?

    <p>Asymptomatic nature of mitral valve prolapse</p> Signup and view all the answers

    What condition is characterized by sharp lateral chest pain due to intercostal muscle spasm?

    <p>Pleurodynia</p> Signup and view all the answers

    In which condition would you expect the creatine kinase (CK) levels to be normal?

    <p>Viral pleurisy</p> Signup and view all the answers

    Which examination technique is the first step in diagnosing arterial disease?

    <p>Ankle-brachial index (ABI)</p> Signup and view all the answers

    What distinctive feature does arterial disease present in patients over 50 with risk factors?

    <p>Diminished peripheral pulses</p> Signup and view all the answers

    Which condition can cause angina-like pain in a patient who does not have cardiovascular disease?

    <p>Diffuse esophageal spasm</p> Signup and view all the answers

    What is the primary mechanism of action of statins?

    <p>Inhibit HMG-CoA reductase</p> Signup and view all the answers

    How do bile acid sequestrants primarily affect cholesterol levels?

    <p>Promote cholesterol extraction from the blood</p> Signup and view all the answers

    Which type of angina is characterized by predictable chest pain during exercise?

    <p>Stable angina</p> Signup and view all the answers

    What is the primary action of nitrates in treating stable angina?

    <p>Decrease myocardial oxygen demand</p> Signup and view all the answers

    Which drug is contraindicated with PDE-5 inhibitors like Viagra due to the risk of low blood pressure?

    <p>Isosorbide dinitrate</p> Signup and view all the answers

    What commonly appears on the ECG during unstable angina?

    <p>ST depression</p> Signup and view all the answers

    Which condition is known for causing chest pain that occurs unpredictably and may arise at rest?

    <p>Unstable angina</p> Signup and view all the answers

    What is another name for vasospastic angina?

    <p>Prinzmetal angina</p> Signup and view all the answers

    What is the primary empiric treatment for endocarditis that targets gram-positive bacteria, including MRSA?

    <p>Vancomycin</p> Signup and view all the answers

    Which of the following is NOT an indication for endocarditis prophylaxis prior to a dental procedure?

    <p>Mitral valve prolapse</p> Signup and view all the answers

    Which of the following conditions results from Streptococcus pyogenes infection and is characterized by a cross-reactivity with the mitral valve?

    <p>Rheumatic fever</p> Signup and view all the answers

    What symptom is NOT part of the JONES criteria associated with rheumatic fever?

    <p>Myocardial infarction</p> Signup and view all the answers

    What should be administered to a patient with a history of heart transplant and valvular regurgitation prior to a dental procedure?

    <p>Ampicillin</p> Signup and view all the answers

    Which of the following is characteristic of the autoimmune response in rheumatic fever?

    <p>Cross-reactivity with the mitral valve</p> Signup and view all the answers

    Which medication is typically used to treat a Group A Streptococcus infection to prevent rheumatic fever?

    <p>Penicillin</p> Signup and view all the answers

    Which of the following heart conditions does NOT require prophylaxis for endocarditis?

    <p>Bicuspid aortic valve</p> Signup and view all the answers

    Which bacterial organism is the most common cause of acute endocarditis in IV drug users?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    Which of the following conditions is most likely to lead to subacute endocarditis?

    <p>Congenital bicuspid aortic valve</p> Signup and view all the answers

    What is the significance of performing blood cultures before initiating antibiotic treatment in suspected endocarditis cases?

    <p>To identify the specific organism for targeted therapy</p> Signup and view all the answers

    Which echocardiography method is preferred for confirming a diagnosis of endocarditis?

    <p>Transesophageal echocardiography (TEE)</p> Signup and view all the answers

    Which of the following clinical findings would most likely indicate endocarditis?

    <p>New-onset murmur and fever</p> Signup and view all the answers

    Which of the following statements about Staphylococcus aureus is true in the context of endocarditis?

    <p>It is coagulase positive</p> Signup and view all the answers

    Reactive thrombocytosis in the context of endocarditis could indicate what?

    <p>An acute phase response to infection</p> Signup and view all the answers

    What symptom might suggest a septic embolus in a patient with endocarditis?

    <p>Focal neurologic signs</p> Signup and view all the answers

    What is the main treatment for Prinzmetal angina?

    <p>Dihydropyridine calcium channel blockers</p> Signup and view all the answers

    What defines a hypertensive emergency?

    <p>Blood pressure &gt;180/120 with signs of end-organ damage</p> Signup and view all the answers

    Which of the following medications should be avoided in patients with Prinzmetal angina?

    <p>Alpha-agonists</p> Signup and view all the answers

    In managing a hypertensive emergency, blood pressure should not be reduced by more than what percentage in the first hour?

    <p>20-25%</p> Signup and view all the answers

    Which type of shock is characterized by early increased systemic vascular resistance (SVR)?

    <p>Septic shock</p> Signup and view all the answers

    What condition is indicated by hypertensive urgency?

    <p>Blood pressure &gt;180/120 without signs of end-organ damage</p> Signup and view all the answers

    What is a key indicator of cardiogenic shock on pulmonary capillary wedge pressure (PCWP)?

    <p>One of the highest values for PCWP</p> Signup and view all the answers

    Which drug is commonly used for the management of urgent hypertension?

    <p>IV sodium nitroprusside</p> Signup and view all the answers

    Study Notes

    Cardiomyopathy

    • Dilated Cardiomyopathy (DCM): Characterized by diffuse 4-chamber dilation and systolic dysfunction (reduced ejection fraction, typically <55%).
    • Causes of DCM: Alcohol, thiamine deficiency (wet beriberi), viral infections (coxsackie B virus, cocaine, Chagas disease), drugs (doxorubicin), pregnancy, hemochromatosis, rheumatic heart disease, and heart failure from hypertension.
    • Hypertrophic Cardiomyopathy (HCM): Characterized by diastolic dysfunction, with a normal ejection fraction but difficulty with ventricular expansion.
    • Causes of HCM: Genetic mutations, particularly in beta-myosin heavy chain genes.
    • Hypertrophic Obstructive Cardiomyopathy (HOCM): A subtype of HCM characterized by asymmetric septal hypertrophy, sometimes obstructing the left ventricular outflow tract.
    • Restrictive Cardiomyopathy (RCM): Characterized by decreased ventricular compliance, often due to conditions like amyloidosis, hemochromatosis, or radiation-induced fibrosis.

    Atherosclerosis

    • Risk factors: Diabetes Mellitus (types I and II), smoking, and hypertension (in descending order of impact).
    • Mechanism: Atherosclerosis involves plaque buildup in arteries. High blood pressure accelerates this process by increasing damage to the inner lining of the carotid arteries. Plaques can calcify, and greater calcium signifies greater maturity of the plaque.
    • Clinical Significance: Atherosclerosis is a key risk factor for strokes, transient ischemic attacks (TIAs), and retinal artery occlusions. In older patients with risk factors and accelerated hypertension, renal artery stenosis is worth considering.

    Angina

    • Stable Angina: Predictable chest pain, typically triggered by exertion or stress and relieved by rest or nitroglycerin.
    • Causes: Atherosclerotic plaques, usually > 70% occlusion, often calcified.
    • ECG findings: ST depressions are classically observed.
    • Treatment: Nitrates (like isosorbide dinitrate) increase cGMP and relax venous smooth muscle, reducing venous return and myocardial oxygen demand. However, avoid nitrates with PDE5 inhibitors to prevent dangerous hypotension.
    • Unstable Angina: Unpredictable chest pain, often occurring at rest and not relieved by nitroglycerin or rest; more severe.
    • Treatment: Diltiazem, nitrates, and potentially cardiac catheterization are potential treatments; more severe cases may necessitate hospitalization.
    • Prinzmetal (Variant) Angina: Spasms of the coronary arteries causing chest pain, typically at rest, but can occur with exercise and stress.
    • ECG findings: ST elevations.
    • Treatment: Nitrates, dihydropyridine calcium channel blockers (e.g., nifedipine). Avoid a1 agonists and nonselective beta-blockers.

    Hypertensive Emergency and Urgency

    • Emergency: Blood pressure >180/120 mmHg accompanied by symptoms of end-organ damage (e.g., hypertensive encephalopathy, acute heart failure, or nephropathy).
    • Urgent: Blood pressure >180/120 mmHg without significant end-organ damage.
    • Treatment: Rapid reduction of blood pressure to prevent further damage, using IV medications like sodium nitroprusside, nicardipine, labetalol, or oral medications like captopril.

    Endocarditis

    • Causes: Bacterial infections, with Staphylococcus aureus being a common cause for acute endocarditis in intravenous drug users and Streptococcus viridans in patients with pre-existing valvular abnormalities or prior dental procedures.
    • Clinical presentation: New murmur accompanied by fever.
    • Diagnosis: Blood cultures and transesophageal echocardiography (TEE).
    • Treatment: Empiric antibiotic therapy, often a combination of vancomycin (aimed at gram-positive bacteria) plus gentamicin (against gram-negative bacteria) or penicillin/cefoxitin.

    Rheumatic Heart Disease

    • Causes: Immunological response to Group A streptococcal (GAS) pharyngeal infection.
    • Clinical Manifestations: Can lead to mitral valve issues, including acute mitral regurgitation and later mitral stenosis.
    • Jones criteria: Joints (polyarthritis), Carditis (valve damage), Subcutaneous nodules (small lumps under the skin), Erythema marginatum (characteristic rash), Sydenham chorea (neurological movement disorder).
    • Treatment: Penicillin administration is vital.

    Arterial Disease

    • Causes: Atherosclerosis with plaque buildup in arteries.
    • Symptoms: Diminished peripheral pulses, shiny/glabrous lower legs, small, punched-out arterial ulcers on the tops and bottoms of the feet and toes.
    • Diagnosis: Ankle-brachial index (ABI), Doppler ultrasound or arteriography.
    • Treatment: Lifestyle modifications (diet and exercise), medications (antihypertensives, statins, antiplatelet agents), and potentially surgery for severe cases.

    Venous Disease

    • Cause: Valvular incompetence or venous obstruction.
    • Symptoms: Edema, varicose veins, stasis dermatitis (brown discoloration/hyperpigmentation), venous ulcers (large, sloughy ulcers located at the medial malleolus).
    • Diagnosis: Venous duplex ultrasonography.
    • Treatment: Compression stockings and potential sclerotherapy or surgical vein ligation.

    Cardiac Stress Testing

    • Purpose: Evaluate the patient's capacity for exercise tolerance and assess the risk of cardiovascular compromise and/or perioperative myocardial infarction.
    • Methods: Exercise treadmill tests (EKG monitoring and pulse oximetry) or pharmacologic stress testing (dipyridamole; dobutamine).
    • Clinical Interpretation: EKG changes (ST depression) or ischemia, or exertion-induced symptoms (dyspnea).

    Knee Trauma and Popliteal Artery Injury

    • Clinical scenario: Trauma with absent distal pulses, where knee dislocation or penetrating trauma is suspected.
    • Diagnostic Approach: Initial physical exam for knee stability and palpation for pulses followed by arteriography.
    • Treatment: Arteriography to confirm diagnosis and intervene; surgical exploration if the diagnosis is confirmed.

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    Description

    Test your knowledge on various medical conditions and symptoms such as orthostatic hypotension, vasovagal syncope, and panic disorder. This quiz covers important diagnostic considerations and presentations for each condition. Perfect for students in healthcare fields looking to reinforce their understanding of these topics.

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