Pharmacology: Drug Absorption and Distribution
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Questions and Answers

What is a necessary step for a drug to reach the systemic circulation, unless it is administered through which route?

  • Intravenously (correct)
  • Orally
  • Sublingually
  • Topically

    • What is the term for the process by which a drug is metabolized by the liver before it reaches the systemic circulation?

  • First Pass Absorption
  • Systemic Metabolism
  • First Pass Hepatic Metabolism (correct)
  • Drug Distribution

    • Which of the following factors does not affect drug absorption?

  • Weather conditions (correct)
  • Patient's age
  • Drug's chemical structure
  • Route of administration

    • Which of the following is not a patient-related factor that affects drug absorption?

    <p>Dietary habits</p> Signup and view all the answers

    What is the primary site where a drug is absorbed when administered orally?

    <p>Small intestine</p> Signup and view all the answers

    What percentage of all drugs are administered by the oral route?

    <p>90%</p> Signup and view all the answers

    What is the main advantage of Buccal/Sublingual delivery over Oral delivery?

    <p>By-pass First pass metabolism</p> Signup and view all the answers

    Which route of administration directly delivers the drug into the bloodstream?

    <p>Intravenous route</p> Signup and view all the answers

    What is the major disadvantage of Rectal delivery?

    <p>Absorption depends on disease state</p> Signup and view all the answers

    Why are enteral and parenteral routes classified separately?

    <p>Because of the mode of administration</p> Signup and view all the answers

    What is the main limitation of Oral delivery in unconscious patients?

    <p>Unconscious patients cannot take dose</p> Signup and view all the answers

    What is the advantage of Oral delivery in terms of patient compliance?

    <p>Higher compliance</p> Signup and view all the answers

    What is the primary disadvantage of Buccal/Sublingual delivery?

    <p>Discomfort during dissolution</p> Signup and view all the answers

    Why is Intravenous delivery not affected by First pass metabolism?

    <p>Because it is administered directly into the bloodstream</p> Signup and view all the answers

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