9 Questions
What is the primary mechanism of action of Tigecycline?
Inhibition of protein synthesis
Which bacteria are Tigecycline effective against?
Both Gram-positive and Gram-negative bacteria
What is the main advantage of Tigecycline over tetracyclines?
Overcomes bacterial resistance mechanisms
How does Tigecycline compare to Vancomycin in terms of activity?
Tigecycline is more effective against Gram-positive bacteria than Vancomycin
Which of the following is a contraindication for using Tigecycline?
Pregnancy
What is the primary target of Fusidic acid in bacterial cells?
Protein synthesis
Which factor contributes to Fusidic acid's inhibition of protein synthesis?
Forming a complex with ribosome and EF-G
What distinguishes Tigecycline from tetracyclines in terms of resistance mechanisms?
Resistance due to altered ribosomal binding site and efflux pumps acquisition only
What adverse effect might be associated with Tigecycline use during tooth development in children?
Tooth discoloration
Learn about the mechanism of action of macrolide antibiotics, how they bind at the P-site of the ribosomal subunit to inhibit protein synthesis, their spectrum of activity against certain types of bacteria, and their uses and side effects.
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