Podcast
Questions and Answers
Which antibiotic is classified under natural penicillins?
Which antibiotic is classified under natural penicillins?
Which generation of cephalosporins does Cefepime belong to?
Which generation of cephalosporins does Cefepime belong to?
Which antibiotic inhibits bacterial protein synthesis at the 30S ribosomal subunit?
Which antibiotic inhibits bacterial protein synthesis at the 30S ribosomal subunit?
Which antibiotic is a glycopeptide?
Which antibiotic is a glycopeptide?
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Doripenem is classified under which category?
Doripenem is classified under which category?
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Which of the following is not a beta lactam antibiotic?
Which of the following is not a beta lactam antibiotic?
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Ciprofloxacin belongs to which class of antibiotics?
Ciprofloxacin belongs to which class of antibiotics?
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Which antibiotic is an inhibitor of the 50S ribosomal subunit?
Which antibiotic is an inhibitor of the 50S ribosomal subunit?
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Study Notes
Inhibition of Cell Wall Synthesis
- Beta-lactam antibiotics inhibit cell wall synthesis
- Penicillins are classified into natural penicillins, antistaphylococcal penicillins, aminopenicillins, broad spectrum penicillins, and anti-pseudomonal penicillins
- Cephalosporins are classified into five generations (1st to 5th)
Inhibition of Protein Synthesis
- 30S inhibitors: tetracyclines, glycylcyclines, and aminoglycosides act on the 30S ribosomal subunit
- 50S inhibitors: macrolides, ketolides, macrocyclic, chloramphenicol, oxazolidinones, lincosamides, and streptogramins act on the 50S ribosomal subunit
Inhibition of Nucleic Acid Synthesis
- Topoisomerases inhibit DNA synthesis
- Quinolones, including second, third, and fourth generations, and fluoroquinolones, also inhibit nucleic acid synthesis
Other Mechanisms
- Antifolates, including DHFR inhibitors and CO, inhibit folate synthesis
- Monobactams, carbapenems, and glycopeptide antibiotics have unique mechanisms of action
- Other antibiotics with distinct mechanisms include methicillin, nafcillin, and oxacillin
Antibiotics
- List of penicillin-based antibiotics: penicillin G, procaine penicillin G, benzathine penicillin G, methicillin, nafcillin, and others
- List of cephalosporin-based antibiotics: cefadroxil, cephalexin, cefradine, cefazolin, and many others
- List of carbapenem-based antibiotics: imipenem, meropenem, doripenem
- List of monobactam-based antibiotics: aztreonam
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Description
This quiz covers the classification of antibiotics based on their mechanisms of action and chemical structure, including beta lactams, cephalosporins, and more.
