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Questions and Answers
Which drug is contraindicated in patients with prolonged QT interval and taking quinolone antibiotics that also prolong QT interval?
Which drug is contraindicated in patients with prolonged QT interval and taking quinolone antibiotics that also prolong QT interval?
- Procainamide (correct)
- Disopyramide
- Mexiletine
- Lidocaine
Which drug requires dose adjustment in renal impairment due to its renal clearance?
Which drug requires dose adjustment in renal impairment due to its renal clearance?
- Procainamide
- Mexiletine
- Disopyramide (correct)
- Lidocaine
Which drug is used for acute management of ventricular arrhythmias during myocardial infarction or digoxin toxicity?
Which drug is used for acute management of ventricular arrhythmias during myocardial infarction or digoxin toxicity?
- Procainamide
- Disopyramide
- Mexiletine
- Lidocaine (correct)
Which drug is metabolized in the liver by CYP2D6 into inactive metabolites?
Which drug is metabolized in the liver by CYP2D6 into inactive metabolites?
Which medications are indicated in heart failure based on the neurohormonal model of HF?
Which medications are indicated in heart failure based on the neurohormonal model of HF?
Which types of heart failure patients should not receive beta blockers (BB)?
Which types of heart failure patients should not receive beta blockers (BB)?
Describe the mortality benefits of ACE inhibitors/ARBs in heart failure treatment.
Describe the mortality benefits of ACE inhibitors/ARBs in heart failure treatment.
Which drug is contraindicated in patients with recent decompensation or NYHA class IV heart failure and chronic atrial fibrillation?
Which drug is contraindicated in patients with recent decompensation or NYHA class IV heart failure and chronic atrial fibrillation?
Which drug is indicated for rapid conversion to normal sinus rhythm in paroxysmal supraventricular tachycardia?
Which drug is indicated for rapid conversion to normal sinus rhythm in paroxysmal supraventricular tachycardia?
Which drug has a narrow therapeutic index and requires caution when used with 3A4 inhibitors/inducers?
Which drug has a narrow therapeutic index and requires caution when used with 3A4 inhibitors/inducers?
Which drug is the most frequent cause of drug-induced lupus?
Which drug is the most frequent cause of drug-induced lupus?
Which antiarrhythmic agent has a half-life of 40-60 days when taken orally?
Which antiarrhythmic agent has a half-life of 40-60 days when taken orally?
Which antiarrhythmic agent has a high incidence of QT prolongation and can cause pulmonary fibrosis at doses greater than 300mg/day?
Which antiarrhythmic agent has a high incidence of QT prolongation and can cause pulmonary fibrosis at doses greater than 300mg/day?
Which antiarrhythmic agent must be initiated in a setting with continuous EKG monitoring and ability to assess CrCl for 3 days?
Which antiarrhythmic agent must be initiated in a setting with continuous EKG monitoring and ability to assess CrCl for 3 days?
Which antiarrhythmic agent is indicated for recent onset Afib/flutter for rapid conversion to NSR and must be discontinued as soon as arrhythmia is terminated or prolonged QT interval occurs?
Which antiarrhythmic agent is indicated for recent onset Afib/flutter for rapid conversion to NSR and must be discontinued as soon as arrhythmia is terminated or prolonged QT interval occurs?
Which medication in the Vaughan Williams Classification has the ability to control ventricular rate in patients with atrial fibrillation caused by enhanced sympathetic activity?
Which medication in the Vaughan Williams Classification has the ability to control ventricular rate in patients with atrial fibrillation caused by enhanced sympathetic activity?
Which medication in the Vaughan Williams Classification has the ability to widen the QRS complex?
Which medication in the Vaughan Williams Classification has the ability to widen the QRS complex?
Which medication in the Vaughan Williams Classification delays phase 3 repolarization, resulting in marked prolongation of action potential duration (APD) and refractory period?
Which medication in the Vaughan Williams Classification delays phase 3 repolarization, resulting in marked prolongation of action potential duration (APD) and refractory period?
Which medication in the Vaughan Williams Classification blocks L-type calcium channels in cardiac tissue, slowing AV and SA node conduction velocity and decreasing automaticity?
Which medication in the Vaughan Williams Classification blocks L-type calcium channels in cardiac tissue, slowing AV and SA node conduction velocity and decreasing automaticity?
Which medication is contraindicated in patients with a history of angioedema?
Which medication is contraindicated in patients with a history of angioedema?
What is the mechanism of action of SGLT2 inhibitors in heart failure?
What is the mechanism of action of SGLT2 inhibitors in heart failure?
Which medication combination is indicated for African Americans with NYHA class III-IV heart failure who are still symptomatic despite optimal treatment with ACE inhibitors/ARBs/ARNi and beta blockers?
Which medication combination is indicated for African Americans with NYHA class III-IV heart failure who are still symptomatic despite optimal treatment with ACE inhibitors/ARBs/ARNi and beta blockers?
What is the indication for ivabradine in heart failure patients?
What is the indication for ivabradine in heart failure patients?
Which medication is contraindicated in patients with a blood pressure lower than 90/50 and has an effect on mortality?
Which medication is contraindicated in patients with a blood pressure lower than 90/50 and has an effect on mortality?
What is the mechanism of action of digoxin and its inotropic effects?
What is the mechanism of action of digoxin and its inotropic effects?
What are the adverse drug reactions (ADRs) of digoxin and how are ADRs enhanced?
What are the adverse drug reactions (ADRs) of digoxin and how are ADRs enhanced?
Which medications are indicated for heart failure with reduced ejection fraction (HFrEF)?
Which medications are indicated for heart failure with reduced ejection fraction (HFrEF)?
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