Podcast
Questions and Answers
What is the role of integrin in cellular function?
What is the role of integrin in cellular function?
- Promotes collagen breakdown
- Enhances microfilament contraction
- Aids in cell adhesion (correct)
- Increases muscle tissue strength
Which component provides intercellular tensegrity through microfilaments of non-contractile actin/myosin?
Which component provides intercellular tensegrity through microfilaments of non-contractile actin/myosin?
- Integrin
- Collagen (correct)
- Fibronectin
- Glycosaminoglycans
How does collagen content vary across musculoskeletal tissues?
How does collagen content vary across musculoskeletal tissues?
- Tendons have the least collagen percentage
- Collagen content is highest in bone tissue
- Collagen is most abundant in cartilage
- Collagen constitutes 1-2% of muscle tissue (correct)
What effect does aging have on collagen structure?
What effect does aging have on collagen structure?
Which molecule is responsible for the stability of the collagen structure?
Which molecule is responsible for the stability of the collagen structure?
During which phase of tissue healing does collagen deposition result in increased scar tensile strength to about 15% of normal tissue?
During which phase of tissue healing does collagen deposition result in increased scar tensile strength to about 15% of normal tissue?
What is the main matrix element of dense connective tissue?
What is the main matrix element of dense connective tissue?
What stimulates capillary budding from healthy arterioles to form mature blood vessels during tissue healing?
What stimulates capillary budding from healthy arterioles to form mature blood vessels during tissue healing?
Which type of collagen is the main component of reticular fibers?
Which type of collagen is the main component of reticular fibers?
In which phase of tissue healing does fibroplasia occur, leading to scar formation?
In which phase of tissue healing does fibroplasia occur, leading to scar formation?
What characterizes the tensile strength of a wound during the fibroblastic repair phase?
What characterizes the tensile strength of a wound during the fibroblastic repair phase?
What is the most common type of collagen in the human body?
What is the most common type of collagen in the human body?
Which type of collagen forms the basal lamina in the body?
Which type of collagen forms the basal lamina in the body?
In dense connective tissue, what is crowded between the collagen fibers?
In dense connective tissue, what is crowded between the collagen fibers?
What is the term used to describe the process of collagen fibers combining to form distinct waveforms or 'Crimp' to promote tissue stiffness?
What is the term used to describe the process of collagen fibers combining to form distinct waveforms or 'Crimp' to promote tissue stiffness?
Excessive un-crimping of collagen fascicles will result in:
Excessive un-crimping of collagen fascicles will result in:
What are the three external forces that can cause deformation in collagen?
What are the three external forces that can cause deformation in collagen?
Collagen compliance in tendons and ligaments is primarily a function of:
Collagen compliance in tendons and ligaments is primarily a function of:
During the maturation-remodeling phase of tissue healing, what is the process that involves increased stress and strain resulting in collagen realignment and strength?
During the maturation-remodeling phase of tissue healing, what is the process that involves increased stress and strain resulting in collagen realignment and strength?
What is the typical timeframe for collagen to reach about 20% of its normal strength during the maturation-remodeling phase?
What is the typical timeframe for collagen to reach about 20% of its normal strength during the maturation-remodeling phase?
Which type of scar is typically present after 3-4 weeks in the maturation-remodeling phase?
Which type of scar is typically present after 3-4 weeks in the maturation-remodeling phase?
Which theory describes increased stress and strain leading to collagen realignment and strength during tissue healing?
Which theory describes increased stress and strain leading to collagen realignment and strength during tissue healing?
What is the definition of strain in the context of collagen?
What is the definition of strain in the context of collagen?
What does stiffness refer to in terms of collagen?
What does stiffness refer to in terms of collagen?
What term is used to describe the combination of viscosity and elasticity in collagen?
What term is used to describe the combination of viscosity and elasticity in collagen?
How does collagen respond to different rates of loading?
How does collagen respond to different rates of loading?
What does a tissue with increased viscosity demonstrate in terms of stress-strain slopes?
What does a tissue with increased viscosity demonstrate in terms of stress-strain slopes?
What happens to collagen under a specific load applied over time?
What happens to collagen under a specific load applied over time?
When collagen deformation occurs over time, what happens to the internal stress within the collagen?
When collagen deformation occurs over time, what happens to the internal stress within the collagen?
What is the term used to describe the phenomenon where a viscoelastic material shows different loading and unloading curves?
What is the term used to describe the phenomenon where a viscoelastic material shows different loading and unloading curves?
What does hysteresis represent in the context of a viscoelastic material?
What does hysteresis represent in the context of a viscoelastic material?
How does hysteresis change with cyclical loading on a tendon?
How does hysteresis change with cyclical loading on a tendon?
What causes pain when the viscoelastic properties of collagen have been exceeded?
What causes pain when the viscoelastic properties of collagen have been exceeded?
In what way does collagen respond to a constant load over time?
In what way does collagen respond to a constant load over time?
What is the term used to describe the reduction of internal forces in a tendon due to elongation under low load passive stretch?
What is the term used to describe the reduction of internal forces in a tendon due to elongation under low load passive stretch?
"The difference between the loading and unloading curve of a viscoelastic material represents:"
"The difference between the loading and unloading curve of a viscoelastic material represents:"
