Mastering the World of Antibiotics
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Mastering the World of Antibiotics

Test your knowledge on antibiotics and chemotherapy with this quiz! Explore the different classifications of antibiotics based on their origin, chemical structure, action on microbes, effect on microbes, and mode of action. Sharpen your understanding of these essential topics in microbiology.

Created by
@DelectableReasoning5796

Questions and Answers

According to their origin, antibiotics can be classified into categories based on their

Sources

Who discovered penicillin?

Sir Alexander Fleming

What was the first member of the β-lactam class of antibiotics to be discovered?

Penicillin

What is the definition of an antibiotic?

<p>A substance produced by one microorganism that inhibits the growth of other microorganisms</p> Signup and view all the answers

What modification of the definition of an antibiotic occurred with the advent of synthetic methods?

<p>The definition narrowed to include only substances produced by synthetic methods</p> Signup and view all the answers

Which of the following antibiotics inhibits protein synthesis by binding to the 30S ribosomal subunit?

<p>Aminoglycosides</p> Signup and view all the answers

Which subunit of the bacterial ribosome is affected by tetracyclines?

<p>30S</p> Signup and view all the answers

Which antibiotics affect the 50S ribosomal subunit?

<p>Macrolides</p> Signup and view all the answers

Which of the following antibiotics inhibits protein synthesis by binding to the 30S ribosomal subunit and crossing the outer bacterial membrane through porin channels?

<p>Aminoglycosides</p> Signup and view all the answers

Which phase of translation in the bacterial ribosome involves the binding of the ribosome to the mRNA and the start codon?

<p>Initiation</p> Signup and view all the answers

Study Notes

Antibiotics Classification

  • Antibiotics can be classified into categories based on their origin.

Discovery of Penicillin

  • Penicillin was discovered by Alexander Fleming.

β-Lactam Class of Antibiotics

  • Penicillin was the first member of the β-lactam class of antibiotics to be discovered.

Definition of Antibiotics

  • Antibiotics are substances that inhibit the growth of or kill microorganisms.

Modification of Antibiotic Definition

  • With the advent of synthetic methods, the definition of antibiotics was modified to include synthetic substances that inhibit the growth of or kill microorganisms.

Antibiotics Inhibiting Protein Synthesis

  • Tetracyclines inhibit protein synthesis by binding to the 30S ribosomal subunit.
  • Streptomycin inhibits protein synthesis by binding to the 30S ribosomal subunit and crossing the outer bacterial membrane through porin channels.

Ribosomal Subunit Affected by Antibiotics

  • Tetracyclines affect the 30S ribosomal subunit.
  • Macrolides, Chloramphenicol, and Lincosamides affect the 50S ribosomal subunit.

Translation Phase in Bacterial Ribosome

  • The initiation phase of translation involves the binding of the ribosome to the mRNA and the start codon.

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