6 Questions
What is the mechanism of action of macrolides?
Reversible binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis
Which of the following is a characteristic of macrolides' gastrointestinal absorption?
Variable absorption
What is the mechanism of resistance to macrolides?
Alteration in cell membrane permeability
What is a unique characteristic of azithromycin compared to other macrolides?
Better activity against Haemophilus
What is a common adverse effect of macrolides?
Gastrointestinal disturbances
What is a unique feature of clarithromycin?
It has a hydroxy metabolite
Learn about the mechanism of action of macrolides, a class of antibiotics, and how they inhibit protein synthesis. Understand how resistance to macrolides develops and their properties, including gastrointestinal absorption and ability to cross the blood-brain barrier.
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