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Questions and Answers
What is the mechanism of action of macrolides?
What is the mechanism of action of macrolides?
- Inhibition of DNA replication
- Blocking of cell membrane transport
- Reversible binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis (correct)
- Inhibition of cell wall synthesis
Which of the following is a characteristic of macrolides' gastrointestinal absorption?
Which of the following is a characteristic of macrolides' gastrointestinal absorption?
- Rapid and complete absorption
- Variable absorption (correct)
- Poor absorption in acidic environment
- Consistent and complete absorption
What is the mechanism of resistance to macrolides?
What is the mechanism of resistance to macrolides?
- Alteration in cell membrane permeability (correct)
- Enhanced efflux pumps
- Increased production of beta-lactamase
- Mutation in the 30S ribosomal subunit
What is a unique characteristic of azithromycin compared to other macrolides?
What is a unique characteristic of azithromycin compared to other macrolides?
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What is a common adverse effect of macrolides?
What is a common adverse effect of macrolides?
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What is a unique feature of clarithromycin?
What is a unique feature of clarithromycin?
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