Cell-Cell Junctions in Medical Biology
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Questions and Answers

What is the contribution of E-cadherin loss to cancer development?

  • Increased expression of actin microfilaments
  • Enhanced cell-cell communication
  • Increased intermediate filament formation
  • Formation of metastasis in epithelial tissue cancers (correct)
  • What type of cell-cell junction is characterized by a belt-like structure?

  • Tight junction
  • Desmosome
  • Zonula adherens (correct)
  • Gap junction
  • Which type of junction permits the direct transfer of ions and small molecules?

  • Gap junction (correct)
  • Zonula occludens
  • Tight junction
  • Desmosome
  • What is the structure of anchoring junctions?

    <p>Transmembrane cadherin proteins - intracellular catenin proteins - linked to intermediate filaments</p> Signup and view all the answers

    What is the autoimmune disease characterized by blister formation due to autoantibodies against cadherin proteins?

    <p>Pemphigus</p> Signup and view all the answers

    Which type of cell-cell junction is characterized by a spot-like structure?

    <p>Macula adherens</p> Signup and view all the answers

    What type of filaments is zonula adherens associated with?

    <p>Actin microfilaments</p> Signup and view all the answers

    What is the function of gap junctions in the inner ear?

    <p>Permits the direct transfer of ions and small molecules</p> Signup and view all the answers

    What type of cell-cell junction is formed between heart muscle cells?

    <p>Anchoring junction</p> Signup and view all the answers

    What is the role of catenin proteins in cell-cell junctions?

    <p>Links transmembrane cadherin proteins to the cytoskeleton</p> Signup and view all the answers

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