Podcast
Questions and Answers
What is the main action of histamine?
What is the main action of histamine?
- Inhibition of chemotaxis
- Stimulation of platelet aggregation
- Decreased vascular permeability and vasoconstriction of venules
- Increased vascular permeability and vasodilation of venules (correct)
Where is serotonin primarily sourced from?
Where is serotonin primarily sourced from?
- Mast cell granules
- Platelet granules (correct)
- Plasma
- Lysosomes
What are the main actions of serotonin?
What are the main actions of serotonin?
- Decreased vascular permeability and vasoconstriction of venules
- Actions similar to histamine (correct)
- Inhibition of chemotaxis
- Stimulation of platelet aggregation
What influences vasomotor phenomena, vascular permeability, chemotaxis, and pain in the inflammatory process?
What influences vasomotor phenomena, vascular permeability, chemotaxis, and pain in the inflammatory process?
What is the source of arachidonic acid derivatives such as prostaglandins and leucotrienes?
What is the source of arachidonic acid derivatives such as prostaglandins and leucotrienes?
Which of the following is an exogenous mediator of acute inflammation?
Which of the following is an exogenous mediator of acute inflammation?
What is the main action of histamine?
What is the main action of histamine?
Where is serotonin (5-hydroxytryptamine) sourced from?
Where is serotonin (5-hydroxytryptamine) sourced from?
Which of the following is an action of arachidonic acid derivatives?
Which of the following is an action of arachidonic acid derivatives?
What are the main sources of vasoactive amines?
What are the main sources of vasoactive amines?
Flashcards
Histamine action
Histamine action
Increases vascular permeability and causes vasodilation of venules.
Source of serotonin
Source of serotonin
Primarily sourced from platelet granules in the blood.
Actions of serotonin
Actions of serotonin
Similar actions to histamine, affecting blood vessels and inflammation.
Inflammatory mediators
Inflammatory mediators
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Source of arachidonic acid derivatives
Source of arachidonic acid derivatives
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Exogenous mediator of acute inflammation
Exogenous mediator of acute inflammation
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Main action of arachidonic acid derivatives
Main action of arachidonic acid derivatives
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Sources of vasoactive amines
Sources of vasoactive amines
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Vascular permeability
Vascular permeability
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Vasodilation
Vasodilation
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Study Notes
Histamine and Serotonin
- Histamine plays a crucial role in vasodilation, increasing vascular permeability, and smooth muscle contraction.
- Serotonin (5-hydroxytryptamine) is primarily sourced from the enterochromaffin cells of the intestinal mucosa and the serotonergic neurons of the central nervous system.
Actions of Serotonin
- Serotonin causes vasoconstriction, reduces inflammation, and modulates pain perception.
Arachidonic Acid Derivatives
- Arachidonic acid derivatives, such as prostaglandins and leukotrienes, influence vasomotor phenomena, vascular permeability, chemotaxis, and pain in the inflammatory process.
- These derivatives are sourced from the cell membrane phospholipids.
Exogenous Mediator of Acute Inflammation
- Bradykinin is an exogenous mediator of acute inflammation.
Vasoactive Amines
- The main sources of vasoactive amines are mast cells, platelets, and enterochromaffin cells.
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Description
Test your knowledge of the mediators of acute inflammation with this quiz. Explore the role of exogenous and endogenous mediators, including vasoactive amines, arachidonic acid derivatives, and more.
