Mediators of Acute Inflammation Quiz
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Questions and Answers

What is the main action of histamine?

  • Inhibition of chemotaxis
  • Stimulation of platelet aggregation
  • Decreased vascular permeability and vasoconstriction of venules
  • Increased vascular permeability and vasodilation of venules (correct)
  • Where is serotonin primarily sourced from?

  • Mast cell granules
  • Platelet granules (correct)
  • Plasma
  • Lysosomes
  • What are the main actions of serotonin?

  • Decreased vascular permeability and vasoconstriction of venules
  • Actions similar to histamine (correct)
  • Inhibition of chemotaxis
  • Stimulation of platelet aggregation
  • What influences vasomotor phenomena, vascular permeability, chemotaxis, and pain in the inflammatory process?

    <p>Exogenous and endogenous mediators</p> Signup and view all the answers

    What is the source of arachidonic acid derivatives such as prostaglandins and leucotrienes?

    <p>Cell-derived sources</p> Signup and view all the answers

    Which of the following is an exogenous mediator of acute inflammation?

    <p>Peptides of E. coli</p> Signup and view all the answers

    What is the main action of histamine?

    <p>Increased vascular permeability and vasodilation of venules</p> Signup and view all the answers

    Where is serotonin (5-hydroxytryptamine) sourced from?

    <p>Platelet granules</p> Signup and view all the answers

    Which of the following is an action of arachidonic acid derivatives?

    <p>Influencing vasomotor phenomena</p> Signup and view all the answers

    What are the main sources of vasoactive amines?

    <p>Mast cell and platelet granules</p> Signup and view all the answers

    Study Notes

    Histamine and Serotonin

    • Histamine plays a crucial role in vasodilation, increasing vascular permeability, and smooth muscle contraction.
    • Serotonin (5-hydroxytryptamine) is primarily sourced from the enterochromaffin cells of the intestinal mucosa and the serotonergic neurons of the central nervous system.

    Actions of Serotonin

    • Serotonin causes vasoconstriction, reduces inflammation, and modulates pain perception.

    Arachidonic Acid Derivatives

    • Arachidonic acid derivatives, such as prostaglandins and leukotrienes, influence vasomotor phenomena, vascular permeability, chemotaxis, and pain in the inflammatory process.
    • These derivatives are sourced from the cell membrane phospholipids.

    Exogenous Mediator of Acute Inflammation

    • Bradykinin is an exogenous mediator of acute inflammation.

    Vasoactive Amines

    • The main sources of vasoactive amines are mast cells, platelets, and enterochromaffin cells.

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    Description

    Test your knowledge of the mediators of acute inflammation with this quiz. Explore the role of exogenous and endogenous mediators, including vasoactive amines, arachidonic acid derivatives, and more.

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