Cell-Cell Junctions in Medical Biology

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What is the contribution of E-cadherin loss to cancer development?

Formation of metastasis in epithelial tissue cancers

What type of cell-cell junction is characterized by a belt-like structure?

Zonula adherens

Which type of junction permits the direct transfer of ions and small molecules?

Gap junction

What is the structure of anchoring junctions?

Transmembrane cadherin proteins - intracellular catenin proteins - linked to intermediate filaments

What is the autoimmune disease characterized by blister formation due to autoantibodies against cadherin proteins?

Pemphigus

Which type of cell-cell junction is characterized by a spot-like structure?

Macula adherens

What type of filaments is zonula adherens associated with?

Actin microfilaments

What is the function of gap junctions in the inner ear?

Permits the direct transfer of ions and small molecules

What type of cell-cell junction is formed between heart muscle cells?

Anchoring junction

What is the role of catenin proteins in cell-cell junctions?

Links transmembrane cadherin proteins to the cytoskeleton

Learn about the different types of cell-cell junctions, including transient, stable, occluding, anchoring, and communicating junctions. Understand the characteristics and functions of each type. This quiz is perfect for students of medical biology and cell biology.

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