14 Questions
What is a necessary step for a drug to reach the systemic circulation, unless it is administered through which route?
Intravenously
What is the term for the process by which a drug is metabolized by the liver before it reaches the systemic circulation?
First Pass Hepatic Metabolism
Which of the following factors does not affect drug absorption?
Weather conditions
Which of the following is not a patient-related factor that affects drug absorption?
Dietary habits
What is the primary site where a drug is absorbed when administered orally?
Small intestine
What percentage of all drugs are administered by the oral route?
90%
What is the main advantage of Buccal/Sublingual delivery over Oral delivery?
By-pass First pass metabolism
Which route of administration directly delivers the drug into the bloodstream?
Intravenous route
What is the major disadvantage of Rectal delivery?
Absorption depends on disease state
Why are enteral and parenteral routes classified separately?
Because of the mode of administration
What is the main limitation of Oral delivery in unconscious patients?
Unconscious patients cannot take dose
What is the advantage of Oral delivery in terms of patient compliance?
Higher compliance
What is the primary disadvantage of Buccal/Sublingual delivery?
Discomfort during dissolution
Why is Intravenous delivery not affected by First pass metabolism?
Because it is administered directly into the bloodstream
Test your knowledge of pharmacology with this quiz covering drug absorption and distribution, including first pass hepatic metabolism and factors affecting drug absorption. Learn about the processes involved in getting a drug to the systemic circulation and how different routes of administration affect this process.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
