Mastering the Intricacies of Cerebrospinal Fluid and the Blood-Brain Barrier
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Questions and Answers

Which of the following is a histological characteristic of the blood-brain barrier?

  • Polarized endothelium (correct)
  • Many fenestrations
  • Loose junctions
  • Frequent pinocytosis

    • Which type of molecules can easily pass through the capillary endothelium of the blood-brain barrier?

  • Protein-bound molecules
  • Large, charged molecules
  • Small, uncharged, lipid soluble molecules (correct)
  • Water molecules

    • What is the main function of the blood-brain barrier?

  • To regulate the flow of cerebrospinal fluid
  • To allow the passage of harmful substances into the nervous tissue
  • To facilitate the exchange of oxygen and carbon dioxide
  • To protect the brain from potentially harmful substances (correct)

    • Which transport system is responsible for the uptake of glucose at the blood-brain barrier?

    <p>MCT</p> Signup and view all the answers

    What is the function of OATs at the blood-brain barrier?

    <p>Transport of organic anions</p> Signup and view all the answers

    What are the three meninges?

    <p>Dura mater, arachnoid mater, pia mater</p> Signup and view all the answers

    Where is cerebrospinal fluid formed?

    <p>In the ventricles of the brain</p> Signup and view all the answers

    What is hydrocephalus?

    <p>Blockage of cerebrospinal fluid flow</p> Signup and view all the answers

    What are the components of the blood-brain barrier?

    <p>Endothelium, pericytes, astrocytes</p> Signup and view all the answers

    Why is a functioning blood-brain barrier important?

    <p>To protect the brain from potentially harmful substances</p> Signup and view all the answers

    Which one of these is NOT one of the meninges?

    <p>Cerebrospinal mater</p> Signup and view all the answers

    What is the function of cerebrospinal fluid (CSF)?

    <p>All of the above</p> Signup and view all the answers

    Where is cerebrospinal fluid (CSF) formed?

    <p>All of the above</p> Signup and view all the answers

    What is the role of the choroid plexus in CSF production?

    <p>To produce CSF at a constant rate</p> Signup and view all the answers

    Which ventricle is located between the cerebellum and the dorsal surface of the hindbrain?

    <p>Fourth ventricle</p> Signup and view all the answers

    What is the function of the blood-brain barrier?

    <p>To form a selective, tight-junction barrier</p> Signup and view all the answers

    Which cells form a selective, tight-junction barrier in the blood-brain barrier?

    <p>Astrocytes</p> Signup and view all the answers

    What is the role of the leaky capillaries in the blood-brain barrier?

    <p>To secrete substances into the CSF</p> Signup and view all the answers

    What is the importance of a functioning blood-brain barrier?

    <p>To protect the brain from harmful substances</p> Signup and view all the answers

    What is hydrocephalus?

    <p>An excess buildup of CSF in the brain</p> Signup and view all the answers

    Which of the following is true about cerebrospinal fluid (CSF)?

    <p>Turbidity of CSF indicates increased cellularity.</p> Signup and view all the answers

    How is CSF absorbed into the venous system?

    <p>By arachnoid villi in the dural sinuses.</p> Signup and view all the answers

    What is the function of the blood-brain barrier?

    <p>To prevent passage of blood solutes through intercellular clefts.</p> Signup and view all the answers

    Where is CSF initially formed?

    <p>In the choroid plexuses.</p> Signup and view all the answers

    What causes non-communicating hydrocephalus?

    <p>Obstruction to CSF flow.</p> Signup and view all the answers

    How does CSF flow from the lateral ventricles to the subarachnoid space?

    <p>Through the foramina of Luschka.</p> Signup and view all the answers

    What does increased cellularity of CSF suggest?

    <p>Presence of blood.</p> Signup and view all the answers

    Where can CSF be sampled in most veterinary species?

    <p>In the lumbar spinal column.</p> Signup and view all the answers

    What is the function of the arachnoid villi?

    <p>To absorb CSF into the venous system.</p> Signup and view all the answers

    What is the function of astrocytic endfeet in the blood-brain barrier?

    <p>To prevent passage of blood solutes through intercellular clefts.</p> Signup and view all the answers

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