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Questions and Answers
Which of the following is the final product of gene expression?
What is the main function of translation?
What is the role of the genetic code?
Which molecule is responsible for transporting amino acids during translation?
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What is the role of ribosomes in translation?
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What is the function of the wobble base in tRNA molecules?
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What is the role of aminoacyl-tRNA synthetases in translation?
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True or false: The large and small ribosome subunits are normally separated in the cytoplasm until they are used for translation.
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Which of the following is true about the initiation of translation?
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Which of the following is required for the initiation of translation?
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What is the role of release factor in translation?
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Which of the following is true about the initiation step of translation in eukaryotes?
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Which of the following is true about the elongation step of translation?
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Which of the following is true about the termination step of translation?
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Why are inhibitors of prokaryotic protein synthesis useful as antibiotics?
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Which of the following is true about the genetic code?
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What is the process by which the genetic code is translated into a polypeptide chain?
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Which of the following is involved in the process of translation?
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What is the final product of gene expression?
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What is the role of aminoacyl-tRNA synthetases in translation?
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What is the function of the wobble base in tRNA molecules?
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What is the role of ribosomes in translation?
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Which of the following is true about the genetic code?
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What is the role of tRNA in translation?
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What is the function of ribosomes in translation?
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What is the role of the wobble base in tRNA molecules?
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What is the role of aminoacyl-tRNA synthetases in translation?
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What is the function of the small ribosome subunit in translation?
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What is the function of the large ribosome subunit in translation?
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True or false: The large and small ribosome subunits are normally separated in the cytoplasm until they are used for translation.
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What is the first modification to occur in eukaryotes during mRNA processing?
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What is the role of Met-tRNA in translation?
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What is the process of preventing the translation of mRNA with no 5´-cap?
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What is the role of release factor in translation?
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What is the function of the wobble base in tRNA molecules?
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What is the role of molecular chaperones in protein folding?
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What is spliced together during mRNA processing?
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Which of the following is true about the elongation step of translation?
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Which of the following is true about the termination step of translation?
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Which of the following is true about the initiation step of translation in prokaryotes?
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What is the role of elongation factors in translation?
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What is the function of the wobble base in tRNA molecules?
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Which of the following is true about polyribosome complexes?
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Why are inhibitors of prokaryotic protein synthesis useful as antibiotics?
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Which of the following is true about the role of release factors in translation?
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Study Notes
Gene Expression and Translation
- The final product of gene expression is a protein.
- The main function of translation is to synthesize a polypeptide chain from a sequence of nucleotides in mRNA.
The Genetic Code
- The genetic code is a set of rules that translates a sequence of nucleotides into a sequence of amino acids.
- The genetic code is degenerate, meaning that more than one codon can code for the same amino acid.
Translation Machinery
- Ribosomes are responsible for translating mRNA into a polypeptide chain.
- The small ribosome subunit binds to mRNA, while the large ribosome subunit binds to tRNA.
- Ribosomes play a central role in the initiation, elongation, and termination steps of translation.
- Aminoacyl-tRNA synthetases are enzymes that attach amino acids to tRNA molecules.
- The wobble base in tRNA molecules allows for flexibility in the recognition of codons during translation.
Initiation of Translation
- The initiation of translation requires the binding of mRNA to the small ribosome subunit.
- In prokaryotes, the initiation of translation occurs when the 30S ribosomal subunit binds to the Shine-Dalgarno sequence on mRNA.
- In eukaryotes, the initiation of translation occurs when the 40S ribosomal subunit binds to the 5´-cap of mRNA.
Elongation and Termination
- During elongation, amino acids are added to the growing polypeptide chain through the formation of peptide bonds.
- The elongation step of translation requires the activity of elongation factors.
- The termination of translation occurs when a stop codon is reached, and the polypeptide chain is released from the ribosome.
- Release factors are proteins that recognize stop codons and terminate translation.
mRNA Processing
- In eukaryotes, mRNA is modified through splicing, capping, and polyadenylation before it is translated.
- The first modification to occur in eukaryotes during mRNA processing is the addition of a 5´-cap.
- The 5´-cap is required for the translation of mRNA.
Inhibitors of Protein Synthesis
- Inhibitors of prokaryotic protein synthesis are useful as antibiotics because they can selectively target bacterial ribosomes.
- These inhibitors can prevent the translation of mRNA, thereby inhibiting bacterial growth.
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Description
Test your knowledge on RNA-binding sites in the ribosome and the process of translation with this quiz. Explore the functions of the E, P, and A sites, the mRNA binding site, and the role of tRNA molecules in the process.