Medical Biology Lecture 3: Lysosome, Cytoskeleton, and Nucleus

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What is the main function of lysosomes?

Cellular waste disposal

How is the membrane composition of lysosomes defined?

It separates the acidic interior from the cytoplasm

What type of enzymes are found in lysosomes?

Enzymes for breaking down macromolecules

How does the membrane of lysosomes differ from the endoplasmic reticulum or the nucleus?

Lysosomes have a single lipid bilayer

Which cellular component is responsible for maintaining cell shape, structure, and intracellular transport?

Cytoskeleton

What is the central role of the nucleus in cellular function?

Genetic information storage and regulation

What is the primary function of lysosomes?

Breaking down cellular waste and recycling cellular components

What role do lysosomes play in autophagy?

Fusing with phagosomes to digest engulfed materials

What maintains the acidic pH inside lysosomes?

Active transport of protons (H+) by the lysosomal membrane

What characterizes Lysosomal Storage Disorders (LSDs)?

Accumulation of undigested substances within lysosomes

What is a clinical manifestation of Lysosomal Storage Disorders (LSDs)?

Affecting the nervous system, bones, and organs

What is the definition of the cytoskeleton?

A dynamic network of protein filaments providing structural support and playing crucial roles in cell shape, movement, and division

What are microtubules composed of?

Tubulin proteins

What function does the cytoskeleton serve in maintaining cell shape?

Preventing collapse and determining cell shape

What is the role of microtubules in intracellular transport?

Acting as tracks for motor proteins

What is a common clinical manifestation of Lysosomal Storage Disorders (LSDs)?

Varying effects on the nervous system, bones, and other organs

This lecture covers the structure, function, and diseases associated with lysosomes, cytoskeleton, and the nucleus. Understanding these cellular components is essential in the study of cell biology and medicine.

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