Mastering the Intricacies of Cerebrospinal Fluid and the Blood-Brain Barrier
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Questions and Answers

Which one of these is NOT one of the three meninges?

  • Cerebrospinal mater (correct)
  • Dura mater
  • Pia mater
  • Arachnoid mater

What is the function of cerebrospinal fluid (CSF)?

  • To cushion the brain
  • To maintain a consistent extracellular microenvironment for the neurons and glia cells
  • To distribute peptide hormones and growth factors secreted into the CSF
  • All of the above (correct)

Where is cerebrospinal fluid (CSF) formed?

  • In the subarachnoid space
  • In the ventricles
  • In the meninges
  • In the choroid plexus (correct)

What is the role of the blood-brain barrier?

<p>To prevent harmful substances from entering the brain (C)</p> Signup and view all the answers

Which of the following is NOT a histological characteristic of the blood-brain barrier?

<p>Fenestrations in the endothelium (A)</p> Signup and view all the answers

Which type of molecules can easily pass across the capillary endothelium of the blood-brain barrier?

<p>Small, uncharged, lipid soluble molecules (D)</p> Signup and view all the answers

Which transport system is NOT found at the blood-brain barrier?

<p>GLUT (glucose transporters) (B)</p> Signup and view all the answers

What is the main function of the blood-brain barrier?

<p>To protect the nervous tissue from potentially harmful substances (B)</p> Signup and view all the answers

Which of the following is NOT a relevant process in the production of cerebrospinal fluid (CSF)?

<p>Passive diffusion of CSF into the venous system (C)</p> Signup and view all the answers

Where does CSF flow down from its site of formation at the choroid plexuses?

<p>Into the subarachnoid space through foramina of Luschka (A)</p> Signup and view all the answers

Where is CSF sampled in humans?

<p>In the lumbar spinal column (D)</p> Signup and view all the answers

What is the primary cause of non-communicating hydrocephalus?

<p>Obstruction to CSF flow (A)</p> Signup and view all the answers

Which of the following is NOT a function of cerebrospinal fluid (CSF)?

<p>Active transport of sodium ions (Na+) and chloride (Cl-) (B)</p> Signup and view all the answers

What is the primary cause of communicating hydrocephalus?

<p>Impairment of absorption (C)</p> Signup and view all the answers

Where does CSF absorption into the venous system primarily occur?

<p>Dural sinuses (B)</p> Signup and view all the answers

What is the rate of CSF production in humans?

<p>20 mL/hr (B)</p> Signup and view all the answers

What does turbidity in CSF indicate?

<p>Increased cellularity (D)</p> Signup and view all the answers

What is the function of arachnoid villi in the absorption of CSF?

<p>Absorption of CSF into the dural sinuses (C)</p> Signup and view all the answers

What is the main function of the blood-brain barrier?

<p>Selective exchange of blood solutes (A)</p> Signup and view all the answers

What is the primary cause of non-communicating hydrocephalus?

<p>Obstruction to CSF flow (A)</p> Signup and view all the answers

Where is CSF sampled in most veterinary species?

<p>Between the skull and the first cervical vertebra (atlas) (D)</p> Signup and view all the answers

What is the primary cause of non-communicating hydrocephalus?

<p>Obstruction to CSF flow (B)</p> Signup and view all the answers

Which one of these is NOT a function of cerebrospinal fluid (CSF)?

<p>Transporting oxygen to the brain (A)</p> Signup and view all the answers

Where is the choroid plexus located?

<p>In the ventricles of the brain (B)</p> Signup and view all the answers

Which one of these is NOT a component of the meninges?

<p>Choroid plexus (D)</p> Signup and view all the answers

What is the role of the arachnoid mater?

<p>To trap cerebrospinal fluid (CSF) between it and the pia mater (C)</p> Signup and view all the answers

Where does cerebrospinal fluid (CSF) flow down from its site of formation at the choroid plexus?

<p>To the ventricles of the brain (C)</p> Signup and view all the answers

What is the main function of the blood-brain barrier?

<p>To form a selective, tight-junction barrier (D)</p> Signup and view all the answers

Which one of these is NOT a histological characteristic of the blood-brain barrier?

<p>Leaky capillaries (A)</p> Signup and view all the answers

What is the function of the pia mater?

<p>To trap cerebrospinal fluid (CSF) between it and the arachnoid mater (C)</p> Signup and view all the answers

What is the function of the dura mater?

<p>To cushion the brain (C)</p> Signup and view all the answers

What is the function of the cerebrospinal fluid (CSF)?

<p>To remove potentially harmful cellular metabolites (B)</p> Signup and view all the answers

Which of the following is NOT a functional characteristic of the blood-brain barrier?

<p>Molecules that are bound to plasma proteins can easily pass through the BBB (A)</p> Signup and view all the answers

Which transport system is NOT mentioned as a representative at the blood-brain barrier?

<p>MRPs (Multidrug Resistance Associated Protein) (B)</p> Signup and view all the answers

Which of the following is NOT a component of the blood brain barrier?

<p>Fenestrations (A)</p> Signup and view all the answers

Which of the following is NOT a learning objective mentioned in the text?

<p>Explain the flow of CSF through the CNS (A)</p> Signup and view all the answers

Which of the following is NOT a histological characteristic of the blood-brain barrier?

<p>Pinocytosis (C)</p> Signup and view all the answers

Which of the following is NOT a function of the cerebrospinal fluid (CSF)?

<p>Regulating blood flow to the brain (C)</p> Signup and view all the answers

Which of the following is NOT a site where cerebrospinal fluid (CSF) is formed?

<p>Subarachnoid space (D)</p> Signup and view all the answers

Which of the following is NOT a relevant process in the production of cerebrospinal fluid (CSF)?

<p>Reabsorption of CSF into the venous system (D)</p> Signup and view all the answers

Which of the following is NOT a meninge mentioned in the text?

<p>Cerebrospinal mater (C)</p> Signup and view all the answers

What is the main importance of a functioning blood-brain barrier?

<p>Preventing the entry of harmful substances into the nervous tissue (A)</p> Signup and view all the answers

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